Clinical Trials for Total Knee Replacement

Mako Cementless TKA vs Mako Cemented TKA

NCT ID: NCT06929871

This clinical trial is looking at two different types of knee replacement surgeries: one that uses cement to secure the implant (called cemented TKA) and another that does not use cement (called ce...

Comparison of the Effects of Apixaban on Thrombin Generation in Patients With de Novo Multiple Myeloma

NCT ID: NCT06474182

This clinical trial, called APIXABOR, is studying how the medication Apixaban affects blood clotting in patients with multiple myeloma (a type of blood cancer) compared to patients undergoing total...

Persona IQ Cohort Study

NCT ID: NCT06089291

TRabecular Metal Economic and Clinical Knee Trial

NCT ID: NCT04677907

The TRabecular Metal Economic and Clinical Knee Trial is a study that aims to compare two types of total knee replacements: cemented and uncemented. Researchers want to see if there are differences...

Postural Correctors & Activity Trackers in Total Knee Replacement Rehab

NCT ID: NCT06877845

This clinical trial is looking at how two types of devices, postural correctors and activity trackers, can help people recover after total knee replacement surgery. The study aims to see if using a...

Yale Steroid Enhanced Versus Exparel Nerveblock TKA Part 2

NCT ID: NCT05736549

The Yale Steroid Enhanced Versus Exparel Nerveblock trial is studying two different pain management methods for patients undergoing bilateral total knee replacement surgery. The researchers want to...

Yale Steroid Enhanced Versus Exparel Nerveblock TKA RCT Study

NCT ID: NCT05279092

The Yale Steroid Enhanced Versus Exparel Nerveblock study is looking at two different methods to help manage pain after total knee replacement surgery. Researchers want to see whether a combination...

Movement Dynamics of Knee Osteoarthritis and Total Knee Replacement

NCT ID: NCT06829433

This clinical trial is studying how knee osteoarthritis (OA) affects walking and movement compared to people who have had total knee replacement surgery and healthy individuals. The researchers wan...

Comparison of Pivotal Medial Polyethylene Versus Ultra-congruent in Total Knee Arthroplasty

NCT ID: NCT06676189

This clinical trial is studying two different types of materials used in total knee replacement surgery: medial pivot polyethylene and ultra-congruent polyethylene. The goal is to see which materia...

Genicular and Anterior Femoral Cutaneous Nerve Blocks for Total Knee Arthroplasty

NCT ID: NCT05980546

This clinical trial is studying the effects of two specific nerve blocks, called the genicular nerve block and the anterior femoral cutaneous nerve block, on pain management and opioid use in patie...

Metal Ion Concentrations After Total Knee Arthroplasty

NCT ID: NCT06447922

This clinical trial is looking at the levels of metal ions in the blood of patients after they have undergone total knee replacement surgery. There are two types of surgeries being compared: one th...

Effects of Fall Prevention Program on the Number of Falls Among Elderly Following Total Knee Replacement

NCT ID: NCT05642260

This clinical trial is looking at how a special program designed to prevent falls can help older women who have recently had total knee replacement (TKR) surgery. The researchers want to see if com...

Remote Multichannel Monitoring of Patients With Chronic DIseAses Using Speech technoLogies Based On Artificial intelliGence

NCT ID: NCT06644339

The DIALOG study is looking at how well a new remote monitoring system works for patients with chronic diseases like heart failure, diabetes, and high blood pressure after they leave the hospital. ...

A Post-market Observational ORIGIN® CR Clinical Study

NCT ID: NCT05607966

This clinical trial is studying the safety and effectiveness of a specific type of knee replacement device called the ORIGIN® CR (cruciate retaining) prosthesis. Researchers want to see how well th...

The Effect of Abdominal Massage and Warm Application on Excretory Activity in Patients Undergoing Total Knee Replacement With Spinal Anesthesia

NCT ID: NCT06578936

This clinical trial is looking at how abdominal massage and warm applications can help with bowel movements in patients who are undergoing total knee replacement surgery with spinal anesthesia. Aft...

A Study to Compare Different Ways of Steroid Administration After Total Knee Implantation

NCT ID: NCT04432012

This clinical trial is looking at different ways to give steroid medications to patients who are having a total knee replacement surgery. The researchers want to find out if giving steroids through...

Knee4Life Project: Empowering Knee Recovery After Total Knee Replacement Through Digital Health

NCT ID: NCT06429462

The Knee4Life Project is a research study designed to help people recover better after total knee replacement (TKR) surgery, which is a common procedure in the UK. The study will explore whether a ...

Tapentadol vs Tramadol in Total Knee Arthroplasty

NCT ID: NCT06269770

This clinical trial is investigating how effective two pain medications, tapentadol and tramadol, are for patients who are undergoing total knee replacement surgery. The study aims to see which of ...

Knee Arthroplasty Activity Trial

NCT ID: NCT04107649

The Knee Arthroplasty Activity Trial (KArAT) is studying ways to help people who have had total knee replacement surgery become more physically active after their operation. Although knee replaceme...

Effect of Mindfulness on Pain After Total Knee Arthroplasty

NCT ID: NCT06118073