Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)

NCT ID: NCT03486873

This clinical trial, called MK-3475-587, is looking into the long-term safety and effectiveness of a treatment called pembrolizumab (also known as MK-3475) for patients with advanced tumors. If you...

Recruiting

Phase: PHASE3 Conditions: Solid Tumors, Hematologic Malignancies

A Trial to Learn How Well Linvoseltamab Works Compared to the Combination of Elotuzumab, Pomalidomide and Dexamethasone for Adult Participants With Relapsed/Refractory Multiple Myeloma

NCT ID: NCT05730036

This clinical trial is studying a new drug called linvoseltamab to see how well it works for adults with relapsed or refractory multiple myeloma—a type of blood cancer that has come back after trea...

Recruiting

Phase: PHASE3 Conditions: Relapsed Refractory Multiple Myeloma (RRMM)

Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation

NCT ID: NCT06252649

This clinical trial is studying a new treatment approach for patients with metastatic colorectal cancer that has a specific genetic change known as the KRAS p.G12C mutation. Researchers want to see...

Recruiting

Phase: PHASE3 Conditions: Metastatic Colorectal Cancer

Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015)

NCT ID: NCT04924075

This clinical trial is studying a new treatment called belzutifan for patients with certain advanced tumors, including pheochromocytoma, paraganglioma, pancreatic neuroendocrine tumors, and other s...

Recruiting

Phase: PHASE2 Conditions: Pancreatic Neuroendocrine Tumor, Von Hippel-Lindau Disease +3 more

Randomized Interval Assessment Trial of Lu177-Dotatate in Slowly Progressive G1-2 Advanced Midgut Neuroendocrine Tumors

NCT ID: NCT06878664

This clinical trial is studying a treatment called 177Lu-Dotatate for patients with slowly progressing advanced midgut neuroendocrine tumors (NETs), which are a type of cancer. The trial will invol...

Recruiting

Phase: PHASE3 Conditions: Grade1-2 Advanced Midgut Neuroendocrine Tumors (NETs)

Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study

NCT ID: NCT06937086

This clinical trial is investigating whether a combination of two medications, mirikizumab and tirzepatide, can help adults with ulcerative colitis (UC) and obesity or overweight to reduce their UC...

Recruiting

Phase: PHASE3 Conditions: Ulcerative Colitis, Obesity or Overweight

Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight

NCT ID: NCT06937099

This clinical trial is investigating the effectiveness and safety of a treatment combining two medications, mirikizumab and tirzepatide, for adults who have Crohn's disease that is moderately to se...

Recruiting

Phase: PHASE3 Conditions: Crohn's Disease, Obesity or Overweight

A Study to Learn About the Occurrence of Disseminated Intravascular Coagulation in People With Sepsis and Further Worsening of Sepsis

NCT ID: NCT06986798

This clinical trial is exploring how a serious condition called sepsis can lead to another dangerous issue known as disseminated intravascular coagulation (DIC). Sepsis occurs when the body has a s...

Recruiting

Phase: NA Conditions: Sepsis, Sepsis Associated DIC

A Study to Compare Iberdomide Maintenance Versus Lenalidomide Maintenance Therapy Following Autologous Stem Cell Transplant in Participants With Newly Diagnosed Multiple Myeloma

NCT ID: NCT05827016

This clinical trial is studying two different treatments for patients with newly diagnosed multiple myeloma, a type of blood cancer. Specifically, it compares iberdomide maintenance therapy to lena...

Recruiting

Phase: PHASE3 Conditions: Multiple Myeloma

A Study of the Efficacy and Safety of Adjuvant Autogene Cevumeran Plus Atezolizumab and mFOLFIRINOX Versus mFOLFIRINOX Alone in Participants With Resected PDAC

NCT ID: NCT05968326

This clinical trial is studying a new treatment approach for patients with resected pancreatic ductal adenocarcinoma (PDAC), which is a type of pancreatic cancer. The researchers want to see if add...

Recruiting

Phase: PHASE2 Conditions: Adenocarcinoma, Pancreatic Ductal

A Study to Learn if a Combination of Fianlimab and Cemiplimab Versus Cemiplimab Alone is More Effective for Adult Participants With Advanced Non-Small Cell Lung Cancer (NSCLC)

NCT ID: NCT05785767

This clinical trial is studying whether a new combination of two medications, fianlimab and cemiplimab, is more effective for treating advanced non-small cell lung cancer (NSCLC) than cemiplimab al...

Recruiting

Phase: PHASE2 Conditions: Advanced Non-Small Cell Lung Cancer

A Trial to Learn if Odronextamab is Safe and Well-Tolerated and How Well it Works Compared to Rituximab Combined With Different Types of Chemotherapy for Participants With Follicular Lymphoma

NCT ID: NCT06091254

This clinical trial is studying a new experimental drug called odronextamab to see if it is safe and effective for people with follicular lymphoma, a type of blood cancer. The trial has two parts: ...

Recruiting

Phase: PHASE3 Conditions: Follicular Lymphoma (FL)

A Trial to Learn if Odronextamab Combined With Lenalidomide is Safe and Works Better Than Rituximab Combined With Lenalidomide in Adult Participants With Follicular Lymphoma and Marginal Zone Lymphoma

NCT ID: NCT06149286

This clinical trial is studying a new treatment for adults with two specific types of cancer: follicular lymphoma and marginal zone lymphoma, especially for those whose cancer has returned after tr...

Recruiting

Phase: PHASE3 Conditions: Marginal Zone Lymphoma (MZL), Relapsed/Refractory Follicular Lymphoma

A Trial to Learn if the Combination of Fianlimab, Cemiplimab, and Chemotherapy is Safe and Works Better Than the Combination of Cemiplimab and Chemotherapy in Adult Patients With Non-Small Cell Lung Cancer That Can be Treated With Surgery

NCT ID: NCT06161441

This clinical trial is investigating a new treatment for adults with a specific type of lung cancer called resectable non-small cell lung cancer (NSCLC), which means the cancer can be removed by su...

Recruiting

Phase: PHASE2 Conditions: Resectable Non-small Cell Lung Cancer

A Clinical Study of MK-2870 Alone or With Other Treatments to Treat Gastrointestinal Cancers (MK-9999-02A)

NCT ID: NCT06428409

This clinical trial is investigating a new treatment called sacituzumab tirumotecan (MK-2870) to see how well it works alone or in combination with chemotherapy for certain advanced gastrointestina...

Recruiting

Phase: PHASE1 Conditions: Colorectal Cancer, Pancreatic Ductal Adenocarcinoma +1 more

A Study Evaluating the Efficacy and Safety of Pirtobrutinib in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

NCT ID: NCT06588478

This clinical trial is studying a new medication called Pirtobrutinib to see how well it works and how safe it is for people with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (S...

Recruiting

Phase: PHASE2 Conditions: Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma

Study of Patritumab Deruxtecan in Participants With Gastrointestinal Cancers (MK-1022-011) (HERTHENA-PanTumor02)

NCT ID: NCT06596694

This clinical trial is studying a new treatment called patritumab deruxtecan for people with advanced gastrointestinal (GI) cancers. Specifically, it focuses on cancers that have spread to other pa...

Recruiting

Phase: PHASE1 Conditions: Gastrointestinal Cancer

A Study to Evaluate the Long-Term Efficacy and Safety of Mirikizumab in Participants With Moderately to Severely Active Ulcerative Colitis (LUCENT 3)

NCT ID: NCT03519945

The LUCENT 3 clinical trial is studying a medication called mirikizumab to see how effective and safe it is for treating people with moderately to severely active ulcerative colitis (UC) over a lon...

Recruiting

Phase: PHASE3 Conditions: Ulcerative Colitis

FrexalimAB in Preservation of Endogenous insULIN Secretion Compared to Placebo in adUlts and Adolescents on Top of inSulin Therapy (FABULINUS)

NCT ID: NCT06111586

The FABULINUS trial is studying a new treatment called frexalimab for people with Type 1 Diabetes Mellitus (T1D) who are already using insulin. The goal of the trial is to see if frexalimab can hel...

Recruiting

Phase: PHASE2 Conditions: Type 1 Diabetes Mellitus

Study of Perioperative Dostarlimab in Participants With Untreated T4N0 or Stage III dMMR/MSI-H Resectable Colon Cancer

NCT ID: NCT05855200

This clinical trial is studying a medication called dostarlimab for patients with a specific type of colon cancer that has not been treated yet. The trial is focused on patients who have a form of ...

Recruiting

Phase: PHASE3 Conditions: Colonic Neoplasms, Neoplasms, Colon

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Clinical Trials in Oviedo, Asturias

83 Active Trials Found in Oviedo

Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)

A Trial to Learn How Well Linvoseltamab Works Compared to the Combination of Elotuzumab, Pomalidomide and Dexamethasone for Adult Participants With Relapsed/Refractory Multiple Myeloma

Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation

Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015)

Randomized Interval Assessment Trial of Lu177-Dotatate in Slowly Progressive G1-2 Advanced Midgut Neuroendocrine Tumors

Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study

Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight

A Study to Learn About the Occurrence of Disseminated Intravascular Coagulation in People With Sepsis and Further Worsening of Sepsis

A Study to Compare Iberdomide Maintenance Versus Lenalidomide Maintenance Therapy Following Autologous Stem Cell Transplant in Participants With Newly Diagnosed Multiple Myeloma

A Study of the Efficacy and Safety of Adjuvant Autogene Cevumeran Plus Atezolizumab and mFOLFIRINOX Versus mFOLFIRINOX Alone in Participants With Resected PDAC

A Study to Learn if a Combination of Fianlimab and Cemiplimab Versus Cemiplimab Alone is More Effective for Adult Participants With Advanced Non-Small Cell Lung Cancer (NSCLC)

A Trial to Learn if Odronextamab is Safe and Well-Tolerated and How Well it Works Compared to Rituximab Combined With Different Types of Chemotherapy for Participants With Follicular Lymphoma

A Trial to Learn if Odronextamab Combined With Lenalidomide is Safe and Works Better Than Rituximab Combined With Lenalidomide in Adult Participants With Follicular Lymphoma and Marginal Zone Lymphoma

A Trial to Learn if the Combination of Fianlimab, Cemiplimab, and Chemotherapy is Safe and Works Better Than the Combination of Cemiplimab and Chemotherapy in Adult Patients With Non-Small Cell Lung Cancer That Can be Treated With Surgery

A Clinical Study of MK-2870 Alone or With Other Treatments to Treat Gastrointestinal Cancers (MK-9999-02A)

A Study Evaluating the Efficacy and Safety of Pirtobrutinib in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Study of Patritumab Deruxtecan in Participants With Gastrointestinal Cancers (MK-1022-011) (HERTHENA-PanTumor02)

A Study to Evaluate the Long-Term Efficacy and Safety of Mirikizumab in Participants With Moderately to Severely Active Ulcerative Colitis (LUCENT 3)

FrexalimAB in Preservation of Endogenous insULIN Secretion Compared to Placebo in adUlts and Adolescents on Top of inSulin Therapy (FABULINUS)

Study of Perioperative Dostarlimab in Participants With Untreated T4N0 or Stage III dMMR/MSI-H Resectable Colon Cancer