Clinical Trials for Depression

Find clinical trials for depression. Discover research opportunities and treatment options in your area.

701 Active Trials Found

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Investigation of the Effects of Pilates Training in Patients With Drug-Resistant Epilepsy

NCT ID: NCT06754124

This clinical trial is investigating the effects of Pilates training on patients with drug-resistant epilepsy, a condition where seizures are not well-controlled by medication. The study will invol...

Recruiting

Phase: NA Type: interventional Locations: Rize, Güneysu, Turkey, Rize, , Turkey

Neuropharmacologic Imaging and Biomarker Assessments of Response to Acute and Repeated-Dosed Ketamine Infusions in Major Depressive Disorder

NCT ID: NCT03065335

This clinical trial is studying the effects of ketamine, a medication that has been shown to quickly help with depression, to see how it can be used more effectively. The main goal is to understand...

Recruiting

Phase: PHASE1 Type: interventional Locations: Bethesda, Maryland, United States, Bethesda, Maryland, United States

Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resistant Depression

NCT ID: NCT06511908

This clinical trial is studying a new medication called (2R,6R)-hydroxynorketamine (HNK) to see if it can help people with major depressive disorder (MDD) who have not found relief from other treat...

Recruiting

Phase: PHASE2 Type: interventional Locations: Bethesda, Maryland, United States

Characterization and Treatment of Adolescent Depression

NCT ID: NCT03388606

This clinical trial is focused on understanding depression in teenagers aged 11 to 17. Researchers want to learn about the causes of depression and how it affects the brain. They aim to compare tee...

Recruiting

Type: observational Locations: Bethesda, Maryland, United States

Mechanism of Action Underlying Ketamine's Antidepressant Effects: The AMPA Throughput Theory in Patients With Treatment-Resistant Major Depression

NCT ID: NCT03973268

This clinical trial is studying how ketamine, a medication often used for depression, works in the brain. Researchers want to understand if the antidepressant effects of ketamine are linked to spec...

Recruiting

Phase: PHASE1 Type: interventional Locations: Bethesda, Maryland, United States

Reducing Psychological Barriers to PrEP Persistence Among Pregnant and Postpartum Women in Cape Town, South Africa

NCT ID: NCT05624931

This clinical trial is studying how to help pregnant and postpartum women in Cape Town, South Africa, stick with their PrEP medication to prevent HIV. PrEP is a safe and effective way to lower the ...

Recruiting

Phase: NA Type: interventional Locations: Boston, Massachusetts, United States, Cape Town, Western Cape, South Africa

Electroacupuncture on Treating Cancer-related Depression

NCT ID: NCT07003763

This clinical trial is studying how effective electroacupuncture (a treatment that uses small electrical currents with acupuncture needles) can be in helping people with cancer-related depression (...

Not yet recruiting

Phase: NA Type: interventional

The Development of an Integrated Physical Activity and Mental Health Intervention for Veterans With COPD, Emotion Distress, and Low Physical Activity

NCT ID: NCT04953806

This clinical trial is looking at how to help Veterans who have Chronic Obstructive Pulmonary Disease (COPD), along with feelings of depression and anxiety, to become more physically active. COPD i...

Recruiting

Phase: NA Type: interventional Locations: Boston, Massachusetts, United States, Boston, Massachusetts, United States

Evaluating the Role of IL-17 as an Orchestrator of Peripheral-central Cross Talk in Depressive Symptoms

NCT ID: NCT06786936

This clinical trial is focused on understanding how a specific immune response, known as IL-17, may affect depression in people who have conditions like psoriatic arthritis and psoriasis. Researche...

Recruiting

Type: observational Locations: Glasgow, Scotland, United Kingdom

Mobile CBT for Middle Aged and Older Adults

NCT ID: NCT05754151

This clinical trial is studying a mobile app called MAYA, which helps middle-aged and older adults who are dealing with anxiety and depression. The app uses techniques from cognitive behavioral the...

Recruiting

Phase: NA Type: interventional Locations: New York, New York, United States

Treatment, Emotion, and Neuromodulation of Depression (TREND) Study

NCT ID: NCT05436379

The TREND Study is a clinical trial aimed at exploring a new treatment for depression. Researchers will use a technique called theta burst stimulation (TBS), which involves gentle pulses of magneti...

Recruiting

Phase: NA Type: interventional Locations: Pittsburgh, Pennsylvania, United States

REstoring Mental Health Through COmmUnity-based Psychological Services in New York City

NCT ID: NCT04913766

This clinical trial, called "REstoring Mental Health After SARS-CoV-2 Through commUnity-based Psychological Services in New York City," aims to help improve the mental health of people, especially ...

Recruiting

Phase: NA Type: interventional Locations: New York, New York, United States

Be Well at Work-Plus: A Depression and Physical Activity Intervention for Hospital Service Workers (Aim 3)

NCT ID: NCT07010133

The "Be Well at Work-Plus" trial is studying a special program designed to help hospital service workers who are dealing with depression and may not get enough physical activity. This program will ...

Not yet recruiting

Phase: NA Type: interventional Locations: San Diego, California, United States

Financial Incentives for Veteran Therapy Completion

NCT ID: NCT06234371

This clinical trial, run by the Recovery Resource Council (RRC) in North Texas, is studying whether offering financial incentives can help veterans complete their therapy sessions. Specifically, th...

Enrolling by invitation

Phase: NA Type: interventional Locations: Dallas, Texas, United States, Denton, Texas, United States +1 more

RCT: the Effectiveness of LifeHack in Improving Mental Wellbeing in University Students.

NCT ID: NCT06423417

This clinical trial is studying a program called LifeHack, which aims to improve the mental wellbeing of university students by helping them build resilience and life skills. Many students experien...

Recruiting

Phase: NA Type: interventional Locations: Leiden, , Netherlands, Amsterdam, , Netherlands

A Study to Assess Change in Disease Activity and Adverse Events (AEs) With Cariprazine in the Treatment of Depressive Episodes in Pediatric Participants Participants (10 to 17 Years of Age) With Bipolar I Disorder.

NCT ID: NCT04777357

This clinical trial is studying a medication called cariprazine to see how well it works for treating depressive episodes in children and teenagers aged 10 to 17 who have bipolar I disorder. Bipola...

Recruiting

Phase: PHASE3 Type: interventional Locations: Bentonville, Arkansas, United States, Anaheim, California, United States +93 more

Implementation of DWM in Dutch SMEs

NCT ID: NCT06979089

This clinical trial is exploring whether an online program called Doing What Matters in Times of Stress (DWM) can help improve mental health for employees working in small and medium-sized business...

Recruiting

Phase: NA Type: interventional Locations: Amsterdam, Noord Holland, Netherlands

Neurobiology of Suicide

NCT ID: NCT02543983

The clinical trial titled "Neurobiology of Suicide" aims to better understand what happens in the brain of people who have thought about or attempted suicide. Researchers are studying this importan...

Recruiting

Phase: PHASE2 Type: interventional Locations: Bethesda, Maryland, United States, Bethesda, Maryland, United States

A Mechanistic Study to Assess a Single Dose of CYB003 in Participants With Depression and Anxiety

NCT ID: NCT06820723

This clinical trial is exploring how a single dose of a psychedelic drug, related to psilocybin (found in certain mushrooms), might help people suffering from depression and anxiety. Specifically, ...

Not yet recruiting

Phase: PHASE2 Type: interventional Locations: Columbus, Ohio, United States

Evaluation of Patients With Mood and Anxiety Disorders and Healthy Volunteers

NCT ID: NCT00024635

This clinical trial is looking to better understand mood and anxiety disorders by studying both patients who have these conditions and healthy volunteers. The goal is to carefully screen participan...

Recruiting

Type: observational Locations: Bethesda, Maryland, United States, Bethesda, Maryland, United States

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