Selective TrkA Inhibitor VMD-928 to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma

NCT ID: NCT03556228

This clinical trial is studying a new medication called VMD-928, which is being tested for patients with certain types of advanced cancers and lymphomas that have not responded to standard treatmen...

Recruiting

Phase: PHASE1 Type: interventional Locations: Milwaukee, Wisconsin, United States, Duarte, California, United States +32 more

SLV-154 Treatment of Metastatic Solid Tumors

NCT ID: NCT06771219

This clinical trial is studying a new treatment called SLV-154 for patients with certain types of metastatic solid tumors, which are cancers that have spread from their original site to other parts...

Recruiting

Phase: PHASE1 Type: interventional Locations: St. Louis, Missouri, United States, Saint Louis, Missouri, United States +2 more

A Trial of ABSK043, an Oral PD-L1 Inhibitor, in Patients With Angiogenic Sarcomas

NCT ID: NCT07014137

This clinical trial is studying a new experimental drug called ABSK043, which works by blocking a protein known as PD-L1. This protein is important for regulating how the immune system responds to ...

Not yet recruiting

Phase: PHASE2 Type: interventional Locations: Toronto, Ontario, Canada

BOLD-100 Plus Doxorubicin in Advanced Soft Tissue Sarcomas

NCT ID: NCT07027423

This clinical trial is testing a new treatment combination for people with advanced soft tissue sarcomas, a type of cancer that starts in the soft tissues like muscles or fat. The study is looking ...

Not yet recruiting

Phase: PHASE1 Type: interventional Locations: Toronto, Ontario, Canada

Phase I Trial of TURALIO(R) (Pexidartinib, PLX3397) in Children and Young Adults With Refractory Leukemias and Refractory Solid Tumors Including Neurofibromatosis Type 1 (NF1) Associated Plexiform Neurofibromas (PN) and Tenosynovial Giant Cell Tumor ...

NCT ID: NCT02390752

This clinical trial is studying a medication called TURALIO® (pexidartinib) to see if it can help shrink or stop the growth of certain types of cancer in children and young adults aged 3 to 35. The...

Recruiting

Phase: PHASE1 Type: interventional Locations: Bethesda, Maryland, United States, Bethesda, Maryland, United States

Symptom Management and Transitioning to Engagement With Post-treatment Care for Adolescent and Young Adult Cancer Survivors

NCT ID: NCT06371768

This clinical trial is studying a digital health program called AYA STEPS, which aims to help young people aged 15 to 39 who have survived certain types of cancer, such as breast cancer, colorectal...

Recruiting

Phase: NA Type: interventional Locations: Durham, North Carolina, United States

HTL0039732 in Participants With Advanced Solid Tumours

NCT ID: NCT05944237

This clinical trial is studying a new drug called HTL0039732 to see how it works for people with advanced solid tumors, which are types of cancer that form in various organs, like the prostate, sto...

Recruiting

Phase: PHASE1 Type: interventional Locations: London, , United Kingdom, Cambridge, , United Kingdom +3 more

Integrated Cancer Repository for Cancer Research

NCT ID: NCT02012699

The Integrated Cancer Repository for Cancer Research (iCaRe2) is a study designed to gather important information and samples from adults who have been diagnosed with cancer, those at high risk for...

Recruiting

Type: observational Locations: Pittsburgh, Pennsylvania, United States, Denver, Colorado, United States +93 more

Trial of Selumetinib and Bromodomain Inhibitor With Durvalumab for Sarcomas

NCT ID: NCT05253131

This clinical trial is investigating a new treatment approach for certain types of sarcomas, specifically focusing on a combination of three drugs: selumetinib, a bromodomain inhibitor (BI), and du...

Not yet recruiting

Phase: PHASE2 Type: interventional Locations: New York, New York, United States, Baltimore, Maryland, United States +14 more

A Checklist (Advanced Care Planning) for The Assessment of Mobility Needs in Patients With Sarcoma

NCT ID: NCT05835154

This clinical trial is looking at a special checklist that helps doctors understand the future mobility needs of patients with sarcoma, a type of cancer that affects the bones and soft tissues. The...

Not yet recruiting

Phase: NA Type: interventional Locations: Seattle, Washington, United States

A Phase 1, First-in-human Study of OKN4395 and Pembrolizumab in Patients With Solid Tumors

NCT ID: NCT06789172

This clinical trial is testing a new drug called OKN4395, both on its own and together with another medication called pembrolizumab, in patients with different types of solid tumors like sarcoma an...

Recruiting

Phase: PHASE1 Type: interventional Locations: Santa Monica, California, United States, Manchester, , United Kingdom +3 more

Study of All-Trans Retinoic Acid (ATRA) and Cemiplimab in Patients With Advanced Leiomyosarcoma

NCT ID: NCT06528769

This clinical trial is studying the combination of two medications, all-trans retinoic acid (ATRA) and Cemiplimab, to see how effective they are for patients with advanced leiomyosarcoma (LMS), a t...

Recruiting

Phase: PHASE2 Type: interventional Locations: Columbus, Ohio, United States

Palbociclib and Pembrolizumab in Sarcoma

NCT ID: NCT06113809

This clinical trial is studying the effects of two medications, palbociclib and pembrolizumab, in patients with a type of cancer called undifferentiated pleomorphic sarcoma (UPS). The goal is to se...

Recruiting

Phase: PHASE1 Type: interventional Locations: Iowa City, Iowa, United States

A Study of Cabozantinib as a Maintenance Agent to Prevent Progression or Recurrence in High-Risk Pediatric Solid Tumors

NCT ID: NCT05135975

This clinical trial is exploring the use of a medication called cabozantinib as a maintenance treatment for children and young adults with high-risk solid tumors, specifically neuroblastoma and sar...

Recruiting

Phase: PHASE2 Type: interventional Locations: Washington, District Of Columbia, United States, Columbus, Ohio, United States +4 more

FIH, Bispecific CD276xCD3 Antibody CC-3 in Patients With Colorectal Cancer

NCT ID: NCT05999396

This clinical trial is studying a new treatment called CC-3 for patients with colorectal cancer that has not responded to at least three previous therapies. CC-3 is a special type of medicine known...

Recruiting

Phase: PHASE1 Type: interventional Locations: Tuebingen, Baden Wuerttemberg, Germany

A Study of Radiation Therapy to Treat Solid Tumor Cancer That Has Spread to Soft Tissue

NCT ID: NCT05837767

This clinical trial is investigating a new type of radiation therapy called lattice radiation therapy (LRT) to see if it works better than the standard approach known as stereotactic body radiation...

Recruiting

Phase: NA Type: interventional Locations: New York, New York, United States, Harrison, New York, United States +5 more

Bone Arches: Performance of Pseudo-scanner Sequences in Segmenting the Extent of the Tumour and in Planning Surgical Resection Using the CT Scan as a Reference

NCT ID: NCT06988007

This clinical trial, called "Bone Arches," is investigating a new type of MRI scan called "pseudo-scanner" sequences to see how well it can help identify the size and location of bone tumors, speci...

Not yet recruiting

Phase: NA Type: interventional Locations: Brussels, , Belgium, Brussels, , Belgium

A Study of Pembrolizumab Plus Local Chemotherapy Using Isolated Limb Infusion (ILI) for Patients With Sarcoma in the Arm or Leg

NCT ID: NCT04332874

This clinical trial is studying a treatment approach for patients with certain types of sarcoma, a type of cancer that affects soft tissues. The study is looking at a combination of a drug called p...

Recruiting

Phase: PHASE2 Type: interventional Locations: New York, New York, United States, New York, New York, United States +9 more

Study Assessing the Effects of Early Psychiatric Referral on Mental Health and Quality of Life in People With Sarcoma

NCT ID: NCT06129903

This clinical trial is studying how early access to mental health care can affect the overall well-being of patients with sarcoma, which is a type of cancer that can occur in bones or soft tissues....

Recruiting

Phase: NA Type: interventional Locations: Harrison, New York, United States, Montvale, New Jersey, United States +7 more

Acupuncture as add-on to G-CSF for Febrile Neutropenia-related Hospitalization in Doxorubicin-treated Patients With Sarcoma

NCT ID: NCT06500715

This clinical trial is studying whether acupuncture can help patients with sarcoma who are undergoing chemotherapy with doxorubicin, particularly to prevent a serious side effect called febrile neu...

Not yet recruiting

Phase: NA Type: interventional Locations: Jerusalem, , Israel

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Clinical Trials for Sarcoma

133 Active Trials Found

Selective TrkA Inhibitor VMD-928 to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma

SLV-154 Treatment of Metastatic Solid Tumors

A Trial of ABSK043, an Oral PD-L1 Inhibitor, in Patients With Angiogenic Sarcomas

BOLD-100 Plus Doxorubicin in Advanced Soft Tissue Sarcomas

Phase I Trial of TURALIO(R) (Pexidartinib, PLX3397) in Children and Young Adults With Refractory Leukemias and Refractory Solid Tumors Including Neurofibromatosis Type 1 (NF1) Associated Plexiform Neurofibromas (PN) and Tenosynovial Giant Cell Tumor ...

Symptom Management and Transitioning to Engagement With Post-treatment Care for Adolescent and Young Adult Cancer Survivors

HTL0039732 in Participants With Advanced Solid Tumours

Integrated Cancer Repository for Cancer Research

Trial of Selumetinib and Bromodomain Inhibitor With Durvalumab for Sarcomas

A Checklist (Advanced Care Planning) for The Assessment of Mobility Needs in Patients With Sarcoma

A Phase 1, First-in-human Study of OKN4395 and Pembrolizumab in Patients With Solid Tumors

Study of All-Trans Retinoic Acid (ATRA) and Cemiplimab in Patients With Advanced Leiomyosarcoma

Palbociclib and Pembrolizumab in Sarcoma

A Study of Cabozantinib as a Maintenance Agent to Prevent Progression or Recurrence in High-Risk Pediatric Solid Tumors

FIH, Bispecific CD276xCD3 Antibody CC-3 in Patients With Colorectal Cancer

A Study of Radiation Therapy to Treat Solid Tumor Cancer That Has Spread to Soft Tissue

Bone Arches: Performance of Pseudo-scanner Sequences in Segmenting the Extent of the Tumour and in Planning Surgical Resection Using the CT Scan as a Reference

A Study of Pembrolizumab Plus Local Chemotherapy Using Isolated Limb Infusion (ILI) for Patients With Sarcoma in the Arm or Leg

Study Assessing the Effects of Early Psychiatric Referral on Mental Health and Quality of Life in People With Sarcoma

Acupuncture as add-on to G-CSF for Febrile Neutropenia-related Hospitalization in Doxorubicin-treated Patients With Sarcoma

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