Clinical Trials for Sickle Cell Anemia

Hydroxyurea Exposure Limiting Pregnancy and Follow-Up Lactation

NCT ID: NCT04093986

This clinical trial is exploring how exposure to a medication called hydroxyurea affects women with sickle cell disease (SCD) during pregnancy and breastfeeding, as well as how it impacts their bab...

Blood Sampling for Research Related to Sickle Cell Disease

NCT ID: NCT00542230

This clinical trial is focused on studying sickle cell disease, a condition that affects how red blood cells work and limits their ability to carry oxygen in the body. Researchers want to collect b...

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Pociredir

NCT ID: NCT05169580

This clinical trial is studying a new treatment called FTX-6058 for people with sickle cell disease, a condition that causes severe pain and other health issues. The main goals of the study are to ...

Feasibility and Preliminary Efficacy of Acceptance and Commitment Therapy (ACT) for Sleep Disturbances in Adults With Sickle Cell Disease (SCD)

NCT ID: NCT05457790

This clinical trial is exploring how effective Acceptance and Commitment Therapy (ACT) can be for adults with sickle cell disease (SCD) who have trouble sleeping. ACT is a type of therapy that help...

Evaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell Disease

NCT ID: NCT05477563

This clinical trial is studying a new treatment called CTX001 for people with transfusion-dependent β-thalassemia (TDT) or severe sickle cell disease (SCD). The treatment involves modifying a patie...

Pressure Pain Tolerance in Relation to Balance and Strength in Children

NCT ID: NCT06529874

This clinical trial is studying how pain tolerance relates to balance and muscle strength in children with sickle cell anemia. Sickle cell anemia is a condition where the body produces abnormal red...

A Long-term Follow-up Study in Participants Who Received CTX001

NCT ID: NCT04208529

Awake Prone Positioning for Severe Acute Chest Syndrome

NCT ID: NCT06698120

This clinical trial is studying a method called Awake Prone Positioning (APP) to see if it can help people with severe acute chest syndrome (ACS), a serious condition that affects individuals with ...

Alendronate for Osteonecrosis in Adults With Sickle Cell Disease

NCT ID: NCT06016634

This clinical trial is studying the effects of a medication called alendronate on adults who have sickle cell disease and are experiencing a condition known as osteonecrosis. Osteonecrosis occurs w...

T-Cell Depleted Alternative Donor Bone Marrow Transplant for Sickle Cell Disease (SCD) and Other Anemias

NCT ID: NCT03653338

This clinical trial is studying a new type of bone marrow transplant for patients with severe sickle cell disease and other similar conditions, like beta-thalassemia and Diamond-Blackfan anemia. Th...

A Trial to Assess Haploidentical T-depleted Stem Cell Transplantation in Patients With SCD

NCT ID: NCT04201210

This clinical trial is exploring a new type of stem cell transplant called haploidentical transplantation for patients with sickle cell disease (SCD). Sickle cell disease can cause many health issu...

Measures of Respiratory Health (MRH)

NCT ID: NCT02657837

This clinical trial, called Measures of Respiratory Health (MRH), is studying how well the lungs work in patients with conditions like cystic fibrosis, asthma, sickle cell anemia, and bronchiolitis...

Bone Marrow and Kidney Transplant for Patients With Chronic Kidney Disease and Blood Disorders

NCT ID: NCT01758042

This clinical trial aims to explore the effects of a combined bone marrow and kidney transplant for patients with chronic kidney disease and certain blood disorders, such as leukemia and lymphoma. ...