Clinical Trials for Depression

Find clinical trials for depression. Discover research opportunities and treatment options in your area.

681 Active Trials Found

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Neuropharmacologic Imaging and Biomarker Assessments of Response to Acute and Repeated-Dosed Ketamine Infusions in Major Depressive Disorder

NCT ID: NCT03065335

This clinical trial is studying the effects of ketamine, a medication that has been shown to quickly help with depression, to see how it can be used more effectively. The main goal is to understand...

Recruiting

Phase: PHASE1 Type: interventional Locations: Bethesda, Maryland, United States, Bethesda, Maryland, United States

Community Park-Based Programs for Health Promotion: Fit2Play Prospective Cohort Study

NCT ID: NCT06595251

The Fit2Play study is looking at how a special afterschool program, which takes place in local parks, can help young people improve their fitness and mental health. This program encourages kids to ...

Recruiting

Type: observational Locations: Miami, Florida, United States

Neurobiology of Suicide

NCT ID: NCT02543983

The clinical trial titled "Neurobiology of Suicide" aims to better understand what happens in the brain of people who have thought about or attempted suicide. Researchers are studying this importan...

Recruiting

Phase: PHASE2 Type: interventional Locations: Bethesda, Maryland, United States, Bethesda, Maryland, United States

Longitudinal Deep Phenotyping of Central Mechanisms in Dysosmia: A Pilot Study Using Electrobulbogram (EBG), Functional MRI (fMRI), and Diffusion-Weighted Imaging (DWI)

NCT ID: NCT07149428

This clinical trial is studying how the brain works in people who have problems with their sense of smell, such as losing their smell completely, having a reduced sense of smell, or experiencing di...

Recruiting

Type: observational

Filipino Family Health Initiative 1.0

NCT ID: NCT06569303

The Filipino Family Health Initiative 1.0 is a study aimed at helping Filipino parents in California who may be dealing with challenges related to depression, anxiety, and parenting. The trial is t...

Recruiting

Phase: NA Type: interventional Locations: Pasadena, California, United States

Testing a Scalable Model of Care to Improve Patients Access to Mental Health Services After Traumatic Injury

NCT ID: NCT05497115

This clinical trial is looking at a program called the Trauma Resilience and Recovery Program (TRRP), which aims to help patients who have experienced traumatic injuries and may be struggling with ...

Recruiting

Phase: NA Type: interventional Locations: Washington, Virginia, United States

[18F]PF-06445974 to Image PDE4B in Major Depressive Disorder Using PET

NCT ID: NCT05703685

This clinical trial is studying a specific enzyme called PDE4B in the brains of people with Major Depressive Disorder (MDD). Researchers want to find out if they can detect levels of PDE4B using a ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Bethesda, Maryland, United States

Evaluation of Patients With Mood and Anxiety Disorders and Healthy Volunteers

NCT ID: NCT00024635

This clinical trial is looking to better understand mood and anxiety disorders by studying both patients who have these conditions and healthy volunteers. The goal is to carefully screen participan...

Recruiting

Type: observational Locations: Bethesda, Maryland, United States, Bethesda, Maryland, United States

Positive Processes and Transition to Health - Single-Session (PATH-SS)

NCT ID: NCT06900712

The Positive Processes and Transition to Health - Single Session (PATH-SS) clinical trial is studying a new type of therapy designed to help people who are dealing with distress after a sexual assa...

Recruiting

Phase: NA Type: interventional Locations: Cleveland, Ohio, United States

PET Imaging of Cyclooxygenase in Participants With Major Depressive Disorder (MDD)

NCT ID: NCT04582916

This clinical trial is studying how certain brain enzymes, called COX-1 and COX-2, are related to major depressive disorder (MDD). The researchers want to see if these enzymes are more active in th...

Recruiting

Phase: PHASE1 Type: interventional Locations: Bethesda, Maryland, United States

A Study to Assess Change in Disease Activity and Adverse Events (AEs) With Cariprazine in the Treatment of Depressive Episodes in Pediatric Participants Participants (10 to 17 Years of Age) With Bipolar I Disorder.

NCT ID: NCT04777357

This clinical trial is studying a medication called cariprazine to see how well it works for treating depressive episodes in children and teenagers aged 10 to 17 who have bipolar I disorder. Bipola...

Recruiting

Phase: PHASE3 Type: interventional Locations: Bentonville, Arkansas, United States, Anaheim, California, United States +93 more

Ecological Momentary Intervention for Reward in Anhedonia

NCT ID: NCT07155941

This clinical trial is studying a new two-week program designed to help people who have anhedonia—a condition where someone finds it hard to feel pleasure—as well as anxiety, stress, or depression....

Recruiting

Phase: NA Type: interventional

A Brief Online Mindfulness Intervention: An RCT Protocol

NCT ID: NCT05882565

This clinical trial is looking at how a short online mindfulness program can help university students in Indonesia manage stress, anxiety, and depression. Mindfulness is a technique that encourages...

Recruiting

Phase: NA Type: interventional Locations: Bandung, West Java, Indonesia

Potential Benefits of Parent Child Interaction Therapy (PCIT)

NCT ID: NCT06827951

This clinical trial is studying the benefits of Parent-Child Interaction Therapy (PCIT) for families dealing with issues like anxiety, depression, and difficulties in parent-child relationships. Th...

Recruiting

Type: observational Locations: Gainesville, Florida, United States, Jacksonville, Florida, United States

Parent Encouragement And Coaching of Happiness in Youth

NCT ID: NCT06725160

The "Parent Encouragement and Coaching of Happiness in Youth" clinical trial aims to find out how coaching parents to express positive emotions can help improve their young children's responses to ...

Not yet recruiting

Phase: NA Type: interventional Locations: Pittsburgh, Pennsylvania, United States

Impact of Gender Difference and Exercise Intensities on Depression and Anxiety Symptoms Among University Students

NCT ID: NCT07139249

This clinical trial is looking at how different levels of exercise and gender might affect symptoms of depression and anxiety in university students. The goal is to understand whether exercise inte...

Not yet recruiting

Phase: NA Type: interventional Locations: Damieta, Egypt

MOTIVATE to Improve Outcomes for Older Veterans With Musculoskeletal Pain and Depression

NCT ID: NCT05220202

The MOTIVATE trial is a study designed to help improve the health and well-being of older veterans who experience ongoing musculoskeletal pain, like chronic back pain, and also have symptoms of dep...

Recruiting

Phase: NA Type: interventional Locations: Dallas, Texas, United States, Houston, Texas, United States +1 more

Optimizing Care for Cancer Survivors With Depression: Project 3

NCT ID: NCT06930729

This clinical trial, called "Optimizing Care for Cancer Survivors With Depression: Project 3," is looking into different ways to help cancer survivors who are dealing with depression. The study wil...

Recruiting

Phase: NA Type: interventional Locations: Charleston, South Carolina, United States

Enhancing Internet-Delivered Cognitive Behaviour Therapy With Additional Content

NCT ID: NCT07095582

This clinical trial is studying whether adding extra information and support about loneliness can improve an online therapy program called the Wellbeing Course, which helps people manage symptoms o...

Recruiting

Phase: NA Type: interventional Locations: Regina, Saskatchewan, Canada

Psilocybin for Depression in People With Mild Cognitive Impairment or Early Alzheimer's Disease

NCT ID: NCT04123314

This clinical trial is exploring whether psilocybin, a hallucinogenic substance, can help reduce depression in people with Mild Cognitive Impairment (MCI) or early Alzheimer's Disease. The study ai...

Recruiting

Phase: EARLY_PHASE1 Type: interventional Locations: Baltimore, Maryland, United States

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