Clinical Trials for Rectal Cancer

Find clinical trials for rectal cancer. Discover research opportunities and treatment options in your area.

232 Active Trials Found

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Neoadjuvant Radiotherapy for Rectal Adenocarcinoma With Capecitabine Versus TAS-102 (Neo-REACT): A Multi-center, Randomized, Phase III Trial

NCT ID: NCT06850090

This clinical trial is studying a new treatment approach for patients with locally advanced rectal cancer, specifically comparing two options: a standard chemotherapy called capecitabine combined w...

Not yet recruiting

Phase: PHASE3 Type: interventional Locations: Jinan, Shandong, China, Jinan, Shandong, China

MRI T1 Relaxation Time in Rectal Cancer

NCT ID: NCT05876026

This clinical trial is studying a specific imaging technique called MRI T1 relaxation time in people with locally advanced rectal cancer. The main goal of the study is to see how well this MRI meth...

Type: observational Locations: Vejle, Jylland, Denmark

Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors

NCT ID: NCT06239194

This clinical trial is testing a new treatment called MDX2001 for patients with advanced solid tumors, which are cancers that form in organs or tissues, such as breast, lung, or colorectal cancer. ...

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, Nashville, Tennessee, United States +4 more

PET/MRI in Rectal Cancer

NCT ID: NCT06057831

This clinical trial, called "PET/MRI in Rectal Cancer," aims to find out how well patients respond to treatment for rectal cancer by using a special imaging technique called PET/MRI after they have...

Not yet recruiting

Phase: PHASE2 Type: interventional

A Study of Fruquintinib Plus FOLFIRI as Second-Line Treatment for Participants With Metastatic Colorectal Cancer (mCRC)

NCT ID: NCT07011576

This clinical trial is studying a new treatment approach for patients with metastatic colorectal cancer (mCRC), which is cancer that has spread beyond the colon or rectum. The trial will test the c...

Not yet recruiting

Phase: PHASE2 Type: interventional

Organ Preservation First Strategy and Intentional Watch and Wait for MRI Defined Low-risk Rectal Cancer

NCT ID: NCT06209099

This clinical trial is looking at new ways to treat low-risk rectal cancer while preserving the organ. The main focus is to see if patients can safely undergo local excision (a type of surgery to r...

Phase: NA Type: interventional Locations: Beijing, Haidian District, China

Neoadjuvant Chemotherapy, Excision And Observation vs Chemoradiotherapy For Rectal Cancer

NCT ID: NCT06205485

This clinical trial is exploring two different treatment options for patients with rectal cancer. The study aims to find out if patients have a similar chance of their cancer responding to treatmen...

Phase: PHASE3 Type: interventional Locations: Chicago, Illinois, United States, Saskatoon, Saskatchewan, Canada +67 more

Improving Nutrition and Physical Activity for Cancer Survivors (Tools To Be Fit)

NCT ID: NCT05056077

This clinical trial, called "Tools To Be Fit," is exploring how different support tools can help cancer survivors improve their nutrition, physical activity, and overall health after treatment. Res...

Phase: NA Type: interventional Locations: Boston, Massachusetts, United States, San Francisco, California, United States

Integrated Cancer Repository for Cancer Research

NCT ID: NCT02012699

The Integrated Cancer Repository for Cancer Research (iCaRe2) is a study designed to gather important information and samples from adults who have been diagnosed with cancer, those at high risk for...

Type: observational Locations: Pittsburgh, Pennsylvania, United States, Denver, Colorado, United States +93 more

A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression

NCT ID: NCT06682793

This clinical trial is testing a new treatment called A2B395 for patients with certain types of solid tumors, such as colorectal cancer, lung cancer, and triple-negative breast cancer. The main goa...

Phase: PHASE1 Type: interventional Locations: Rochester, Minnesota, United States, St. Louis, Missouri, United States +8 more

Contact Radiotherapy for Rectal Cancer

NCT ID: NCT06501053

The CORRECT clinical trial is studying a new treatment approach for patients with early-stage rectal cancer. Specifically, it aims to compare a combination of Contact X-ray Brachytherapy (CXB) and ...

Phase: NA Type: interventional Locations: Stockholm, Solna, Sweden, Uppsala, , Sweden

Non Inferiority Study of Preoperative Chemotherapy Without Pelvic Irradiation for Rectal Cancer

NCT ID: NCT03875781

This clinical trial is investigating a new approach to treating locally advanced rectal cancer. It compares two treatment strategies: one group of patients will receive preoperative chemotherapy al...

Phase: PHASE3 Type: interventional Locations: Le Kremlin Bicêtre, Ile De France, France

Predicting the Efficacy of Neoadjuvant Therapy in Patients With Locally Advanced Rectal Cancer Using an AI Platform Based on Multi-parametric MRI

NCT ID: NCT05523245

This clinical trial is studying how well a new artificial intelligence (AI) tool can predict how effective a treatment called neoadjuvant therapy will be for patients with locally advanced rectal c...

Type: observational Locations: Guangzhou, Guangdong, China, Guangzhou, Guangdong, China +2 more

A Study of Response to Standard Treatment Before Surgery in People With Rectal Cancer

NCT ID: NCT06637462

This clinical trial is studying how people with rectal cancer respond to standard treatments, which include a combination of chemotherapy and radiation before surgery. The goal is to understand how...

Phase: NA Type: interventional Locations: New York, New York, United States, Middletown, New Jersey, United States +4 more

Resilience and Equity in Aging, Cancer, and Health (REACH)

NCT ID: NCT04674267

The REACH trial is a research study that aims to find out how consulting with a specialized doctor for older adults, known as a geriatrician, can improve care for patients aged 70 and older who hav...

Phase: NA Type: interventional Locations: Boston, Massachusetts, United States

A Study of Tucatinib and Trastuzumab in People With Rectal Cancer

NCT ID: NCT05672524

This clinical trial is exploring the effects of two medications, tucatinib and trastuzumab, combined with standard chemotherapy, on patients with rectal cancer. Researchers believe that this combin...

Phase: PHASE2 Type: interventional Locations: Montvale, New Jersey, United States, Harrison, New York, United States +13 more

Selective Defunctioning Stoma in Low Anterior Resection for Rectal Cancer

NCT ID: NCT06214988

This clinical trial is investigating a specific approach to managing patients with rectal cancer who are undergoing a surgical procedure called low anterior resection. The goal is to determine whet...

Phase: NA Type: interventional Locations: Malmö, , Sweden

An Informational and Supportive Care Intervention for Patients With Locally Advanced Rectal Cancer

NCT ID: NCT05914766

This clinical trial is looking at a new way to support patients who have locally advanced rectal cancer, which means their cancer is at stage II or III and requires a combination of treatments. The...

Phase: NA Type: interventional Locations: Boston, Massachusetts, United States, Boston, Massachusetts, United States

Node-Sparing Short-Course Radiotherapy Sequential Chemotherapy and PD-1 Inhibitor for Mid/Low pMMR/MSS Rectal Cancer (MODIFI-RC-II)

NCT ID: NCT06958432

The MODIFI-RC-II clinical trial is studying a new treatment approach for patients with a specific type of rectal cancer known as mid/low microsatellite stable (MSS) or proficient mismatch repair (p...

Phase: PHASE2 Type: interventional Locations: Guangzhou, Guangdong, China

Brodalumab in the Treatment of Immune-Related Adverse Events

NCT ID: NCT06673329

This clinical trial is studying a medication called brodalumab to see if it can help manage side effects caused by cancer treatments that boost the immune system. These side effects, known as immun...

Phase: PHASE1 Type: interventional Locations: New York, New York, United States

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