A 2-stage, Phase III Study to Investigate the Efficacy and Safety of Anifrolumab in Adults With Chronic and/or Subacute Cutaneous Lupus Erythematosus

NCT ID: NCT06015737

This clinical trial is studying a medication called anifrolumab to see if it helps adults with a skin condition known as cutaneous lupus erythematosus (CLE). The trial will compare the effects of a...

Recruiting

Phase: PHASE3 Conditions: Cutaneous Lupus Erythematosus

A Study to Evaluate the Efficacy and Safety of Dazodalibep in Participants With Sjögren's Syndrome (SS) With Moderate-to-severe Systemic Disease Activity

NCT ID: NCT06104124

This clinical trial is studying a new medication called dazodalibep to see how well it works for people with Sjögren's syndrome (SS), especially those who have moderate to severe symptoms affecting...

Recruiting

Phase: PHASE3 Conditions: Sjogren's Syndrome

A Study of Imlunestrant Versus Standard Endocrine Therapy in Participants With Early Breast Cancer

NCT ID: NCT05514054

This clinical trial is studying a new treatment called imlunestrant to see how well it works compared to standard hormone therapy for patients with early breast cancer. The patients being considere...

Recruiting

Phase: PHASE3 Conditions: Breast Neoplasms

Program to Assess Adverse Events and Change in Disease Activity of Oral Upadacitinib in Adult Participants With Moderate to Severe Systemic Lupus Erythematosus

NCT ID: NCT05843643

This clinical trial is studying the safety and effectiveness of a medication called upadacitinib for adults with moderate to severe systemic lupus erythematosus (SLE), a disease that causes inflamm...

Recruiting

Phase: PHASE3 Conditions: Systemic Lupus Erythematosus

A Master Protocol Study (LY900028) of Multiple Intervention-Specific-Appendices (ISAs) in Participants With Chronic Pain

NCT ID: NCT05986292

This clinical trial is designed to study different treatments for chronic pain, specifically in people suffering from conditions like osteoarthritis, knee pain, diabetic neuropathic pain, and chron...

Recruiting

Phase: PHASE2 Conditions: Osteoarthritis, Knee, Chronic Low-back Pain +1 more

A Study to Investigate the Effect of Lepodisiran on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) - ACCLAIM-Lp(a)

NCT ID: NCT06292013

The ACCLAIM-Lp(a) trial is studying a new treatment called lepodisiran to see if it can help reduce the risk of serious heart problems in adults who have high levels of a substance called lipoprote...

Recruiting

Phase: PHASE3 Conditions: Elevated Lp(a), Atherosclerotic Cardiovascular Disease (ASCVD)

The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Kidney Outcomes in Adults Living With Obesity (TRIUMPH-Outcomes)

NCT ID: NCT06383390

The TRIUMPH-OUTCOMES study is looking at a new treatment called retatrutide, which is given once a week, to see if it can help reduce serious heart problems and protect kidney function in adults wh...

Recruiting

Phase: PHASE3 Conditions: Chronic Kidney Disease (CKD), Atherosclerotic Cardiovascular Disease (ASCVD)

A Study of Nipocalimab in Adult Participants With Active Lupus Nephritis

NCT ID: NCT04883619

This clinical trial is investigating a new treatment called nipocalimab for adults who have active Lupus Nephritis, a condition where the immune system causes inflammation in the kidneys. The main ...

Not yet recruiting

Phase: PHASE2 Conditions: Lupus Nephritis

A Study to Evaluate the Efficacy and Safety of Icotrokinra (JNJ-77242113) in Biologic-experienced Participants With Active Psoriatic Arthritis

NCT ID: NCT06807424

This clinical trial is studying a new medication called icotrokinra to see how well it works and how safe it is for people with active psoriatic arthritis (PsA) who have already tried other biologi...

Recruiting

Phase: PHASE3 Conditions: Arthritis, Psoriatic

A Study to Assess Adverse Events and Effectiveness of Gel Stent (XEN63) Implantation Using Ab Interno and Ab Externo Approaches in Adult Participants With Glaucoma

NCT ID: NCT06822738

This clinical trial is studying a new treatment option for adults with primary open-angle glaucoma, a condition that can lead to vision loss if not properly managed. The trial is specifically looki...

Recruiting

Phase: PHASE3 Conditions: Primary Open Angle Glaucoma

A Safety and Efficacy Study of Dazodalibep in Participants With Sjögren's Syndrome (SS) With Moderate-to-Severe Symptom State

NCT ID: NCT06245408

This clinical trial is studying a new treatment called dazodalibep for patients with Sjögren's Syndrome (SS), specifically those who experience moderate to severe symptoms. The main goal is to see ...

Recruiting

Phase: PHASE3 Conditions: Sjögren's Syndrome (SS)

A Study to Evaluate the Safety and Efficacy of Ruxolitinib Cream in Pediatric Participants With Nonsegmental Vitiligo

NCT ID: NCT06548360

This clinical trial is studying a new cream called ruxolitinib to see if it is safe and effective for children with nonsegmental vitiligo, a condition where patches of skin lose their color. The tr...

Recruiting

Phase: PHASE3 Conditions: NonSegmental Vitiligo

A Study to Evaluate the Efficacy and Safety of Bimekizumab in Adult Study Participants With Active Psoriatic Arthritis

NCT ID: NCT06624228

This clinical trial is studying the effectiveness and safety of a medication called bimekizumab for adults with active psoriatic arthritis (PsA). PsA is a type of arthritis that can cause joint pai...

Recruiting

Phase: PHASE3 Conditions: Psoriatic Arthritis

A Study to Assess the Long-term Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-3)

NCT ID: NCT06929273

The BALSAM-3 clinical trial is studying the long-term safety of a medication called KarXT for people with Bipolar-I Disorder who are experiencing manic episodes. This is an important study because ...

Not yet recruiting

Phase: PHASE3 Conditions: Bipolar Disorder Type I With Mania

Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis

NCT ID: NCT05485961

This clinical trial is studying a medication called CSL300 (Clazakizumab) to see if it can help improve heart health for adults with end-stage kidney disease (ESKD) who are undergoing dialysis. The...

Recruiting

Phase: PHASE2 Conditions: Atherosclerotic Cardiovascular Disease, End Stage Kidney Disease +1 more

A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer.

NCT ID: NCT06629779

This clinical trial is studying a new drug called PF-06821497 (also known as Mevrometostat) to see if it works better when combined with another medication called enzalutamide for men with metastat...

Recruiting

Phase: PHASE3 Conditions: Metastatic Castration-Resistant Prostate Cancer

A Study to Investigate Effectiveness of Tirzepatide Following Initiation of Ixekizumab in Participants With Active Psoriatic Arthritis and Overweight or Obesity in Clinical Practice (TOGETHER AMPLIFY-PsA)

NCT ID: NCT06864026

The TOGETHER AMPLIFY-PsA clinical trial is studying how effective the medication tirzepatide is when added to ixekizumab treatment for people with active psoriatic arthritis (PsA) who are also over...

Recruiting

Phase: PHASE4 Conditions: Psoriatic Arthritis, Overweight or Obesity

Enlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) Cardiovascular Outcomes Study (MK-0616-015) CORALreef Outcomes

NCT ID: NCT06008756

The CORALreef study is a clinical trial that is looking at a new medication called enlicitide decanoate, which is an oral treatment designed to help lower cholesterol and reduce the risk of serious...

Recruiting

Phase: PHASE3 Conditions: Arteriosclerosis, Hypercholesterolaemia

A Phase 2 Study to Investigate Efficacy and Safety of HZN-1116 in Participants With Sjogren's Syndrome

NCT ID: NCT06312020

This clinical trial is investigating a new treatment called HZN-1116 for people with Sjogren's syndrome, a condition that affects moisture-producing glands and can cause dry mouth and eyes, among o...

Recruiting

Phase: PHASE2 Conditions: Sjogren's Syndrome

Study of PF-07220060 With Letrozole in Adults With HR-positive HER2-negative Breast Cancer Who Have Not Received Anticancer Treatment for Advanced/Metastatic Disease

NCT ID: NCT06760637

This clinical trial is studying a new treatment called PF-07220060, given alongside letrozole, for adults with a specific type of breast cancer known as HR-positive HER2-negative breast cancer. Thi...

Recruiting

Phase: PHASE3 Conditions: Breast Cancer

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Clinical Trials in Glendale, Arizona

51 Active Trials Found in Glendale

A 2-stage, Phase III Study to Investigate the Efficacy and Safety of Anifrolumab in Adults With Chronic and/or Subacute Cutaneous Lupus Erythematosus

A Study to Evaluate the Efficacy and Safety of Dazodalibep in Participants With Sjögren's Syndrome (SS) With Moderate-to-severe Systemic Disease Activity

A Study of Imlunestrant Versus Standard Endocrine Therapy in Participants With Early Breast Cancer

Program to Assess Adverse Events and Change in Disease Activity of Oral Upadacitinib in Adult Participants With Moderate to Severe Systemic Lupus Erythematosus

A Master Protocol Study (LY900028) of Multiple Intervention-Specific-Appendices (ISAs) in Participants With Chronic Pain

A Study to Investigate the Effect of Lepodisiran on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) - ACCLAIM-Lp(a)

The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Kidney Outcomes in Adults Living With Obesity (TRIUMPH-Outcomes)

A Study of Nipocalimab in Adult Participants With Active Lupus Nephritis

A Study to Evaluate the Efficacy and Safety of Icotrokinra (JNJ-77242113) in Biologic-experienced Participants With Active Psoriatic Arthritis

A Study to Assess Adverse Events and Effectiveness of Gel Stent (XEN63) Implantation Using Ab Interno and Ab Externo Approaches in Adult Participants With Glaucoma

A Safety and Efficacy Study of Dazodalibep in Participants With Sjögren's Syndrome (SS) With Moderate-to-Severe Symptom State

A Study to Evaluate the Safety and Efficacy of Ruxolitinib Cream in Pediatric Participants With Nonsegmental Vitiligo

A Study to Evaluate the Efficacy and Safety of Bimekizumab in Adult Study Participants With Active Psoriatic Arthritis

A Study to Assess the Long-term Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-3)

Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis

A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer.

A Study to Investigate Effectiveness of Tirzepatide Following Initiation of Ixekizumab in Participants With Active Psoriatic Arthritis and Overweight or Obesity in Clinical Practice (TOGETHER AMPLIFY-PsA)

Enlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) Cardiovascular Outcomes Study (MK-0616-015) CORALreef Outcomes

A Phase 2 Study to Investigate Efficacy and Safety of HZN-1116 in Participants With Sjogren's Syndrome

Study of PF-07220060 With Letrozole in Adults With HR-positive HER2-negative Breast Cancer Who Have Not Received Anticancer Treatment for Advanced/Metastatic Disease