Clinical Trials in Mobile, Alabama

Find clinical trials in Mobile, Alabama. Discover local research opportunities and treatment options in your area.

139 Active Trials Found in Mobile

Showing 139 trials on this page

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Testing the Use of the Combination of Selumetinib and Olaparib or Selumetinib Alone Targeted Treatment for RAS Pathway Mutant Recurrent or Persistent Ovarian and Endometrial Cancers, A ComboMATCH Treatment Trial

NCT ID: NCT05554328

This clinical trial, called the ComboMATCH treatment trial, is studying a new way to treat certain types of ovarian and endometrial cancers. Specifically, the trial is comparing two treatments: one...

Recruiting

Phase: PHASE2 Conditions: Recurrent Ovarian Carcinoma, Recurrent Primary Peritoneal Carcinoma +2 more

ARTEMIS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With a Heart Attack

NCT ID: NCT06118281

The ARTEMIS clinical trial is investigating a new medication called ziltivekimab, which researchers hope can help people who have recently had a heart attack. The goal is to see if ziltivekimab can...

Recruiting

Phase: PHASE3 Conditions: Cardiovascular Risk, Acute Myocardial Infarction (AMI)

MagnetisMM-32: A Study to Learn About the Study Medicine Called Elranatamab in People With Multiple Myeloma (MM) That Has Come Back After Taking Other Treatments (Including Prior Treatment With an Anti-CD38 Antibody and Lenalidomide)

NCT ID: NCT06152575

The MagnetisMM-32 clinical trial is studying a new medicine called elranatamab for people with multiple myeloma (MM), a type of blood cancer that has returned after previous treatments. The trial a...

Recruiting

Phase: PHASE3 Conditions: Multiple Myeloma

Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)

NCT ID: NCT06393374

This clinical trial is studying a new treatment for patients with triple-negative breast cancer (TNBC) who did not completely respond to earlier treatment before surgery. The researchers want to fi...

Recruiting

Phase: PHASE3 Conditions: Triple-Negative Breast Cancer

A Study of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression

NCT ID: NCT07023627

This clinical trial is studying a new drug called INCB123667 for women with a type of ovarian cancer that has stopped responding to standard platinum-based chemotherapy. Specifically, it focuses on...

Recruiting

Phase: PHASE2 Conditions: Ovarian Cancer

A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event

NCT ID: NCT07000357

This clinical trial is studying a medication called AZD0780 to see if it can help reduce serious heart-related events in patients who have a history of cardiovascular disease or are at high risk fo...

Recruiting

Phase: PHASE3 Conditions: Cardiovascular Disease

A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab

NCT ID: NCT05675410

This clinical trial is studying whether adding two specific drugs, brentuximab vedotin and nivolumab, to the standard treatment for early-stage Hodgkin lymphoma can help patients live longer and ex...

Recruiting

Phase: PHASE3 Conditions: Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

NCT ID: NCT06172296

This clinical trial is studying a new treatment approach for children with high-risk neuroblastoma, a type of cancer that affects nerve cells. The researchers want to find out if combining a medici...

Recruiting

Phase: PHASE3 Conditions: Neuroblastoma, Ganglioneuroblastoma, Nodular

Comparison Between ABP 692 and Ocrevus® (Ocrelizumab)

NCT ID: NCT06700343

This clinical trial is comparing a new medication called ABP 692 to an existing treatment known as Ocrevus® (ocrelizumab) for patients with relapsing-remitting multiple sclerosis (RRMS). The main g...

Recruiting

Phase: PHASE3 Conditions: Relapsing-remitting Multiple Sclerosis (RRMS)

Evaluation of Maridebart Cafraglutide in Adult Participants Without Type 2 Diabetes Mellitus Who Have Obesity or Are Overweight

NCT ID: NCT06858839

This clinical trial is studying a medication called maridebart cafraglutide to see if it can help adults who are overweight or obese lose more weight compared to a placebo, which is an inactive tre...

Recruiting

Phase: PHASE3 Conditions: Obesity

Efficacy and Safety of Maridebart Cafraglutide in Adult Participants With Type 2 Diabetes Mellitus Who Have Obesity or Are Overweight

NCT ID: NCT06858878

This clinical trial is exploring a new medication called maridebart cafraglutide to see how effective it is for adults with type 2 diabetes who are also overweight or have obesity. The main goal is...

Recruiting

Phase: PHASE3 Conditions: Type 2 Diabetes Mellitus (T2DM), Obesity, Overweight

Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

NCT ID: NCT07037433

This clinical trial is studying a medicine called maridebart cafraglutide to see if it can help people with heart disease who are also overweight or obese. Specifically, the trial wants to find out...

Recruiting

Phase: PHASE3 Conditions: Obesity, Overweight +1 more

National Cancer Institute "Cancer Moonshot Biobank"

NCT ID: NCT04314401

The "Cancer Moonshot Biobank" is a clinical trial that aims to gather blood and tissue samples from patients diagnosed with various types of cancer, including advanced stages of breast cancer, lung...

Recruiting

Conditions: Multiple Myeloma, Melanoma +27 more

Palbociclib and Binimetinib in RAS-Mutant Cancers, A ComboMATCH Treatment Trial

NCT ID: NCT05554367

The clinical trial titled "Palbociclib and Binimetinib in RAS-Mutant Cancers" is investigating how effective a combination of two medications, palbociclib and binimetinib, can be for treating certa...

Recruiting

Phase: PHASE2 Conditions: Malignant Solid Neoplasm, Stage IV Pancreatic Cancer AJCC v8 +3 more

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

NCT ID: NCT05564377

The ComboMATCH Screening Trial is a study that aims to find effective treatments for patients with advanced solid tumors, such as certain types of breast cancer and other cancers that have spread e...

Recruiting

Phase: PHASE2 Conditions: Recurrent Ovarian Carcinoma, Metastatic Malignant Solid Neoplasm +13 more

Study of Chemotherapy, With or Without Binimetinib in Advanced Biliary Tract Cancers in 2nd Line Setting (A ComboMATCH Treatment Trial)

NCT ID: NCT05564403

This clinical trial, called the ComboMATCH treatment trial, is studying a new way to treat advanced biliary tract cancers, which include cancers of the bile ducts and gallbladder that have come bac...

Recruiting

Phase: PHASE2 Conditions: Stage III Intrahepatic Cholangiocarcinoma AJCC v8, Stage IV Intrahepatic Cholangiocarcinoma AJCC v8 +15 more

Testing the Use of AMG 510 (Sotorasib) and Panitumumab as a Targeted Treatment for KRAS G12C Mutant Solid Tumor Cancers (A ComboMATCH Treatment Trial)

NCT ID: NCT05638295

This clinical trial, called the ComboMATCH treatment trial, is studying a combination of two medications, AMG 510 (also known as sotorasib) and panitumumab, to see how well they work in treating ce...

Recruiting

Phase: PHASE2 Conditions: Metastatic Malignant Solid Neoplasm, Advanced Malignant Solid Neoplasm

A Multicentre, Randomised, Double-blind, Parallel Group, Placebo-controlled, Time-to-first Asthma Exacerbation Phase III Efficacy and Safety Study of Benralizumab in Paediatric Patients With Severe Eosinophilic Asthma (DOMINICA)

NCT ID: NCT05692180

The DOMINICA study is a clinical trial designed to evaluate the effectiveness and safety of a medication called benralizumab for children and teenagers aged 6 to 17 years who suffer from severe eos...

Recruiting

Phase: PHASE3 Conditions: Asthma

Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial)

NCT ID: NCT06126276

This clinical trial is investigating the effects of two treatments for patients with certain types of cancer known as HER2 positive solid tumors. The study compares a medication called neratinib to...

Recruiting

Phase: PHASE2 Conditions: Malignant Solid Neoplasm, Recurrent Malignant Solid Neoplasm +2 more

Study to Compare the Effectiveness and Safety of Golcadomide Plus R-CHOP vs Placebo Plus R-CHOP in Participants With Previously Untreated High-risk Large B-cell Lymphoma

NCT ID: NCT06356129

This clinical trial is studying a new treatment for patients with a type of cancer called high-risk large B-cell lymphoma (LBCL). Researchers want to see if adding a medication called golcadomide t...

Recruiting

Phase: PHASE3 Conditions: Large B-cell Lymphoma