Clinical Trials for Normal Physiology

MRS Measurement of Glutamate and GABA Metabolism in Brain

NCT ID: NCT00109174

This clinical trial is studying how the brain processes important chemicals called neurotransmitters, specifically glutamate (which helps send signals in the brain) and GABA (which helps calm signa...

Sociocultural & Biobehavioral Influences on Pain Expression and Assessment

NCT ID: NCT03258580

This clinical trial is exploring how social and cultural factors affect the way people experience and express pain. Researchers want to understand if these factors change how we interpret pain in o...

Perception, Sensation, Cognition and Action in Humans

NCT ID: NCT03407066

This clinical trial is investigating how healthy adults understand what they see and hear, focusing on the brain's processes for turning visual and auditory signals into perceptions and thoughts. T...

Developing Transcranial Neuromodulation Protocols for Learning and Decision-Making

NCT ID: NCT06561828

This clinical trial is investigating a technique called transcranial magnetic stimulation (TMS) to see if it can change brain activity in ways that might help individuals with substance use disorde...

Addictions Neuroclinical Assessment (ANA)

NCT ID: NCT04946851

Investigating the Impact of Obesity on Pubertal Development in Girls

NCT ID: NCT02583646

This clinical trial is studying whether overweight girls start puberty earlier than girls who are a normal weight. Researchers believe that some changes, like breast development, may happen sooner ...

Development of 3T Magnetic Resonance Research Methods for NIA Studies

NCT ID: NCT01324206

This clinical trial is focused on improving a special type of MRI scan using a new machine called the 3T MRI scanner. MRI scans are important tools that help doctors see the structure and function ...

Development Of Neuroimaging Methods To Assess The Neurobiology Of Addiction

NCT ID: NCT02535702

This clinical trial is focused on understanding how addiction affects the brain by using a technique called magnetic resonance imaging (MRI). Researchers want to develop new ways to use MRI to capt...

Energy Expenditure Responses to Different Temperatures

NCT ID: NCT01568671

This clinical trial is studying how our bodies burn calories at different temperatures, specifically looking at a type of fat called brown fat that helps keep us warm. Researchers want to see if be...

Characterization of an Optically Pumped Magnetometer (OPM) Magnetoencephalography (MEG) Array

NCT ID: NCT04950309

This clinical trial is studying a new type of sensor called an Optically Pumped Magnetometer (OPM) that can measure the magnetic fields produced by brain activity. The goal is to see how well this ...

Functional Magnetic Resonance Imaging Sleep Study With Auditory Stimuli

NCT ID: NCT02629107

This clinical trial is studying how our brains react to sounds while we sleep, using advanced imaging techniques called functional magnetic resonance imaging (fMRI) and electroencephalogram (EEG). ...

Development of Non-Invasive Brain Stimulation Techniques

NCT ID: NCT03351764

This clinical trial is studying non-invasive brain stimulation (NIBS) techniques to better understand how they can be used to diagnose and treat mental health and neurological conditions. The goal ...

Defining Neurobiological Links Between Substance Use and Mental Illness

NCT ID: NCT05538910

This clinical trial is studying how nicotine affects people with major depressive disorder (MDD) and how it relates to their brain function. Researchers want to learn more about why people with MDD...

Brain Dopaminergic Signaling in Opioid Use Disorders

NCT ID: NCT03190954

This clinical trial is investigating how opioid use affects a brain chemical called dopamine, which plays a role in self-control and impulsiveness. Researchers want to understand whether lower leve...

Assessing and Improving Quantitative Magnetic Resonance Imaging Metrics in Human Subjects

NCT ID: NCT05604534

This clinical trial is studying how to improve magnetic resonance imaging (MRI) technology by collecting scans from healthy individuals. MRI is a medical tool that creates detailed images of the in...

Development and Validation of Learning and Decision-Making Tasks

NCT ID: NCT05707806

This clinical trial is studying how people learn and make decisions, particularly in the context of substance use disorders. Researchers are trying to create tests that can help us understand these...

NIEHS Repository of Stored Biological Samples for Future Use

NCT ID: NCT05666739

This clinical trial, called the NIEHS Repository of Stored Biological Samples for Future Use, is focused on collecting blood and urine samples from healthy individuals to help researchers improve l...

Impact of Sex and Age on Non-visual Light Input That Affects Sleep and Circadian Rhythms

NCT ID: NCT05829044

This clinical trial is exploring how our eyes respond to different types of light and how this affects our sleep and daily rhythms, particularly looking at how these responses might differ based on...

Clinical and Scientific Assessment of Pain and Painful Disorders

NCT ID: NCT02707029

This clinical trial aims to better understand pain and how it affects people by studying both those who experience pain and those who do not. Researchers will ask participants about their pain expe...

The Effects of Increasing Caloric Intake on Diet-Induced Thermogenesis and 24h Energy Expenditure

NCT ID: NCT05545306

This clinical trial is studying how different diets affect the body's energy use, particularly focusing on a process called diet-induced thermogenesis (DIT). DIT is the energy your body burns when ...