Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

NCT ID: NCT04267848

The ALCHEMIST trial is a clinical study looking at whether adding a drug called pembrolizumab, which is a type of immunotherapy, to standard chemotherapy can improve treatment outcomes for patients...

Recruiting

Phase: PHASE3 Conditions: Stage IIIB Lung Cancer AJCC v8, Stage IIIA Lung Cancer AJCC v8 +4 more

Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study

NCT ID: NCT04269902

**Summary of the EVOLVE CLL/SLL Study** The EVOLVE CLL/SLL study is a clinical trial designed to find out if starting treatment for high-risk chronic lymphocytic leukemia (CLL) or small lymphocyti...

Recruiting

Phase: PHASE3 Conditions: Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma

Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial)

NCT ID: NCT05554393

This clinical trial, called the MyeloMATCH Treatment Trial, is studying different treatment combinations for younger patients with a type of blood cancer known as acute myeloid leukemia (AML). The ...

Recruiting

Phase: PHASE2 Conditions: Acute Myeloid Leukemia

Testing the Effects of Novel Therapeutics for Newly Diagnosed, Untreated Patients With High-Risk Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)

NCT ID: NCT05554406

This clinical trial, called the MyeloMATCH Treatment Trial, is investigating different treatment options for adults who have recently been diagnosed with a serious form of blood cancer called high-...

Recruiting

Phase: PHASE2 Conditions: Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm +2 more

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

NCT ID: NCT05564390

The MYELOMATCH trial is a research study designed to help people with certain types of blood cancers, specifically acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). The main goal of ...

Recruiting

Phase: PHASE2 Conditions: Acute Myeloid Leukemia, Myelodysplastic Syndrome

Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study

NCT ID: NCT05987241

The MODERN study is a clinical trial designed to explore how a blood test can help identify bladder cancer patients who may need additional treatment after having their bladder surgically removed. ...

Recruiting

Phase: PHASE2 Conditions: Stage III Bladder Urothelial Carcinoma AJCC v6 and v7, Stage IV Bladder Urothelial Carcinoma AJCC v7 +5 more

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

NCT ID: NCT06172296

This clinical trial is studying a new treatment approach for children with high-risk neuroblastoma, a type of cancer that affects nerve cells. The researchers want to find out if combining a medici...

Recruiting

Phase: PHASE3 Conditions: Neuroblastoma, Ganglioneuroblastoma, Nodular

Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas

NCT ID: NCT06422806

This clinical trial is studying whether adding a type of treatment called immunotherapy (specifically pembrolizumab) to standard chemotherapy (doxorubicin) can help patients with aggressive types o...

Recruiting

Phase: PHASE3 Conditions: Stage III Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8, Metastatic Undifferentiated Pleomorphic Sarcoma +4 more

LIVERAGE™: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver Fibrosis

NCT ID: NCT06632444

The LIVERAGE™ clinical trial is studying a medication called survodutide to see if it can help adults with a liver disease known as Metabolic Dysfunction Associated Steatohepatitis (MASH) who also ...

Recruiting

Phase: PHASE3 Conditions: Liver Fibrosis, Metabolic Dysfunction Associated Steatohepatitis (MASH)

LIVERAGE™ - Cirrhosis: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Cirrhosis

NCT ID: NCT06632457

The LIVERAGE™ study is researching whether a medication called survodutide can help adults with a liver disease known as non-alcoholic steatohepatitis (NASH) or metabolic-associated steatohepatitis...

Recruiting

Phase: PHASE3 Conditions: Metabolic Dysfunction Associated Steatohepatitis

A Randomized, Double-Blind, Placebo-Controlled Trial on Efficacy and Safety of Fluticasone Propionate/Albuterol Sulfate Combination in Participants 12 Years and Older With Asthma

NCT ID: NCT06664619

This clinical trial is testing a new inhaler that combines two medications, fluticasone propionate and albuterol sulfate, to see how well it works and how safe it is for people aged 12 and older wi...

Recruiting

Phase: PHASE3 Conditions: Asthma

Investigating an mRNA CAR T-cell Therapy, Known as Descartes-08, as a Potential Approach to Treat Myasthenia Gravis

NCT ID: NCT06799247

The AURORA Study is a clinical trial that is exploring a new treatment called Descartes-08, which uses mRNA CAR T-cell therapy, for adults with a condition known as generalized myasthenia gravis (g...

Recruiting

Phase: PHASE3 Conditions: Myasthaenia Gravis

Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

NCT ID: NCT07037459

This clinical trial is studying a medicine called maridebart cafraglutide to see if it can help people who have heart failure with either preserved or mildly reduced heart function, and who are als...

Recruiting

Phase: PHASE3 Conditions: Obesity, Heart Failure With Preserved Ejection Fraction +1 more

Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancer

NCT ID: NCT01810913

This clinical trial is exploring new treatment options for patients with high-risk head and neck cancers, specifically those that begin in the thin, flat cells called squamous cells. The researcher...

Recruiting

Phase: PHASE2 Conditions: Stage III Oropharyngeal Squamous Cell Carcinoma AJCC v7, Stage IV Hypopharyngeal Squamous Cell Carcinoma AJCC v7 +7 more

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

NCT ID: NCT03866382

This clinical trial is investigating how well three medications—cabozantinib, nivolumab, and ipilimumab—work together to treat patients with rare genitourinary tumors that have spread to other part...

Recruiting

Phase: PHASE2 Conditions: Stage IVB Prostate Cancer AJCC v8, Stage IV Renal Cell Cancer AJCC v8 +43 more

Pan Tumor Rollover Study

NCT ID: NCT03899155

The Pan Tumor Rollover Study is a clinical trial focused on understanding the long-term safety of a cancer treatment called nivolumab, both on its own and in combination with other therapies. This ...

Recruiting

Phase: PHASE2 Conditions: Cancer

Testing the Addition of Radiation Therapy to the Usual Immune Therapy Treatment (Atezolizumab) for Extensive Stage Small Cell Lung Cancer, The RAPTOR Trial

NCT ID: NCT04402788

The RAPTOR Trial is a clinical study looking at whether adding radiation therapy to the usual treatment with atezolizumab can help patients with extensive stage small cell lung cancer. This type of...

Recruiting

Phase: PHASE2 Conditions: Extensive Stage Lung Small Cell Carcinoma

LEGEND Study: EG-70 in NMIBC Patients BCG-Unresponsive and High-Risk NMIBC Incompletely Treated With BCG or BCG-Naïve

NCT ID: NCT04752722

The LEGEND Study is a clinical trial that is investigating a new treatment called EG-70 for patients with a type of bladder cancer known as non-muscle invasive bladder cancer (NMIBC). Specifically,...

Recruiting

Phase: PHASE1 Conditions: Superficial Bladder Cancer, Non-muscle Invasive Bladder Cancer With Carcinoma in Situ

Testing the Combination of Venetoclax and Rituximab, in Comparison to the Usual Treatment (Ibrutinib and Rituximab) for Waldenstrom's Macroglobulinemia/Lymphoplasmacytic Lymphoma

NCT ID: NCT04840602

This clinical trial is testing a new treatment for patients with Waldenstrom's macroglobulinemia, a type of blood cancer. Researchers want to see if combining two medications, venetoclax and rituxi...

Recruiting

Phase: PHASE2 Conditions: Waldenstrom Macroglobulinemia, Lymphoplasmacytic Lymphoma

Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma

NCT ID: NCT05256225

This clinical trial is studying the effects of adding two targeted therapies, trastuzumab (also known as Herceptin) and pertuzumab, to standard chemotherapy for women with certain types of uterine ...

Recruiting

Phase: PHASE3 Conditions: Endometrial Carcinoma, Endometrial Serous Adenocarcinoma +6 more

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Clinical Trials in Tucson, Arizona

579 Active Trials Found in Tucson

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study

Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial)

Testing the Effects of Novel Therapeutics for Newly Diagnosed, Untreated Patients With High-Risk Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas

LIVERAGE™: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver Fibrosis

LIVERAGE™ - Cirrhosis: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Cirrhosis

A Randomized, Double-Blind, Placebo-Controlled Trial on Efficacy and Safety of Fluticasone Propionate/Albuterol Sulfate Combination in Participants 12 Years and Older With Asthma

Investigating an mRNA CAR T-cell Therapy, Known as Descartes-08, as a Potential Approach to Treat Myasthenia Gravis

Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancer

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

Pan Tumor Rollover Study

Testing the Addition of Radiation Therapy to the Usual Immune Therapy Treatment (Atezolizumab) for Extensive Stage Small Cell Lung Cancer, The RAPTOR Trial

LEGEND Study: EG-70 in NMIBC Patients BCG-Unresponsive and High-Risk NMIBC Incompletely Treated With BCG or BCG-Naïve

Testing the Combination of Venetoclax and Rituximab, in Comparison to the Usual Treatment (Ibrutinib and Rituximab) for Waldenstrom's Macroglobulinemia/Lymphoplasmacytic Lymphoma

Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma