Clinical Trials for Myocardial Fibrosis

Find clinical trials for myocardial fibrosis. Discover research opportunities and treatment options in your area.

15 Active Trials Found

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High Relaxivity Contrast Agent for Cardiac MR in the Myocardial Scar Assessment

NCT ID: NCT05954559

This clinical trial is studying a new contrast agent called Elucirem (Gadopiclenol) for use in cardiac MRI scans, specifically to assess myocardial fibrosis, which is a condition that can cause sca...

Not yet recruiting

Phase: PHASE4 Type: interventional Locations: Baltimore, Maryland, United States

Fibrosis Assessment in Myocardial Infarction-associated Ventricular Aneurysm

NCT ID: NCT06994221

This clinical trial is studying a condition called myocardial fibrosis, which can occur after a heart attack (specifically, a type of heart attack known as STEMI or NSTEMI) that leads to the develo...

Recruiting

Type: observational Locations: Shanghai, , China

Phase IA and IB Study of AAVrh.10hFXN Gene Therapy for the Cardiomyopathy of Friedreich's Ataxia

NCT ID: NCT05302271

This clinical trial is looking at a new gene therapy called AAVrh.10hFXN to see if it can help treat heart problems caused by Friedreich's ataxia (FA), a genetic condition that affects movement and...

Recruiting

Phase: PHASE1 Type: interventional Locations: New York, New York, United States

Neprilysin Inhibition to Reduce Myocardial Fibrosis in Heart Failure With Preserved Ejection Fraction

NCT ID: NCT06536309

This clinical trial is studying a medication called sacubitril/valsartan to see if it can help reduce heart muscle scarring (myocardial fibrosis) in patients with heart failure who still have good ...

Not yet recruiting

Phase: PHASE4 Type: interventional

Triple Combination Therapy (ARNI, SGLT2i, MRA) in Advanced HFpEF

NCT ID: NCT06655480

This clinical trial is investigating a new treatment approach for patients with advanced heart failure with preserved ejection fraction (HFpEF), a condition where the heart pumps normally but has t...

Not yet recruiting

Phase: PHASE2 Type: interventional

Quantification of Myocardial Fibrosis in Aortis Stenosis

NCT ID: NCT06571175

This clinical trial is looking at how heart muscle changes over time in patients with aortic valve stenosis, a condition where the heart's aortic valve becomes narrowed, affecting blood flow. The s...

Not yet recruiting

Type: observational Locations: Trondheim, Trøndelag, Norway, Trondheim, , Norway

SPECT Fibroblast Activation Protein Imaging in Patients With Cardiac Disease

NCT ID: NCT06326970

This clinical trial is looking at a special type of imaging called 99mTc-FAPI to better understand heart diseases, especially those related to heart tissue damage or fibrosis. Researchers want to s...

Not yet recruiting

Type: observational

Liver Disease, Myocardial Fibrosis and Collaterals in the Adult Fontan Patient a Metabolomics and Proteomics Approach

NCT ID: NCT04764305

This clinical trial is focused on understanding how certain health issues, like liver disease and heart problems, develop in adults who have a special type of heart circulation called Fontan circul...

Recruiting

Type: observational Locations: Innsbruck, , Austria

Losartan in Prevention of Radiation-Induced Heart Failure

NCT ID: NCT05607017

This clinical trial is studying whether a medication called losartan can help prevent heart problems caused by radiation therapy in women with non-metastatic breast cancer. Radiation therapy is a c...

Recruiting

Phase: EARLY_PHASE1 Type: interventional Locations: Boston, Massachusetts, United States

Ultrahypofractionation and Normal Tissue Toxicity

NCT ID: NCT05912231

This clinical trial is investigating whether a type of radiation therapy called proton beam therapy (PBT) is better for protecting the heart compared to traditional photon radiation therapy (XRT) i...

Recruiting

Phase: NA Type: interventional Locations: Boston, Massachusetts, United States

Effects of Aortic Valve Replacement on Myocardial T1 Values in Severe Aortic Valve Stenosis

NCT ID: NCT05404100

This clinical trial is studying how aortic valve replacement (AVR) affects heart tissue changes in patients with severe aortic valve stenosis, a condition where the heart's aortic valve becomes nar...

Recruiting

Type: observational Locations: Copenhagen O, , Denmark

The Effect of Henagliflozin and Metformin on Myocardial Tissue-level Characteristics

NCT ID: NCT06059287

This clinical trial is studying the effects of two medications, henagliflozin and metformin, on heart tissue in patients with type 2 diabetes and obesity. The goal is to see how these drugs may hel...

Not yet recruiting

Phase: NA Type: interventional

Evaluate Aerobic Exercise on Myocardial Fibrosis and Intestinal Flora in Dilated Cardiomyopathy Diagnosed First Time.

NCT ID: NCT06039969

This clinical trial is studying the effects of aerobic exercise on patients who have been diagnosed for the first time with dilated cardiomyopathy, a condition that affects the heart's ability to p...

Recruiting

Type: observational Locations: Huai'an, Jiangsu, China

Response of the Myocardium to Hypertrophic Conditions in the Adult Population

NCT ID: NCT02670031

This clinical trial is studying how the heart responds to conditions that cause thickening of the heart muscle, particularly in people with high blood pressure. The focus is on understanding a spec...

Recruiting

Type: observational Locations: Singapore, , Singapore

Study of Novel PET Tracer Gallium [68Ga]/ Fluorine [18F] -FAPI-04 in the Diagnosis of Cardiovascular Diseases

NCT ID: NCT05867589

This clinical trial is studying a new imaging agent called 68Ga/18F-FAPI-04, which is designed to help doctors see and diagnose heart conditions, specifically a problem known as myocardial fibrosis...

Recruiting

Phase: NA Type: interventional Locations: Nanjing, Jiangsu, China

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