Clinical Trials in Sun City, Arizona

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-Small Cell Lung Cancer, ALCHEMIST Trial

NCT ID: NCT04267848

The ALCHEMIST trial is a clinical study looking at whether adding a drug called pembrolizumab, which is a type of immunotherapy, to standard chemotherapy can improve treatment outcomes for patients...

A Study to Evaluate the Efficacy, Safety, and Tolerability of IMVT-1402 in Adult Participants With Active, Difficult to Treat Rheumatoid Arthritis

NCT ID: NCT06754462

This clinical trial is looking at a new treatment called IMVT-1402 for adults with rheumatoid arthritis (RA) that is difficult to manage. Rheumatoid arthritis is a condition where the immune system...

A Study to Evaluate Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderately to Severely Active Ulcerative Colitis (MK-7240-001)

NCT ID: NCT06052059

This clinical trial is studying a new medication called tulisokibart (MK-7240) to see if it is effective and safe for people with moderately to severely active ulcerative colitis, a condition that ...

Long-term Safety and Efficacy Extension Trial of Bimatoprost SR

NCT ID: NCT03891446

A U.S. Registry of Eosinophilic Esophagitis Adolescent and Adult Patients Treated With DUPIXENT® As Standard of Care

NCT ID: NCT06693531

This clinical trial is looking at how well a medication called DUPIXENT® (dupilumab) works for people with eosinophilic esophagitis (EoE), a condition that affects the esophagus and can make swallo...

A Trial to Evaluate the Safety and Efficacy of Benfotiamine in Patients With Early Alzheimer's Disease (BenfoTeam)

NCT ID: NCT06223360

The BenfoTeam trial is studying a medication called Benfotiamine to see if it can help slow down the symptoms of early Alzheimer's disease. This study is specifically looking at people aged 50 to 8...

A Study of Guselkumab Administered Subcutaneously in Bio-naive Participants With Active Psoriatic Arthritis Axial Disease

NCT ID: NCT04929210

This clinical trial is studying a medication called guselkumab to see how well it works for people with active psoriatic arthritis (PsA) that affects the spine and pelvis. The goal is to find out i...

A Study to Evaluate the Efficacy and Safety of Bimekizumab in Adult Study Participants With Active Psoriatic Arthritis

NCT ID: NCT06624228

This clinical trial is studying the effectiveness and safety of a medication called bimekizumab for adults with active psoriatic arthritis (PsA). PsA is a type of arthritis that can cause joint pai...

A Phase 2 Study of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease

NCT ID: NCT06680830

This clinical trial is studying a new treatment called NEU-411 for people aged 50 to 80 who have early Parkinson's Disease (PD) and have a specific genetic profile that suggests their symptoms may ...

A Study to Investigate Effectiveness of Tirzepatide Following Initiation of Ixekizumab in Participants With Active Psoriatic Arthritis and Overweight or Obesity in Clinical Practice (TOGETHER AMPLIFY-PsA)

NCT ID: NCT06864026

The TOGETHER AMPLIFY-PsA clinical trial is studying how effective the medication tirzepatide is when added to ixekizumab treatment for people with active psoriatic arthritis (PsA) who are also over...

A Study to Investigate Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD), and Immunogenicity of RO7669330 in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)

NCT ID: NCT06961370

This clinical trial is studying a new treatment called RO7669330 for people with geographic atrophy (GA), a condition that can occur due to age-related macular degeneration (AMD), which affects vis...

A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)

NCT ID: NCT06430801

This clinical trial is studying a new medication called tulisokibart, which is being tested for its effectiveness and safety in treating people with moderate to severe Crohn's disease. Crohn's dise...

PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort

NCT ID: NCT04477785

The Parkinson Progression Marker Initiative (PPMI) is a long-term study designed to better understand how Parkinson's disease (PD) progresses over time. The goal is to find specific markers—like cl...

A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events

NCT ID: NCT06112418

The TRANSFORM trial is a research study designed to compare two different approaches to help prevent heart problems in people who are at higher risk but do not currently have any symptoms of heart ...

A Study to Assess Adverse Events and Change in Disease Activity of Risankizumab Subcutaneous Induction Treatment for Moderately to Severely Active Crohn's Disease.

NCT ID: NCT06063967

This clinical trial is studying the safety and effectiveness of a medication called risankizumab for adults with moderately to severely active Crohn's disease, a long-term condition that causes ser...

A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

NCT ID: NCT06819878

This clinical trial is studying a new treatment called RO7790121 for people with moderately to severely active Crohn's disease, a condition that causes inflammation in the digestive tract. The tria...

Longitudinal Early-onset Alzheimer's Disease Study Protocol

NCT ID: NCT03507257

The Longitudinal Early-onset Alzheimer's Disease Study (LEADS) is a research study that aims to understand how early onset Alzheimer's disease and related conditions progress over time. The study i...

A Study of Vedolizumab Intravenous (IV) and Adalimumab or Vedolizumab and Ustekinumab in Adults With Crohn's Disease

NCT ID: NCT06045754

This clinical trial is investigating the effects of a treatment called vedolizumab, given through an IV, combined with two other medications, adalimumab or ustekinumab, in adults with moderate to s...

AGN-193408 SR in the Treatment of Open-angle Glaucoma or Ocular Hypertension

NCT ID: NCT04499248

The clinical trial titled "AGN-193408 SR in the Treatment of Open-angle Glaucoma or Ocular Hypertension" is studying a new treatment for individuals with open-angle glaucoma (a common eye condition...

A Study to Test Whether BI 771716 Helps People With an Advanced Form of Age-related Macular Degeneration (AMD) Called Geographic Atrophy

NCT ID: NCT06722157

This clinical trial is investigating a new treatment called BI 771716 for people aged 50 and older who have an advanced eye condition known as geographic atrophy, which is a type of age-related mac...