Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-Small Cell Lung Cancer, ALCHEMIST Trial

NCT ID: NCT04267848

The ALCHEMIST trial is a clinical study looking at whether adding a drug called pembrolizumab, which is a type of immunotherapy, to standard chemotherapy can improve treatment outcomes for patients...

Recruiting

Phase: PHASE3 Conditions: Stage IIIB Lung Cancer AJCC v8, Stage IIIA Lung Cancer AJCC v8 +4 more

Efficacy and Safety of Frexalimab (SAR441344) in the Treatment of Systemic Lupus Erythematosus

NCT ID: NCT05039840

This clinical trial is studying a new treatment called Frexalimab (SAR441344) for adults aged 18 to 70 who have an active condition known as Systemic Lupus Erythematosus (SLE). The trial will compa...

Recruiting

Phase: PHASE2 Conditions: Systemic Lupus Erythematosus

A Study to Test Whether BI 771716 Helps People With an Advanced Form of Age-related Macular Degeneration (AMD) Called Geographic Atrophy

NCT ID: NCT06722157

This clinical trial is investigating a new treatment called BI 771716 for people aged 50 and older who have an advanced eye condition known as geographic atrophy, which is a type of age-related mac...

Recruiting

Phase: PHASE2 Conditions: Geographic Atrophy, Macular Degeneration, Age-related

A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events

NCT ID: NCT06112418

The TRANSFORM trial is a research study designed to compare two different approaches to help prevent heart problems in people who are at higher risk but do not currently have any symptoms of heart ...

Recruiting

Phase: NA Conditions: Diabetes Mellitus, Type 2, Metabolic Syndrome +1 more

Randomised Clinical Trial to Investigate Efficacy and Safety of Benralizumab 30 mg SC as an add-on Therapy in Uncontrolled Eosinophilic Asthma Patients Treated With Medium-dose ICS-LABA Compared to Conventional Escalation to High-dose ICS-LABA Treatment

NCT ID: NCT06750289

This clinical trial is studying a medication called benralizumab to see how well it works and how safe it is for people with uncontrolled eosinophilic asthma. Eosinophilic asthma is a type of asthm...

Recruiting

Phase: PHASE3 Conditions: Eosinophilic Asthma

A Study of LY3541860 in Adult Participants With Moderately to Severely Active Rheumatoid Arthritis

NCT ID: NCT06859294

This clinical trial is studying a new medication called LY3541860 to see how it helps adults with moderately to severely active rheumatoid arthritis (RA) who have not responded well to at least one...

Recruiting

Phase: PHASE2 Conditions: Rheumatoid Arthritis

[18F]PI-2620 Phase 3 Histopathological Study

NCT ID: NCT05641688

This clinical trial, called the [18F]PI-2620 Phase 3 Histopathological Study, is looking at a new imaging method using a special PET scan to detect tau protein in the brains of people with Alzheime...

Recruiting

Phase: PHASE3 Conditions: Alzheimer Disease

A Study to Evaluate Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderately to Severely Active Ulcerative Colitis (MK-7240-001)

NCT ID: NCT06052059

This clinical trial is studying a new medication called tulisokibart (MK-7240) to see if it is effective and safe for people with moderately to severely active ulcerative colitis, a condition that ...

Recruiting

Phase: PHASE3 Conditions: Ulcerative Colitis

A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)

NCT ID: NCT06430801

This clinical trial is studying a new medication called tulisokibart, which is being tested for its effectiveness and safety in treating people with moderate to severe Crohn's disease. Crohn's dise...

Recruiting

Phase: PHASE3 Conditions: Crohn's Disease

A Study to Evaluate the Efficacy and Safety of Bimekizumab in Adult Study Participants With Active Psoriatic Arthritis

NCT ID: NCT06624228

This clinical trial is studying the effectiveness and safety of a medication called bimekizumab for adults with active psoriatic arthritis (PsA). PsA is a type of arthritis that can cause joint pai...

Recruiting

Phase: PHASE3 Conditions: Psoriatic Arthritis

A U.S. Registry of Eosinophilic Esophagitis Adolescent and Adult Patients Treated With DUPIXENT® As Standard of Care

NCT ID: NCT06693531

This clinical trial is looking at how well a medication called DUPIXENT® (dupilumab) works for people with eosinophilic esophagitis (EoE), a condition that affects the esophagus and can make swallo...

Recruiting

Conditions: Eosinophilic Esophagitis (EoE)

A Study to Investigate Effectiveness of Tirzepatide Following Initiation of Ixekizumab in Participants With Active Psoriatic Arthritis and Overweight or Obesity in Clinical Practice (TOGETHER AMPLIFY-PsA)

NCT ID: NCT06864026

The TOGETHER AMPLIFY-PsA clinical trial is studying how effective the medication tirzepatide is when added to ixekizumab treatment for people with active psoriatic arthritis (PsA) who are also over...

Recruiting

Phase: PHASE4 Conditions: Psoriatic Arthritis, Overweight or Obesity

A Study to Investigate Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD), and Immunogenicity of RO7669330 in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)

NCT ID: NCT06961370

This clinical trial is studying a new treatment called RO7669330 for people with geographic atrophy (GA), a condition that can occur due to age-related macular degeneration (AMD), which affects vis...

Recruiting

Phase: PHASE1 Conditions: Age-related Macular Degeneration, Geographic Atrophy

ALTUS: Performance of a Multi- Target Hepatocellular Carcinoma (HCC) Test in Subjects With Increased Risk

NCT ID: NCT05064553

The ALTUS clinical trial is studying a new test called Oncoguard™ Liver, which aims to detect hepatocellular carcinoma (HCC), a type of liver cancer, in people who are at higher risk. This trial is...

Recruiting

Conditions: Hepatocellular Carcinoma, Hepatitis B +3 more

A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

NCT ID: NCT06819878

This clinical trial is studying a new treatment called RO7790121 for people with moderately to severely active Crohn's disease, a condition that causes inflammation in the digestive tract. The tria...

Recruiting

Phase: PHASE3 Conditions: Moderately to Severely Active Crohns Disease

A Study of the Efficacy and Safety of Efgartigimod in Patients With Primary Sjögren's Syndrome

NCT ID: NCT06684847

This clinical trial is studying a new treatment called efgartigimod for people with moderate-to-severe Primary Sjögren's Syndrome, which is an autoimmune condition that affects the glands that prod...

Recruiting

Phase: PHASE3 Conditions: Primary Sjogrens Disease

A Phase 2 Study of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease

NCT ID: NCT06680830

This clinical trial is studying a new treatment called NEU-411 for people aged 50 to 80 who have early Parkinson's Disease (PD) and have a specific genetic profile that suggests their symptoms may ...

Recruiting

Phase: PHASE2 Conditions: Parkinson Disease, Parkinson +3 more

A Study to Evaluate the Efficacy, Safety, and Tolerability of IMVT-1402 in Adult Participants With Active, Difficult to Treat Rheumatoid Arthritis

NCT ID: NCT06754462

This clinical trial is looking at a new treatment called IMVT-1402 for adults with rheumatoid arthritis (RA) that is difficult to manage. Rheumatoid arthritis is a condition where the immune system...

Recruiting

Phase: PHASE2 Conditions: Rheumatoid Arthritis

ReNEW:Phase 3 Study of Efficacy, Safety & Pharmacokinetics of Subcutaneous Injections of Elamipretide in Subjects With Dry Age-Related Macular Degeneration (Dry AMD)

NCT ID: NCT06373731

The ReNEW clinical trial is studying a new treatment called elamipretide for people with dry age-related macular degeneration (AMD), a condition that can lead to vision loss. The main goal is to se...

Recruiting

Phase: PHASE3 Conditions: Age Related Macular Degeneration (ARMD)

A Trial to Evaluate the Safety and Efficacy of Benfotiamine in Patients With Early Alzheimer's Disease (BenfoTeam)

NCT ID: NCT06223360

The BenfoTeam trial is studying a medication called Benfotiamine to see if it can help slow down the symptoms of early Alzheimer's disease. This study is specifically looking at people aged 50 to 8...

Recruiting

Phase: PHASE2 Conditions: Alzheimer Disease

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Clinical Trials in Sun City, Arizona

49 Active Trials Found in Sun City

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-Small Cell Lung Cancer, ALCHEMIST Trial

Efficacy and Safety of Frexalimab (SAR441344) in the Treatment of Systemic Lupus Erythematosus

A Study to Test Whether BI 771716 Helps People With an Advanced Form of Age-related Macular Degeneration (AMD) Called Geographic Atrophy

A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events

Randomised Clinical Trial to Investigate Efficacy and Safety of Benralizumab 30 mg SC as an add-on Therapy in Uncontrolled Eosinophilic Asthma Patients Treated With Medium-dose ICS-LABA Compared to Conventional Escalation to High-dose ICS-LABA Treatment

A Study of LY3541860 in Adult Participants With Moderately to Severely Active Rheumatoid Arthritis

[18F]PI-2620 Phase 3 Histopathological Study

A Study to Evaluate Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderately to Severely Active Ulcerative Colitis (MK-7240-001)

A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)

A Study to Evaluate the Efficacy and Safety of Bimekizumab in Adult Study Participants With Active Psoriatic Arthritis

A U.S. Registry of Eosinophilic Esophagitis Adolescent and Adult Patients Treated With DUPIXENT® As Standard of Care

A Study to Investigate Effectiveness of Tirzepatide Following Initiation of Ixekizumab in Participants With Active Psoriatic Arthritis and Overweight or Obesity in Clinical Practice (TOGETHER AMPLIFY-PsA)

A Study to Investigate Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD), and Immunogenicity of RO7669330 in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)

ALTUS: Performance of a Multi- Target Hepatocellular Carcinoma (HCC) Test in Subjects With Increased Risk

A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

A Study of the Efficacy and Safety of Efgartigimod in Patients With Primary Sjögren's Syndrome

A Phase 2 Study of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease

A Study to Evaluate the Efficacy, Safety, and Tolerability of IMVT-1402 in Adult Participants With Active, Difficult to Treat Rheumatoid Arthritis

ReNEW:Phase 3 Study of Efficacy, Safety & Pharmacokinetics of Subcutaneous Injections of Elamipretide in Subjects With Dry Age-Related Macular Degeneration (Dry AMD)

A Trial to Evaluate the Safety and Efficacy of Benfotiamine in Patients With Early Alzheimer's Disease (BenfoTeam)