Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7

NCT ID: NCT04613596

The KRYSTAL-7 trial is studying a new treatment for patients with advanced non-small cell lung cancer (NSCLC) that has a specific mutation called KRAS G12C. The trial has two parts: the Phase 2 par...

Recruiting

Phase: PHASE2 Conditions: Advanced Non-Small Cell Lung Cancer, Metastatic Non-Small Cell Lung Cancer

A Study of Bomedemstat (IMG-7289/MK-3543) Compared to Best Available Therapy (BAT) in Participants With Essential Thrombocythemia and an Inadequate Response or Intolerance of Hydroxyurea (MK-3543-006)

NCT ID: NCT06079879

This clinical trial is studying a new medication called bomedemstat (also known as MK-3543) to see if it works better than the best available treatments for people with essential thrombocythemia (E...

Recruiting

Phase: PHASE3 Conditions: Essential Thrombocythemia

A Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011)

NCT ID: NCT06841354

This clinical trial is studying the effectiveness of a drug called sacituzumab tirumotecan (also known as Sac-TMT) both on its own and in combination with another drug called pembrolizumab for trea...

Recruiting

Phase: PHASE3 Conditions: Triple Negative Breast Neoplasms

Randomized Study in Children and Adolescents With Migraine: Acute Treatment

NCT ID: NCT04649242

This clinical trial is looking at a new treatment called BHV-3000 for children and teenagers who suffer from moderate or severe migraines. The study aims to see if this medication is safe and effec...

Recruiting

Phase: PHASE3 Conditions: Pediatric Migraine

Program to Assess Adverse Events and Change in Disease Activity of Oral Upadacitinib in Adult Participants With Moderate to Severe Systemic Lupus Erythematosus

NCT ID: NCT05843643

This clinical trial is studying the safety and effectiveness of a medication called upadacitinib for adults with moderate to severe systemic lupus erythematosus (SLE), a disease that causes inflamm...

Recruiting

Phase: PHASE3 Conditions: Systemic Lupus Erythematosus

A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)

NCT ID: NCT05920356

This clinical trial, called CodeBreaK 202, is studying two different treatments for patients with advanced non-small cell lung cancer (NSCLC) that has a specific genetic mutation known as KRAS p. G...

Recruiting

Phase: PHASE3 Conditions: Non-Small Cell Lung Cancer (NSCLC)

Long-Term Safety Study of Deucravacitinib Versus Ustekinumab in Participants With Psoriasis (PRAGMATYK)

NCT ID: NCT07116967

This clinical trial is studying the long-term safety of two medicines, Deucravacitinib and Ustekinumab, in people with moderate-to-severe plaque psoriasis, a common skin condition that causes red, ...

Not yet recruiting

Phase: PHASE3 Conditions: Plaque Psoriasis

Clinical Trial of TQB2102 for Injection Versus Trastuzumab Emtansine for Injection in HER2-positive Advanced Breast Cancer

NCT ID: NCT07008976

This clinical trial is studying a new treatment called TQB2102 for patients with advanced breast cancer that tests positive for a protein called HER2. This type of breast cancer can be more aggress...

Recruiting

Phase: PHASE3 Conditions: Metastatic Breast Cancer

A Study to Assess Effectiveness and Safety of Deucravacitinib Compared With Placebo in Participants With Active Systemic Lupus Erythematosus (SLE)

NCT ID: NCT05617677

This clinical trial is studying a medication called deucravacitinib to see how well it works and how safe it is for people with moderate to severe Systemic Lupus Erythematosus (SLE), a condition th...

Recruiting

Phase: PHASE3 Conditions: Systemic Lupus Erythematosus

A Study of Zasocitinib in Adults With Psoriatic Arthritis Who Have or Have Not Been Treated With Biologic Medicines

NCT ID: NCT06671496

This clinical trial is studying a new medication called zasocitinib (also known as TAK-279) to see how well it works for adults with psoriatic arthritis (PsA). PsA is a long-term condition that cau...

Recruiting

Phase: PHASE3 Conditions: Psoriatic Arthritis

TQB2930 Injection for the Treatment of HER2-positive Advanced Breast Cancer

NCT ID: NCT07047365

This clinical trial is studying a new drug called TQB2930, combined with chemotherapy, to treat advanced breast cancer that tests positive for a protein called HER2. The study will compare this new...

Recruiting

Phase: PHASE3 Conditions: HER2-positive Advanced Breast Cancer

A Study of LUCAR-G79 in Subjects With Relapsed/Refractory Autoimmune Diseases

NCT ID: NCT07049081

This clinical trial is testing a new treatment called LUCAR-G79 for adults with certain autoimmune diseases that have returned or not responded to previous treatments. Autoimmune diseases happen wh...

Recruiting

Phase: PHASE1 Conditions: Relapsed/Refractory Autoimmune Diseases

A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)

NCT ID: NCT06875310

The KRYSTAL-4 trial is studying a new treatment approach for patients with a specific type of lung cancer called non-small cell lung cancer (NSCLC) that has a mutation known as KRAS G12C. This tria...

Recruiting

Phase: PHASE3 Conditions: Carcinoma, Non-Small-Cell Lung

A Study of LUCAR-DKS1 in Subjects With Relapsed/Refractory Autoimmune Diseases

NCT ID: NCT07095075

This clinical trial is studying a new treatment called LUCAR-DKS1 for adults who have certain autoimmune diseases that have not improved with previous treatments or have come back after treatment. ...

Not yet recruiting

Phase: EARLY_PHASE1 Conditions: Relapsed/Refractory Autoimmune Diseases

A Study of Imlunestrant Versus Standard Endocrine Therapy in Participants With Early Breast Cancer

NCT ID: NCT05514054

This clinical trial is studying a new treatment called imlunestrant to see how well it works compared to standard hormone therapy for patients with early breast cancer. The patients being considere...

Recruiting

Phase: PHASE3 Conditions: Breast Neoplasms

Mirvetuximab Soravtansine With Bevacizumab Versus Bevacizumab as Maintenance in Platinum-sensitive Epithelial Ovarian, Fallopian Tube, or Peritoneal Cancer

NCT ID: NCT05445778

The GLORIOSA clinical trial is studying a new treatment approach for patients with certain types of ovarian, fallopian tube, or peritoneal cancer who have responded well to previous platinum-based ...

Recruiting

Phase: PHASE3 Conditions: Ovarian Cancer, Fallopian Tube Cancer +1 more

A Study of DB-1303/BNT323 vs Investigator's Choice Chemotherapy in HER2-Low, Hormone Receptor Positive Metastatic Breast Cancer (DYNASTY-Breast02)

NCT ID: NCT06018337

This clinical trial, called DYNASTY-Breast02, is looking at a new treatment option for patients with a specific type of metastatic breast cancer, which is cancer that has spread beyond the breast. ...

Recruiting

Phase: PHASE3 Conditions: Metastatic Breast Cancer

A Study of Lebrikizumab (LY3650150) in Adult Participants With Chronic Rhinosinusitis and Nasal Polyps Treated With Intranasal Corticosteroids (CONTRAST-NP)

NCT ID: NCT06338995

The CONTRAST-NP clinical trial is studying a medication called lebrikizumab to see how well it works and how safe it is for adults with chronic rhinosinusitis and nasal polyps. This condition can c...

Recruiting

Phase: PHASE3 Conditions: Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)

Study of SLS009 (Formerly GFH009) a Potent Highly Selective CDK9 Inhibitor in Patients With Hematologic Malignancies

NCT ID: NCT04588922

This clinical trial is studying a new medication called SLS009, which is designed to treat patients with certain blood cancers, specifically types of leukemia and lymphoma. The main goals of this s...

Recruiting

Phase: PHASE1 Conditions: Hematologic Malignancies

Study of Oral Atogepant Tablets to Assess Safety and Efficacy in Adult Participants With Migraine

NCT ID: NCT06241313

This clinical trial is studying a medication called atogepant, which is taken as a tablet, to see how well it works and how safe it is for adults who experience migraine attacks. Migraines are seve...

Recruiting

Phase: PHASE3 Conditions: Migraine

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Clinical Trials in Bengbu, Anhui

102 Active Trials Found in Bengbu

Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7

A Study of Bomedemstat (IMG-7289/MK-3543) Compared to Best Available Therapy (BAT) in Participants With Essential Thrombocythemia and an Inadequate Response or Intolerance of Hydroxyurea (MK-3543-006)

A Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011)

Randomized Study in Children and Adolescents With Migraine: Acute Treatment

Program to Assess Adverse Events and Change in Disease Activity of Oral Upadacitinib in Adult Participants With Moderate to Severe Systemic Lupus Erythematosus

A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)

Long-Term Safety Study of Deucravacitinib Versus Ustekinumab in Participants With Psoriasis (PRAGMATYK)

Clinical Trial of TQB2102 for Injection Versus Trastuzumab Emtansine for Injection in HER2-positive Advanced Breast Cancer

A Study to Assess Effectiveness and Safety of Deucravacitinib Compared With Placebo in Participants With Active Systemic Lupus Erythematosus (SLE)

A Study of Zasocitinib in Adults With Psoriatic Arthritis Who Have or Have Not Been Treated With Biologic Medicines

TQB2930 Injection for the Treatment of HER2-positive Advanced Breast Cancer

A Study of LUCAR-G79 in Subjects With Relapsed/Refractory Autoimmune Diseases

A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)

A Study of LUCAR-DKS1 in Subjects With Relapsed/Refractory Autoimmune Diseases

A Study of Imlunestrant Versus Standard Endocrine Therapy in Participants With Early Breast Cancer

Mirvetuximab Soravtansine With Bevacizumab Versus Bevacizumab as Maintenance in Platinum-sensitive Epithelial Ovarian, Fallopian Tube, or Peritoneal Cancer

A Study of DB-1303/BNT323 vs Investigator's Choice Chemotherapy in HER2-Low, Hormone Receptor Positive Metastatic Breast Cancer (DYNASTY-Breast02)

A Study of Lebrikizumab (LY3650150) in Adult Participants With Chronic Rhinosinusitis and Nasal Polyps Treated With Intranasal Corticosteroids (CONTRAST-NP)

Study of SLS009 (Formerly GFH009) a Potent Highly Selective CDK9 Inhibitor in Patients With Hematologic Malignancies

Study of Oral Atogepant Tablets to Assess Safety and Efficacy in Adult Participants With Migraine