Clinical Trials for Cognitive Decline

MIND Foods and Aerobic Training in Black Adults With HTN

NCT ID: NCT06152614

This clinical trial is studying how the MIND diet and aerobic exercise can help improve thinking and memory in Black adults with high blood pressure. The researchers are comparing two groups: one g...

Development of a Prediction Model for Delirium After Cardiac Surgery Using a Novel Self-Administered Preoperative Cognitive Assessment Tool

NCT ID: NCT03360838

This clinical trial is studying a tool called CogCheck, which is a self-administered assessment designed to predict the risk of delirium after heart surgery. Delirium is a condition that can cause ...

Polypill and RiscOMeter to Prevent StrOke and CogniTive ImpairmEnt (PROMOTE)

NCT ID: NCT05155137

The PROMOTE trial is studying whether a special combination pill, known as a polypill, can help prevent strokes and cognitive decline (which means problems with memory and thinking) in adults aged ...

Tau Pet Imaging in the Aging Brain Cohort Dedicated to Diversity Study

NCT ID: NCT05393388

The Tau PET Imaging study is looking to understand how changes in the brain relate to cognitive decline and early signs of Alzheimer’s disease in older adults. Researchers will use a special brain ...

Exercise Adherence and Cognitive Decline

NCT ID: NCT06769022

This clinical trial, titled "Exercise Adherence and Cognitive Decline," is investigating a new program designed to help people aged 45 to 65 from the Black community increase their physical activit...

A Multi-Modal Combination Intervention to Promote Cognitive Function in Older Intensive Care Unit Survivors

NCT ID: NCT06411561

This clinical trial is investigating a new approach to help older patients who have survived serious illnesses in the intensive care unit (ICU). Many of these patients, especially those aged 60 and...

40 Hz Transcranial Alternating Current Stimulation for Inducing Gamma Oscillations

NCT ID: NCT06740864

This clinical trial is exploring a treatment called 40 Hz transcranial alternating current stimulation (tACS) to see how it affects brain activity and working memory in healthy older adults. The st...

Effects of 3-Month Melatonin Treatment on Regional Cerebellar Structure and Blood Biomarkers in Alzheimer's Disease Spectrum

NCT ID: NCT06756828

This clinical trial is studying the effects of melatonin, a natural sleep aid, on patients with early signs of Alzheimer's disease, particularly those who also have trouble sleeping. Researchers wa...

Efficacy of a Multidomain Intervention on Lifestyle Risk Factors for Dementia Prevention

NCT ID: NCT06748625

This clinical trial, called the Luci program, is studying how lifestyle changes can help reduce the risk of dementia for middle-aged and older adults. Researchers believe that by improving habits l...

Preventing Cognitive Decline by Reducing BP Target Trial

NCT ID: NCT05106036

The Preventing Cognitive Decline by Reducing BP Target Trial (PCOT) is a study aimed at understanding how better management of high blood pressure (BP) can help older adults avoid problems with mem...

ViewMind Atlas Cognition

NCT ID: NCT06746844

Association of Transcranial Alternating Current Stimulation with Digital Cognitive Training for Cognitive Remediation in Older Adults

NCT ID: NCT06733714

This clinical trial is exploring a combination of two innovative approaches—Digital Cognitive Training (DCT) and Transcranial Alternating Current Stimulation (tACS)—to help improve cognitive functi...

Association Between Blood Pressure and Risk of PSCI

NCT ID: NCT06730711

This clinical trial is looking at how blood pressure affects thinking and memory problems after someone has a stroke. Researchers want to understand if there’s a connection between high or low bloo...

Measuring and Mapping Cognitive Decline After Brain Radiosurgery

NCT ID: NCT06466720

This clinical trial is studying how a specific type of treatment for brain tumors, called Stereotactic Radiosurgery (SRS), affects brain function over time. SRS is often used to treat patients with...

Effects of Blood Pressure on Cognition and Cerebral Hemodynamics in PD

NCT ID: NCT06252376

This clinical trial is studying how changes in blood pressure affect thinking abilities and blood flow in the brain of people with Parkinson's disease (PD), especially those who experience low bloo...

Minocycline in Neurocognitive Outcomes - Sickle Cell Disease

NCT ID: NCT05605366

This clinical trial is studying the effects of a medication called minocycline on cognitive decline in adults with sickle cell disease (SCD). Sickle cell disease can lead to issues with thinking, l...

Effects of Acute Pain on Motor Learning in Young vs Older Adults

NCT ID: NCT05471557

This clinical trial is studying how acute pain affects the ability to learn new movements, particularly in younger and older adults. Researchers believe that pain may make it harder for people to r...

Biomarkers Related to PSCI: An fNIRS Study

NCT ID: NCT06703307

This clinical trial, titled "Biomarkers Related to PSCI: An fNIRS Study," is focused on understanding how stroke affects thinking and memory, which is known as cognitive impairment. The researchers...

Brain Activation Pattern Caused by Immersive Virtual Reality Pathfinding Task in Stroke Patients: an FNIRS Study

NCT ID: NCT06703320

This clinical trial is studying how the brain responds to a special task using virtual reality in patients who have had a stroke. Researchers want to understand how these patients think and process...

Efficacy and Safety of Immersive Virtual Reality for Post-stroke Cognitive Impairment

NCT ID: NCT06704360

This clinical trial is studying the use of immersive virtual reality (VR) as a possible treatment for people who have experienced cognitive decline after a stroke. Cognitive decline refers to diffi...