Long-Term Follow-Up of Patients Who Have Participated in Children's Oncology Group Studies

NCT ID: NCT00736749

This clinical trial is focused on following up with patients who have been part of studies conducted by the Children's Oncology Group, which is a group that researches treatments for children's can...

Recruiting

Conditions: Leukemia, Solid Tumor +1 more

A Clinical Efficacy and Safety Study of OHB-607 in Preventing Bronchopulmonary Dysplasia in Extremely Premature Infants

NCT ID: NCT03253263

This clinical trial is studying a new medication called OHB-607, which aims to help prevent a serious lung condition known as Bronchopulmonary Dysplasia (BPD) in extremely premature infants. BPD is...

Recruiting

Phase: PHASE2 Conditions: Bronchopulmonary Dysplasia, Intraventricular Hemorrhage +2 more

A Study of Imlunestrant Versus Standard Endocrine Therapy in Participants With Early Breast Cancer

NCT ID: NCT05514054

This clinical trial is studying a new treatment called imlunestrant to see how well it works compared to standard hormone therapy for patients with early breast cancer. The patients being considere...

Recruiting

Phase: PHASE3 Conditions: Breast Neoplasms

Efficacy and Safety of Trimodulin (BT588) in Subjects With Severe Community-acquired Pneumonia (sCAP)

NCT ID: NCT05722938

This clinical trial is studying a new treatment called trimodulin (BT588) for adults with severe community-acquired pneumonia (sCAP) who are in the hospital and need help breathing with a machine (...

Recruiting

Phase: PHASE3 Conditions: Community-acquired Pneumonia

A Study to Investigate the Effect of Lepodisiran on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) - ACCLAIM-Lp(a)

NCT ID: NCT06292013

The ACCLAIM-Lp(a) trial is studying a new treatment called lepodisiran to see if it can help reduce the risk of serious heart problems in adults who have high levels of a substance called lipoprote...

Recruiting

Phase: PHASE3 Conditions: Elevated Lp(a), Atherosclerotic Cardiovascular Disease (ASCVD)

A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD

NCT ID: NCT06883305

This clinical trial is investigating the effectiveness and safety of a medication called Tezepelumab for adults with moderate to very severe Chronic Obstructive Pulmonary Disease (COPD). COPD is a ...

Recruiting

Phase: PHASE3 Conditions: Chronic Obstructive Pulmonary Disease (COPD)

A Phase III Study to Assess the Effect of AZD0780 on LDL-C in Patients With Clinical ASCVD or at Risk for a First ASCVD Event

NCT ID: NCT07000123

This clinical trial is studying a new medication called AZD0780, which is designed to lower levels of LDL cholesterol (often referred to as "bad" cholesterol) in the blood. The trial is for adults ...

Recruiting

Phase: PHASE3 Conditions: Cardiovascular Disease

Mirvetuximab Soravtansine With Bevacizumab Versus Bevacizumab as Maintenance in Platinum-sensitive Epithelial Ovarian, Fallopian Tube, or Peritoneal Cancer

NCT ID: NCT05445778

The GLORIOSA clinical trial is studying a new treatment approach for patients with certain types of ovarian, fallopian tube, or peritoneal cancer who have responded well to previous platinum-based ...

Recruiting

Phase: PHASE3 Conditions: Ovarian Cancer, Fallopian Tube Cancer +1 more

A Phase 2 Study of ACR-368 in Endometrial Adenocarcinoma

NCT ID: NCT05548296

This clinical trial is investigating a new treatment called ACR-368 for patients with certain types of cancer, specifically platinum-resistant ovarian cancer, endometrial adenocarcinoma, and urothe...

Recruiting

Phase: PHASE2 Conditions: Endometrial Adenocarcinoma

Study Of Oral Elagolix Tablets In Combination With Combined Oral Contraceptive Capsules/Tablets To Assess Dysmenorrhea Response In Adult Female Participants With Endometriosis And Associated Moderate To Severe Pain

NCT ID: NCT04333576

This clinical trial is studying a medication called elagolix, which is taken as a tablet, combined with birth control pills, to see how well it helps women with endometriosis manage their painful p...

Recruiting

Phase: PHASE3 Conditions: Endometriosis

The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Kidney Outcomes in Adults Living With Obesity (TRIUMPH-Outcomes)

NCT ID: NCT06383390

The TRIUMPH-OUTCOMES study is looking at a new treatment called retatrutide, which is given once a week, to see if it can help reduce serious heart problems and protect kidney function in adults wh...

Recruiting

Phase: PHASE3 Conditions: Chronic Kidney Disease (CKD), Atherosclerotic Cardiovascular Disease (ASCVD)

A Multicentre, Randomised, Double-blind, Parallel Group, Placebo-controlled, Time-to-first Asthma Exacerbation Phase III Efficacy and Safety Study of Benralizumab in Paediatric Patients With Severe Eosinophilic Asthma (DOMINICA)

NCT ID: NCT05692180

The DOMINICA study is a clinical trial designed to evaluate the effectiveness and safety of a medication called benralizumab for children and teenagers aged 6 to 17 years who suffer from severe eos...

Recruiting

Phase: PHASE3 Conditions: Asthma

53-Week Study Evaluating the Safety and Efficacy of Intra-articular Injections of TPX-100 With Mild to Severe Tibio-Femoral Osteoarthritis of the Knee

NCT ID: NCT06865079

This clinical trial is designed to evaluate the safety and effectiveness of a treatment called TPX-100, which is given through injections directly into the knee, for people suffering from osteoarth...

Recruiting

Phase: PHASE2 Conditions: Osteoarthritis (OA) of the Knee

Comparing Cisplatin Every Three Weeks to Cisplatin Weekly When Combined With Radiation for Patients With Advanced Head and Neck Cancer

NCT ID: NCT05050162

This clinical trial is studying two different ways of using a chemotherapy drug called cisplatin along with radiation therapy to treat patients with advanced head and neck cancer. The researchers w...

Recruiting

Phase: PHASE2 Conditions: Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8 +8 more

A Study to Evaluate How Well Etavopivat Works in People With Sickle Cell Disease

NCT ID: NCT06612268

This clinical trial is testing a new medication called etavopivat to see how well it helps people with sickle cell disease. Specifically, the study aims to find out if etavopivat can reduce painful...

Recruiting

Phase: PHASE3 Conditions: Sickle Cell Disease

Phase 2b Study of EVO756 in Adults With Moderate to Severe Chronic Spontaneous Urticaria (CSU)

NCT ID: NCT06873516

This clinical trial is looking at a new treatment called EVO756 for adults who have moderate to severe chronic spontaneous urticaria (CSU), a condition that causes itchy hives without a clear cause...

Recruiting

Phase: PHASE2 Conditions: Chronic Spontaneous Urticaria

A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing Loss

NCT ID: NCT05382338

This clinical trial is studying a potential treatment for children and young adults diagnosed with medulloblastoma, a type of brain cancer. The trial specifically looks at how sodium thiosulfate (S...

Recruiting

Phase: PHASE3 Conditions: Childhood Medulloblastoma

Proximal Internal Carotid Artery Acute Stroke Secondary to Tandem or Local Occlusion Thrombectomy Trial

NCT ID: NCT05611242

This clinical trial is studying a treatment for patients who have experienced an acute ischemic stroke, which is caused by a blockage in a blood vessel that supplies the brain. The trial aims to fi...

Recruiting

Phase: PHASE3 Conditions: Acute Ischemic Stroke

The Long-term Safety and Effectiveness Evaluation of the QDOT MICRO System Use in Conjunction With VISITAG SURPOINT Module for the Treatment of Symptomatic Drug Refractory Paroxysmal Atrial Fibrillation.

NCT ID: NCT06324201

This clinical trial is looking at the long-term safety and effectiveness of a specific treatment for patients with a type of irregular heartbeat called symptomatic drug refractory paroxysmal atrial...

Recruiting

Conditions: Paroxysmal Atrial Fibrillation

A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)

NCT ID: NCT04546399

This clinical trial is studying a new way to treat children and young adults who have a type of blood cancer called B-cell acute lymphoblastic leukemia (B-ALL) that has come back after initial trea...

Recruiting

Phase: PHASE2 Conditions: Down Syndrome, Recurrent B Acute Lymphoblastic Leukemia

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Clinical Trials in Mobile, Alabama

140 Active Trials Found in Mobile

Long-Term Follow-Up of Patients Who Have Participated in Children's Oncology Group Studies

A Clinical Efficacy and Safety Study of OHB-607 in Preventing Bronchopulmonary Dysplasia in Extremely Premature Infants

A Study of Imlunestrant Versus Standard Endocrine Therapy in Participants With Early Breast Cancer

Efficacy and Safety of Trimodulin (BT588) in Subjects With Severe Community-acquired Pneumonia (sCAP)

A Study to Investigate the Effect of Lepodisiran on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) - ACCLAIM-Lp(a)

A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD

A Phase III Study to Assess the Effect of AZD0780 on LDL-C in Patients With Clinical ASCVD or at Risk for a First ASCVD Event

Mirvetuximab Soravtansine With Bevacizumab Versus Bevacizumab as Maintenance in Platinum-sensitive Epithelial Ovarian, Fallopian Tube, or Peritoneal Cancer

A Phase 2 Study of ACR-368 in Endometrial Adenocarcinoma

Study Of Oral Elagolix Tablets In Combination With Combined Oral Contraceptive Capsules/Tablets To Assess Dysmenorrhea Response In Adult Female Participants With Endometriosis And Associated Moderate To Severe Pain

The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Kidney Outcomes in Adults Living With Obesity (TRIUMPH-Outcomes)

A Multicentre, Randomised, Double-blind, Parallel Group, Placebo-controlled, Time-to-first Asthma Exacerbation Phase III Efficacy and Safety Study of Benralizumab in Paediatric Patients With Severe Eosinophilic Asthma (DOMINICA)

53-Week Study Evaluating the Safety and Efficacy of Intra-articular Injections of TPX-100 With Mild to Severe Tibio-Femoral Osteoarthritis of the Knee

Comparing Cisplatin Every Three Weeks to Cisplatin Weekly When Combined With Radiation for Patients With Advanced Head and Neck Cancer

A Study to Evaluate How Well Etavopivat Works in People With Sickle Cell Disease

Phase 2b Study of EVO756 in Adults With Moderate to Severe Chronic Spontaneous Urticaria (CSU)

A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing Loss

Proximal Internal Carotid Artery Acute Stroke Secondary to Tandem or Local Occlusion Thrombectomy Trial

The Long-term Safety and Effectiveness Evaluation of the QDOT MICRO System Use in Conjunction With VISITAG SURPOINT Module for the Treatment of Symptomatic Drug Refractory Paroxysmal Atrial Fibrillation.

A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)