Clinical Trials for Sickle Cell Disease

Sickle Cell, Pain and Mediterranean Diet

NCT ID: NCT06886477

This clinical trial is looking to understand how following a Mediterranean diet might affect pain levels in people with Sickle Cell Disease. The Mediterranean diet is rich in fruits, vegetables, wh...

Long-term Follow-up of Subjects with Sickle Cell Disease Treated with Ex Vivo Gene Therapy

NCT ID: NCT04628585

Pharmacokinetics, Efficacy and Safety of Twice Daily Dosing Regimen of Hydroxycarbamide Dispersible Tablets in Children With Sickle Cell Disease

NCT ID: NCT06578507

This clinical trial is studying the use of Hydroxycarbamide, a medication in the form of dispersible tablets, to see how well it works and how safe it is for children with Sickle Cell Disease, spec...

A Phase I/II Study of ITU512 in Healthy Participants and Patients With Sickle Cell Disease

NCT ID: NCT06546670

This clinical trial is studying a new treatment called ITU512 to see how safe it is and how well it might work for people with sickle cell disease (SCD), a condition that affects the blood. The stu...

Efficacy and Safety of Tocilizumab for Acute Chest Syndrome Treatment in Patients With Sickle Cell Disease

NCT ID: NCT06818266

This clinical trial is studying the effectiveness and safety of a medication called tocilizumab for treating acute chest syndrome in patients with sickle cell disease. Acute chest syndrome is a ser...

Allo HSCT for High Risk Hemoglobinopathies

NCT ID: NCT06872333

This clinical trial, called "Allo HSCT for High Risk Hemoglobinopathies," is studying a treatment called allogeneic hematopoietic stem cell transplantation (HSCT) for patients with serious blood di...

Cognitive Remediation Intervention to Prepare for Transition of Care

NCT ID: NCT05336201

This clinical trial, called the Cognitive Remediation Intervention to Prepare for Transition of Care, is focused on helping young people with sickle cell disease improve their thinking and coping s...

Sickle Cell Clinical Research and Intervention Program

NCT ID: NCT02098863

The Sickle Cell Clinical Research and Intervention Program (SCCRIP) is a clinical trial focused on understanding how sickle cell disease (SCD) affects the body over time, especially as patients tra...

Effect of Virtual Reality Technology for Pain Management of Vaso-Occlusive Crisis in Patients With Sickle Cell Disease

NCT ID: NCT03353584

This clinical trial is exploring the use of virtual reality (VR) technology to help manage pain in patients with sickle cell disease who are experiencing a painful condition known as a vaso-occlusi...

Stroke Prevention in Nigeria 2 Trial

NCT ID: NCT06526117

The Stroke Prevention in Nigeria 2 Trial is studying the use of hydroxyurea, a medication, to help prevent strokes in children with sickle cell anemia (SCA) who are at high risk. The trial is takin...

Study on Use of Omega-3 Fatty Acids to Improve Outcomes in Individuals With Sickle Cell Disease

NCT ID: NCT05758766

This clinical trial is investigating whether plant-based omega-3 fatty acids, which are found in certain foods like algae, can help improve health outcomes for people with sickle cell disease. Sick...

Opioid Prescribing in the Emergency Department for Sickle Cell Disease

NCT ID: NCT06835335

This clinical trial is looking at how emergency doctors prescribe pain relief, specifically opioids, to patients with sickle cell disease who come to the emergency room with severe abdominal pain. ...

Advancing Feasibility and Acceptability of Digital Cognitive Rehabilitation in Sickle Cell Disease

NCT ID: NCT06770010

This clinical trial is exploring a new approach to help young people with sickle cell disease improve their memory and attention skills. Specifically, it is testing a combination of digital memory ...

Zinc for Infection Prevention in Sickle Cell Anemia-2 (ZIPS-2)

NCT ID: NCT06561061

The Zinc for Infection Prevention in Sickle Cell Anemia-2 (ZIPS-2) trial is studying whether zinc supplements can help prevent serious infections in young children with sickle cell anemia in Uganda...

Optimizing the Management of Sickle Cell Patients on Hydroxyurea: The Value of Therapeutic Pharmacological Monitoring

NCT ID: NCT06464458

This clinical trial is studying how to better manage sickle cell disease in patients who are starting treatment with a medication called hydroxyurea. Sickle cell disease can cause painful episodes ...

A Long-term Follow-up Study in Participants Who Received CTX001

NCT ID: NCT04208529

Hematopoietic Stem Cell BCL11A Enhancer Gene Editing for Severe Β-Hemoglobinopathies

NCT ID: NCT06647979

This clinical trial is investigating a new type of treatment called gene therapy for serious blood disorders, specifically sickle cell disease and beta-thalassemia. In this trial, doctors will use ...

mAnaging siCkle CELl disEase Through incReased AdopTion of hydroxyurEa in Nigeria

NCT ID: NCT06318143

This clinical trial is focused on improving the use of hydroxyurea (HU) to treat sickle cell disease (SCD) in Nigeria. Sickle cell disease is a serious condition that affects many people in Nigeria...

Long-term Endurance Training in Sickle Cell Disease Patients: Impact on Clinical Profile, Physical Fitness, and Quality of Life.

NCT ID: NCT06823219

This clinical trial is studying the effects of long-term endurance training on patients with sickle cell disease (SCD), a condition that affects how blood cells function and can lead to pain and fa...

Integrative Medicine in Pain Management in Sickle Cell Disease

NCT ID: NCT05045820

This clinical trial is exploring how effective acupuncture can be in managing pain for people with sickle cell disease (SCD). Researchers want to understand not only if acupuncture helps reduce pai...