Clinical Trials for Head and Neck Neoplasms

Dose Finding Study of Zanzalintinib With Pembrolizumab and Cetuximab in Head and Neck SCC

NCT ID: NCT06912087

This clinical trial is investigating a new treatment approach for patients with recurrent or metastatic squamous cell carcinoma of the head and neck, a type of cancer that has come back or spread a...

Laser vs Ozone Therapy for Oral Mucositis in Cancer Patients

NCT ID: NCT07069153

This clinical trial is studying two different treatments—laser therapy and ozone therapy—to help reduce the pain and mouth sores caused by oral mucositis, a common side effect of cancer treatments ...

Biospecimen Procurement for Head and Neck Disorders

NCT ID: NCT03429036

This clinical trial is focused on studying various disorders related to the head and neck, such as hearing problems and certain types of cancers. Researchers aim to collect tissue samples from pati...

First in Human Study of AZD9592 in Solid Tumors

NCT ID: NCT05647122

This clinical trial, called the First in Human Study of AZD9592, is exploring a new treatment for patients with advanced solid tumors, including types of lung, head and neck, and colorectal cancers...

The EMINENCE Study - PET/MR Imaging of Head Neck Cancer

NCT ID: NCT04612075

The EMINENCE Study is researching how advanced imaging techniques, specifically PET and MRI scans, can improve the treatment of head and neck cancers. These cancers often require radiotherapy, but ...

Head and Neck Cancer Study Project in the Geriatric Population

NCT ID: NCT06998069

This clinical trial is focused on improving treatment for older adults (aged 65 and above) with a specific type of head and neck cancer known as squamous cell carcinoma, which is at stages IB to IV...

HTL0039732 in Participants With Advanced Solid Tumours

NCT ID: NCT05944237

This clinical trial is studying a new drug called HTL0039732 to see how it works for people with advanced solid tumors, which are types of cancer that form in various organs, like the prostate, sto...

The SNAP Tool for Head and Neck Cancer Survivor-Caregiver Dyads

NCT ID: NCT05811936

This clinical trial is studying a program called the Survivorship Needs Assessment Planning (SNAP) to see how it can help both head and neck cancer survivors and their caregivers. In this study, 17...

A Study of Decreasing Radiation Therapy and Chemotherapy in People With Head and Neck Cancer

NCT ID: NCT05544136

This clinical trial is investigating a new treatment plan for people with certain types of head and neck cancer. The goal is to see if using less radiation and chemotherapy, followed by surgery to ...

NIDCD Otolaryngology Clinical Protocol Biospecimen Bank

NCT ID: NCT06303180

The NIDCD Otolaryngology Clinical Protocol Biospecimen Bank is a study aimed at understanding disorders of the head and neck, which can affect hearing, balance, taste, and other important functions...

Factors Sustaining Tobacco Abstinence in Cancer Patients Treated With Radio-chemotherapy or Radiotherapy

NCT ID: NCT06910566

The TABAC STOP ORL POUMON study is researching how to help patients with head and neck or lung cancer quit smoking for the long term. This trial is specifically looking at patients who are receivin...

Open Label Phase 2 Basket Trial With Atezolizumab and Tiragolumab in Solid Tumors

NCT ID: NCT05483400

This clinical trial is studying a combination of two immunotherapy treatments, atezolizumab and tiragolumab, for patients with certain types of solid tumors, including head and neck cancers, specif...

Photobiomodulation Therapy Plus M-health in Head and Neck Cancer Patients: LAXER Study

NCT ID: NCT05106608

The LAXER Study is looking at a treatment called Photobiomodulation (PBM) therapy to see how it can help improve the quality of life and oral health for people who have survived head and neck cance...

Heavy Strength Training in Head and Neck Cancer Survivors

NCT ID: NCT06289049

The LIFTING 2 trial is a clinical study designed to explore the effects of heavy strength training on survivors of head and neck cancer. Many people who have had this type of cancer experience ongo...

Upfront Surgery Vs Induction Chemotherapy Followed By Surgery In Oral Cancers:

NCT ID: NCT06737822

This clinical trial is investigating whether starting treatment with chemotherapy before surgery can improve outcomes for patients with advanced oral cancer. The researchers want to see if this app...

Molecular and Genomic Profiling of Head and Neck Tumors

NCT ID: NCT00200486

This clinical trial is focusing on understanding the genetic makeup of tumors found in the head and neck region. Researchers want to see how these genetic profiles relate to how well patients respo...

Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors

NCT ID: NCT04429542

This clinical trial is studying a new experimental drug called BCA101 to see how safe it is and how well it works on patients with certain types of advanced cancers that are driven by a protein cal...

Post-Operative Antibiotic Efficacy in Clean Contaminated Head and Neck Surgery: A Randomized Controlled Trial

NCT ID: NCT06672471

EMST in Patients Undergoing CRT for HNCA

NCT ID: NCT03916809

This clinical trial is studying how a special exercise program called expiratory muscle strength training (EMST) can help people with head and neck cancer maintain their ability to swallow safely a...

A Study of Pembrolizumab in Combination With Chemotherapy for Head and Neck Cancer

NCT ID: NCT05420948

This clinical trial is looking at how a blood test that measures tumor DNA can help doctors decide the best way to use chemotherapy along with a treatment called immunotherapy for patients with hea...