Clinical Trials for Sepsis

Emapalumab Treatment For Anticipated Clinical Benefit In Sepsis Driven By The Interferon-Gamma Endotype (The EMBRACE Trial)

NCT ID: NCT06694701

The EMBRACE Trial is a research study looking at a new treatment called emapalumab for patients with sepsis, which is a serious infection that can affect the whole body. This trial will be conducte...

Candidemia in Critically Ill Patients

NCT ID: NCT06929494

This clinical trial is studying a serious condition called candidemia, which is a type of bloodstream infection caused by a fungus. This infection is particularly concerning for patients in intensi...

Effect of Remazolam Besylate Combined With Remifentanil Analgesic Sedation on the Prognosis of Patients With Sepsis

NCT ID: NCT06731088

Stratifying Critically Ill Patients for Novel Ferroptosis or Pyroptosis Intervention Strategies

NCT ID: NCT06928649

This clinical trial is looking at how certain biological processes, specifically ferroptosis (a type of cell death related to iron), might contribute to organ failure in critically ill patients. Wh...

Rapid Recognition of Corticosteroid Resistant or Sensitive Sepsis

NCT ID: NCT04280497

This clinical trial is studying the effects of two medications, hydrocortisone and fludrocortisone, compared to a placebo (a non-active treatment) in adults with sepsis, a serious condition caused ...

Comparison Between Interleukin 6 and Procalcitonin in Detecting Sepsis and Incidence of Mortality in Burn ICU Patients

NCT ID: NCT06915974

This clinical trial is studying how well a substance called Interleukin-6 (IL-6) works compared to another substance called procalcitonin in identifying sepsis in burn patients. Sepsis is a serious...

Shenfu Injection Modulates Carotid Elasticity in Septic Shock

NCT ID: NCT06915506

This clinical trial is exploring whether Shenfu Injection, a traditional Chinese herbal medicine, can help improve blood vessel health in patients experiencing septic shock, a serious condition tha...

A Phase III, Open Label, Randomized, Controlled Study of VBI-S in the Treatment of Hypovolemia in Patients With Septic Shock (VBI-S-02)

NCT ID: NCT06072430

This clinical trial, called VBI-S-02, is investigating a new treatment called VBI-S for patients suffering from septic shock, a serious condition caused by infections that can lead to dangerously l...

Stop Sepsis Through Home Monitoring Cooperative

NCT ID: NCT06920979

The "Stop Sepsis Through Home Monitoring Cooperative" clinical trial is studying a new way to monitor patients who have severe infections and are at risk of developing a serious condition called se...

Immunomodulatory Effects of Dexamethasone, Tocilizumab and Anakinra During Experimental Human Endotoxemia

NCT ID: NCT06624436

This clinical trial is studying the effects of three different medications—dexamethasone, tocilizumab, and anakinra—on the immune system during a controlled experiment that mimics a condition calle...

Novel Biomarkers Related Xuebijing Injection Improves Sepsis

NCT ID: NCT06920420

This clinical trial is studying a new treatment called hemopexin injection for patients with sepsis, a serious condition that happens when the body has a severe reaction to an infection, leading to...

Identification of Markers of Poor Clinical Prognosis in Sepsis by Epigenetic Analysis

NCT ID: NCT06446947

This clinical trial is looking to identify new markers that can help predict which patients with sepsis might develop more severe complications, specifically septic shock. Sepsis is a serious condi...

Evaluation of Pediatric eCART Implementation

NCT ID: NCT06771830

This clinical trial is studying a new tool called pediatric eCART, which helps healthcare providers identify children at high risk for serious health problems like cardiac arrest or sepsis. Researc...

Study on the Construction and Application of Early Warning Model of Sepsis in Critically Ill Patients

NCT ID: NCT06904001

Hemodynamic Evaluation Using Microcirculation for Early Treatment of Septic Patients

NCT ID: NCT06910891

This clinical trial is studying how measuring small blood vessel function (microcirculation) can help doctors treat patients with sepsis more effectively. Sepsis is a serious condition that occurs ...

Correlation of Memory CD8+ T Cells With Sepsis Severity and Mortality: a Single-center, Unblinded, Prospective, Non-interventional, Observational Study

NCT ID: NCT05875740

This clinical trial is studying how certain types of immune cells, called CD8+ T cells, relate to the severity of sepsis and the chances of recovery in patients in the intensive care unit (ICU). Se...

NeoDoppler: New Ultrasound Technology for Continuous Monitoring of Cerebral Circulation Pilot

NCT ID: NCT06646250

The NeoDoppler trial is studying a new ultrasound technology that helps doctors continuously monitor blood flow to the brain in very sick newborns and premature infants. This is important because u...

Limited Versus Extended Trophic Feeding (LET-FEED) Trial

NCT ID: NCT06893939

The LET-FEED Trial is a research study designed to see if starting feeding earlier (after 24 hours of birth) for very preterm infants can help reduce the risk of infections (specifically late-onset...

Efficacy of SGLT2 Inhibitors in Adults With Sepsis

NCT ID: NCT06473844

This clinical trial is studying the effect of a type of medication called SGLT2 inhibitors on adults who are experiencing sepsis, a serious condition caused by an infection that can lead to organ f...

Prognostic Value of Right Ventricular-pulmonary Arterial Coupling Assessed by Echocardiography in Septic Patients

NCT ID: NCT06887140

This clinical trial is studying how well the right side of the heart works in patients with sepsis, a serious infection that can cause organ failure. The researchers want to see if measuring the re...