A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease

NCT ID: NCT06283966

This clinical trial is studying a new inhaler that combines three medications—budesonide, glycopyrronium, and formoterol—to see how well it works in improving heart and lung health in people with C...

Recruiting

Phase: PHASE3 Conditions: COPD (Chronic Obstructive Pulmonary Disease)

LIVERAGE™: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver Fibrosis

NCT ID: NCT06632444

The LIVERAGE™ clinical trial is studying a medication called survodutide to see if it can help adults with a liver disease known as Metabolic Dysfunction Associated Steatohepatitis (MASH) who also ...

Recruiting

Phase: PHASE3 Conditions: Liver Fibrosis, Metabolic Dysfunction Associated Steatohepatitis (MASH)

Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)

NCT ID: NCT03486873

This clinical trial, called MK-3475-587, is looking into the long-term safety and effectiveness of a treatment called pembrolizumab (also known as MK-3475) for patients with advanced tumors. If you...

Recruiting

Phase: PHASE3 Conditions: Solid Tumors, Hematologic Malignancies

A Dose-Escalation and Expansion Study of BGB-16673 in Participants With B-Cell Malignancies

NCT ID: NCT05006716

This clinical trial is studying a new treatment called BGB-16673 for patients with specific types of B-cell cancers, such as Marginal Zone Lymphoma, Follicular Lymphoma, and Chronic Lymphocytic Leu...

Recruiting

Phase: PHASE1 Conditions: Chronic Lymphocytic Leukemia, Mantle Cell Lymphoma +7 more

Efficacy and Safety of Subcutaneous Dupilumab for the Treatment of Adult Participants With Chronic Pruritus of Unknown Origin (CPUO) (LIBERTY-CPUO-CHIC)

NCT ID: NCT05263206

This clinical trial, called LIBERTY-CPUO-CHIC, is studying a treatment called dupilumab for adults who experience severe itching, known as chronic pruritus of unknown origin (CPUO). The main goal i...

Recruiting

Phase: PHASE3 Conditions: Pruritus

A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple Myeloma

NCT ID: NCT05552222

This clinical trial is studying two combinations of medications for patients with newly diagnosed multiple myeloma, a type of blood cancer. The combinations being tested are teclistamab with daratu...

Recruiting

Phase: PHASE3 Conditions: Multiple Myeloma

Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial)

NCT ID: NCT05554393

This clinical trial, called the MyeloMATCH Treatment Trial, is studying different treatment combinations for younger patients with a type of blood cancer known as acute myeloid leukemia (AML). The ...

Recruiting

Phase: PHASE2 Conditions: Acute Myeloid Leukemia

Testing the Effects of Novel Therapeutics for Newly Diagnosed, Untreated Patients With High-Risk Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)

NCT ID: NCT05554406

This clinical trial, called the MyeloMATCH Treatment Trial, is investigating different treatment options for adults who have recently been diagnosed with a serious form of blood cancer called high-...

Recruiting

Phase: PHASE2 Conditions: Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm +2 more

A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab

NCT ID: NCT05675410

This clinical trial is studying whether adding two specific drugs, brentuximab vedotin and nivolumab, to the standard treatment for early-stage Hodgkin lymphoma can help patients live longer and ex...

Recruiting

Phase: PHASE3 Conditions: Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8

A Study to Compare Darolutamide Given With Androgen Deprivation Therapy (ADT) With ADT in Men With Hormone Sensitive Prostate Cancer and Raise of Prostate Specific Antigen (PSA) Levels After Local Therapies

NCT ID: NCT05794906

This clinical trial is studying a new treatment approach for men who have hormone-sensitive prostate cancer that has returned after initial treatment, indicated by rising levels of a protein called...

Recruiting

Phase: PHASE3 Conditions: Biochemically Recurrent Prostate Cancer

An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan Versus Observation in PSMA Positive OMPC.

NCT ID: NCT05939414

This clinical trial is studying a new treatment called lutetium (177Lu) vipivotide tetraxetan for men with oligometastatic prostate cancer (OMPC), which means their cancer has spread to a few place...

Recruiting

Phase: PHASE3 Conditions: Oligometastatic Prostate Cancer (OMPC)

Study of Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Obinutuzumab in Participants With Chronic Lymphocytic Leukemia (CLL)

NCT ID: NCT06073821

This clinical trial is studying the effectiveness of two different treatment combinations for people with chronic lymphocytic leukemia (CLL), a type of cancer that affects the blood and bone marrow...

Recruiting

Phase: PHASE3 Conditions: CLL

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

NCT ID: NCT06172296

This clinical trial is studying a new treatment approach for children with high-risk neuroblastoma, a type of cancer that affects nerve cells. The researchers want to find out if combining a medici...

Recruiting

Phase: PHASE3 Conditions: Neuroblastoma, Ganglioneuroblastoma, Nodular

A Study of Upadacitinib in Adult Participants With Moderate-to-Severe Atopic Dermatitis and Inadequate Response to Dupilumab

NCT ID: NCT06389136

This clinical trial is studying a medication called upadacitinib for adults with moderate to severe atopic dermatitis (AD), a skin condition that causes rashes and itching. The trial aims to find o...

Recruiting

Phase: PHASE3 Conditions: Atopic Dermatitis

A Study to Compare the Efficacy and Safety of BMS-986393 Versus Standard Regimens in Adult Participants With Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma (QUINTESSENTIAL-2)

NCT ID: NCT06615479

This clinical trial, called QUINTESSENTIAL-2, is testing a new treatment called BMS-986393 to see how well it works compared to standard treatments for adults with relapsed or refractory multiple m...

Recruiting

Phase: PHASE3 Conditions: Relapsed or Refractory Multiple Myeloma (RRMM)

DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

NCT ID: NCT06989112

The DESTINY-Endometrial01 trial is a research study looking at new treatment options for women with a specific type of advanced or recurrent endometrial cancer, which is a cancer of the uterus. Thi...

Recruiting

Phase: PHASE3 Conditions: Endometrial Cancer

A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

NCT ID: NCT07064473

This clinical trial is studying whether a new medicine called vicadrostat, when taken together with an existing diabetes medicine called empagliflozin, can help lower the risk of heart problems in ...

Recruiting

Phase: PHASE3 Conditions: Hypertension, Diabetes Mellitus, Type 2 +1 more

Program to Assess Adverse Events and Change in Disease Activity of Oral Upadacitinib in Adult Participants With Moderate to Severe Systemic Lupus Erythematosus

NCT ID: NCT05843643

This clinical trial is studying the safety and effectiveness of a medication called upadacitinib for adults with moderate to severe systemic lupus erythematosus (SLE), a disease that causes inflamm...

Recruiting

Phase: PHASE3 Conditions: Systemic Lupus Erythematosus

ELEMENT-MDS: A Study to Compare the Efficacy and Safety of Luspatercept in Participants With Myelodysplastic Syndrome (MDS) and Anemia Not Receiving Blood Transfusions

NCT ID: NCT05949684

The ELEMENT-MDS clinical trial is studying how effective and safe a medication called Luspatercept is for treating anemia in adults with Myelodysplastic Syndromes (MDS) who are not receiving blood ...

Recruiting

Phase: PHASE3 Conditions: Myelodysplastic Syndromes

IRI-EXPLORE: A Study to Test Whether BI 765845 Helps People Who Have Had a Heart Attack

NCT ID: NCT06139328

The IRI-EXPLORE trial is studying a medication called BI 765845 to see if it can help people who have recently had a heart attack. This trial is open to adults aged 18 and older who have experience...

Recruiting

Phase: PHASE2 Conditions: Myocardial Infarction

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Clinical Trials in Calgary, Alberta

566 Active Trials Found in Calgary

A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease

LIVERAGE™: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver Fibrosis

Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)

A Dose-Escalation and Expansion Study of BGB-16673 in Participants With B-Cell Malignancies

Efficacy and Safety of Subcutaneous Dupilumab for the Treatment of Adult Participants With Chronic Pruritus of Unknown Origin (CPUO) (LIBERTY-CPUO-CHIC)

A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple Myeloma

Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial)

Testing the Effects of Novel Therapeutics for Newly Diagnosed, Untreated Patients With High-Risk Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)

A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab

A Study to Compare Darolutamide Given With Androgen Deprivation Therapy (ADT) With ADT in Men With Hormone Sensitive Prostate Cancer and Raise of Prostate Specific Antigen (PSA) Levels After Local Therapies

An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan Versus Observation in PSMA Positive OMPC.

Study of Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Obinutuzumab in Participants With Chronic Lymphocytic Leukemia (CLL)

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

A Study of Upadacitinib in Adult Participants With Moderate-to-Severe Atopic Dermatitis and Inadequate Response to Dupilumab

A Study to Compare the Efficacy and Safety of BMS-986393 Versus Standard Regimens in Adult Participants With Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma (QUINTESSENTIAL-2)

DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

Program to Assess Adverse Events and Change in Disease Activity of Oral Upadacitinib in Adult Participants With Moderate to Severe Systemic Lupus Erythematosus

ELEMENT-MDS: A Study to Compare the Efficacy and Safety of Luspatercept in Participants With Myelodysplastic Syndrome (MDS) and Anemia Not Receiving Blood Transfusions

IRI-EXPLORE: A Study to Test Whether BI 765845 Helps People Who Have Had a Heart Attack