Clinical Trials in Huntsville, Alabama

Clinical and Genetic Evaluation of Individuals With Undiagnosed Disorders Through the Undiagnosed Diseases Network

NCT ID: NCT02450851

This clinical trial, called the Undiagnosed Diseases Network (UDN), is focused on helping individuals who have mysterious health conditions that doctors have not been able to diagnose. Many patient...

A Study of Galcanezumab (LY2951742) in Participants 6 to 17 Years of Age With Episodic Migraine

NCT ID: NCT03432286

This clinical trial is investigating a medication called galcanezumab to see how well it works in preventing episodic migraines in children and teenagers aged 6 to 17 years. The main goal is to fin...

A Study of Galcanezumab (LY2951742) in Participants 12 to 17 Years of Age With Chronic Migraine

NCT ID: NCT04616326

This clinical trial is studying a medication called galcanezumab to see if it can help prevent chronic migraines in teenagers aged 12 to 17. Chronic migraines are defined as having headaches that o...

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

NCT ID: NCT06119581

This clinical trial is investigating whether a new drug called LY3537982, combined with standard cancer treatments like immunotherapy and chemotherapy, is more effective for patients with advanced ...

EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)

NCT ID: NCT06531824

The EASi-KIDNEY™ trial is studying a new medicine called BI 690517 to see if it helps people with chronic kidney disease, especially when taken together with another medicine called empagliflozin. ...

Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer

NCT ID: NCT06890598

This clinical trial is studying a new treatment called olomorasib, which is being tested alongside standard treatments for patients with a specific type of lung cancer known as KRAS G12C-mutant non...

A Donanemab (LY3002813) Study in Participants With Preclinical Alzheimer's Disease (TRAILBLAZER-ALZ 3)

NCT ID: NCT05026866

The TRAILBLAZER-ALZ 3 study is a clinical trial focused on testing the safety and effectiveness of a drug called donanemab in people who have early signs of Alzheimer's disease but do not yet have ...

A Study of Imlunestrant Versus Standard Endocrine Therapy in Participants With Early Breast Cancer

NCT ID: NCT05514054

This clinical trial is studying a new treatment called imlunestrant to see how well it works compared to standard hormone therapy for patients with early breast cancer. The patients being considere...

ARTEMIS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With a Heart Attack

NCT ID: NCT06118281

The ARTEMIS clinical trial is investigating a new medication called ziltivekimab, which researchers hope can help people who have recently had a heart attack. The goal is to see if ziltivekimab can...

Effect of Retatrutide Compared With Placebo in Participants With Type 2 Diabetes and Moderate or Severe Renal Impairment, With Inadequate Glycemic Control on Basal Insulin, With or Without Metformin and/or SGLT2 Inhibitor (TRANSCEND-T2D-3)

NCT ID: NCT06297603

This clinical trial, called TRANSCEND-T2D-3, is exploring the effectiveness and safety of a new medication called retatrutide for people with Type 2 diabetes who also have moderate or severe kidney...

The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Kidney Outcomes in Adults Living With Obesity (TRIUMPH-Outcomes)

NCT ID: NCT06383390

The TRIUMPH-OUTCOMES study is looking at a new treatment called retatrutide, which is given once a week, to see if it can help reduce serious heart problems and protect kidney function in adults wh...

ROADSTER 3 Extended Follow-up Sub-Study

NCT ID: NCT06470815

Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1- Mediated Proteinuric Kidney Disease

NCT ID: NCT05312879

This clinical trial is studying a new treatment called VX-147 for patients with a specific type of kidney disease known as APOL1-mediated proteinuric kidney disease. This condition can lead to prot...

A Study to Investigate Ataciguat for Slowing the Progression of Moderate Calcific Aortic Valve Stenosis

NCT ID: NCT07001800

This clinical trial is studying a medication called ataciguat to see if it can help slow down the worsening of a heart condition known as moderate calcific aortic valve stenosis (CAVS). This condit...

Observational Study Evaluating the Efficacy and Safety of Zanubrutinib in Participants With Waldenström Macroglobulinemia

NCT ID: NCT05640102

This clinical trial is studying the effectiveness and safety of a medication called zanubrutinib for patients with Waldenström Macroglobulinemia (WM), a type of blood cancer. The study aims to gath...

A Study of Milvexian in Participants After a Recent Acute Coronary Syndrome

NCT ID: NCT05754957

This clinical trial is studying a medication called milvexian to see if it can help reduce the risk of serious heart problems in patients who have recently experienced an acute coronary syndrome (A...

Evaluation of Efficacy of Povetacicept in Adults With Immunoglobulin A Nephropathy (IgAN)

NCT ID: NCT06564142

This clinical trial is studying a new medication called povetacicept for adults with Immunoglobulin A Nephropathy (IgAN), a condition that affects the kidneys and can lead to kidney damage. The mai...

A Study to Explore the Efficacy of JNJ-89495120 in the Treatment of Major Depressive Disorder

NCT ID: NCT06785012

This clinical trial is exploring a new treatment called JNJ-89495120 for people with major depressive disorder (MDD), a serious condition that affects mood and daily life. The study aims to see how...

A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

NCT ID: NCT06667076

This clinical trial is studying a new treatment for patients with a type of lung cancer called non-small cell lung cancer (NSCLC) that has specific genetic mutations known as EGFR mutations. The re...

A Study of Oral Atogepant Tablets to Assess Adverse Events and Change in Disease Activity To Prevent Migraine in Participants Aged 12 to 17 Years

NCT ID: NCT06810505

This clinical trial is studying a medication called atogepant to see how well it can help prevent chronic migraines in teenagers aged 12 to 17. Chronic migraines are severe headaches that can happe...