A Study of AMG 193 in Participants With Advanced MTAP-null Solid Tumors (MTAPESTRY 101)

NCT ID: NCT05094336

This clinical trial is studying a new treatment called AMG 193 for adults with advanced solid tumors that have a specific genetic change known as MTAP-null. The main goals of the study are to find ...

Recruiting

Phase: PHASE1 Conditions: Advanced MTAP-null Solid Tumors

A Study to Learn About the Study Medicine Called PF-07799544 in People With Advanced Solid Tumors

NCT ID: NCT05538130

This clinical trial is studying a new medicine called PF-07799544 to see how safe and effective it is for people with advanced solid tumors, such as melanoma, brain cancer, thyroid cancer, and lung...

Recruiting

Phase: PHASE1 Conditions: Colorectal Cancer, Melanoma +5 more

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

NCT ID: NCT05564390

The MYELOMATCH trial is a research study designed to help people with certain types of blood cancers, specifically acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). The main goal of ...

Recruiting

Phase: PHASE2 Conditions: Acute Myeloid Leukemia, Myelodysplastic Syndrome

A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab

NCT ID: NCT05675410

This clinical trial is studying whether adding two specific drugs, brentuximab vedotin and nivolumab, to the standard treatment for early-stage Hodgkin lymphoma can help patients live longer and ex...

Recruiting

Phase: PHASE3 Conditions: Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8

A Study to Assess Long-term Safety, Tolerability, and Efficacy of Rocatinlimab in Adult and Adolescent Participants With Moderate-to-severe Atopic Dermatitis (AD)

NCT ID: NCT05882877

This clinical trial is studying a medication called rocatinlimab to see how safe it is and how well it works for people aged 12 and older who have moderate to severe atopic dermatitis, which is a t...

Recruiting

Phase: PHASE3 Conditions: Atopic Dermatitis

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

NCT ID: NCT06172296

This clinical trial is studying a new treatment approach for children with high-risk neuroblastoma, a type of cancer that affects nerve cells. The researchers want to find out if combining a medici...

Recruiting

Phase: PHASE3 Conditions: Neuroblastoma, Ganglioneuroblastoma, Nodular

Study to Evaluate Avacopan in Combination With a Rituximab or Cyclophosphamide-containing Regimen, in Children From 6 Years to < 18 Years of Age With AAV.

NCT ID: NCT06321601

This clinical trial is studying a new medication called avacopan to see how well it works when used with treatments like rituximab or cyclophosphamide in children aged 6 to 17 who have a specific t...

Recruiting

Phase: PHASE3 Conditions: Vasculitis

A Study to Evaluate the Efficacy and Safety of Autogene Cevumeran With Nivolumab Versus Nivolumab Alone in Participants With High-Risk Muscle-Invasive Urothelial Carcinoma (MIUC)

NCT ID: NCT06534983

This clinical trial is investigating the effectiveness and safety of a new treatment called autogene cevumeran when used alongside nivolumab for patients with high-risk muscle-invasive urothelial c...

Recruiting

Phase: PHASE2 Conditions: Muscle Invasive Urothelial Carcinoma

A Study to Compare the Efficacy and Safety of BMS-986489 (BMS-986012+ Nivolumab Fixed Dose Combination) in Combination With Carboplatin Plus Etoposide to That of Atezolizumab With Carboplatin Plus Etoposide as First-Line Therapy in Participants With Extensive-Stage Small Cell Lung Cancer (TIGOS).

NCT ID: NCT06646276

This clinical trial, called TIGOS, is studying a new treatment for people with Extensive-Stage Small Cell Lung Cancer (ES-SCLC). The researchers want to compare two treatment combinations: one that...

Recruiting

Phase: PHASE3 Conditions: Extensive-Stage Small Cell Lung Cancer

Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancer

NCT ID: NCT01810913

This clinical trial is exploring new treatment options for patients with high-risk head and neck cancers, specifically those that begin in the thin, flat cells called squamous cells. The researcher...

Recruiting

Phase: PHASE2 Conditions: Stage III Oropharyngeal Squamous Cell Carcinoma AJCC v7, Stage IV Hypopharyngeal Squamous Cell Carcinoma AJCC v7 +7 more

Pan Tumor Rollover Study

NCT ID: NCT03899155

The Pan Tumor Rollover Study is a clinical trial focused on understanding the long-term safety of a cancer treatment called nivolumab, both on its own and in combination with other therapies. This ...

Recruiting

Phase: PHASE2 Conditions: Cancer

Antibiotic Prophylaxis for Bladder Botox

NCT ID: NCT04444440

This clinical trial is investigating whether taking antibiotics before and after receiving Botox injections in the bladder can help prevent urinary infections that sometimes occur after the procedu...

Recruiting

Phase: PHASE4 Conditions: Idiopathic Overactive Bladder, Postoperative Urinary Tract Infection

A Study to Learn About the Study Medicine Elranatamab Alone and With Daratumumab in People With Multiple Myeloma Who Have Received Other Treatments

NCT ID: NCT05020236

The MagnetisMM-5 clinical trial is studying a new treatment option for people with relapsed or refractory multiple myeloma, a type of blood cancer. Researchers want to see if a medication called el...

Recruiting

Phase: PHASE3 Conditions: Multiple Myeloma

Oral Sildenafil for Exercise Capacity, Dyspnea and Cardiopulmonary Function in COPD

NCT ID: NCT05061368

This clinical trial is studying the effects of a medication called sildenafil on patients with mild Chronic Obstructive Pulmonary Disease (COPD). COPD is a lung condition that makes it hard to brea...

Recruiting

Phase: PHASE2 Conditions: Chronic Obstructive Pulmonary Disease

A Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced Solid Tumors With BRAF Alterations.

NCT ID: NCT05355701

This clinical trial is studying a new medicine called PF-07799933 to see how safe it is and how well it works for people with advanced solid tumors that have a specific gene change known as a "BRAF...

Recruiting

Phase: PHASE1 Conditions: Melanoma, Glioma +2 more

Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants

NCT ID: NCT05589714

The Universal Rare Gene Study is a research project aimed at understanding rare genetic causes of retinal dystrophies, like inherited retinal degeneration and retinitis pigmentosa. This internation...

Recruiting

Conditions: Retinitis Pigmentosa, Inherited Retinal Degeneration

A Multicentre, Randomised, Double-blind, Parallel Group, Placebo-controlled, Time-to-first Asthma Exacerbation Phase III Efficacy and Safety Study of Benralizumab in Paediatric Patients With Severe Eosinophilic Asthma (DOMINICA)

NCT ID: NCT05692180

The DOMINICA study is a clinical trial designed to evaluate the effectiveness and safety of a medication called benralizumab for children and teenagers aged 6 to 17 years who suffer from severe eos...

Recruiting

Phase: PHASE3 Conditions: Asthma

A Study With Tovorafenib (DAY101) as a Treatment Option for Progressive, Relapsed, or Refractory Langerhans Cell Histiocytosis

NCT ID: NCT05828069

This clinical trial is studying a new treatment called tovorafenib (DAY101) for patients with a condition known as Langerhans cell histiocytosis (LCH). This disease occurs when the body produces to...

Recruiting

Phase: PHASE2 Conditions: Recurrent Langerhans Cell Histiocytosis, Refractory Langerhans Cell Histiocytosis

Program to Assess Adverse Events and Change in Disease Activity of Oral Upadacitinib in Adult Participants With Moderate to Severe Systemic Lupus Erythematosus

NCT ID: NCT05843643

This clinical trial is studying the safety and effectiveness of a medication called upadacitinib for adults with moderate to severe systemic lupus erythematosus (SLE), a disease that causes inflamm...

Recruiting

Phase: PHASE3 Conditions: Systemic Lupus Erythematosus

A Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-TNF Therapy

NCT ID: NCT05889182

This clinical trial is studying a medication called upadacitinib to see how effective and safe it is for treating moderate to severe hidradenitis suppurativa (HS) in adults and adolescents who have...

Recruiting

Phase: PHASE3 Conditions: Hidradenitis Suppurativa

Main Menu

Clinical Trials in Edmonton, Alberta

606 Active Trials Found in Edmonton

A Study of AMG 193 in Participants With Advanced MTAP-null Solid Tumors (MTAPESTRY 101)

A Study to Learn About the Study Medicine Called PF-07799544 in People With Advanced Solid Tumors

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab

A Study to Assess Long-term Safety, Tolerability, and Efficacy of Rocatinlimab in Adult and Adolescent Participants With Moderate-to-severe Atopic Dermatitis (AD)

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

Study to Evaluate Avacopan in Combination With a Rituximab or Cyclophosphamide-containing Regimen, in Children From 6 Years to < 18 Years of Age With AAV.

A Study to Evaluate the Efficacy and Safety of Autogene Cevumeran With Nivolumab Versus Nivolumab Alone in Participants With High-Risk Muscle-Invasive Urothelial Carcinoma (MIUC)

A Study to Compare the Efficacy and Safety of BMS-986489 (BMS-986012+ Nivolumab Fixed Dose Combination) in Combination With Carboplatin Plus Etoposide to That of Atezolizumab With Carboplatin Plus Etoposide as First-Line Therapy in Participants With Extensive-Stage Small Cell Lung Cancer (TIGOS).

Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancer

Pan Tumor Rollover Study

Antibiotic Prophylaxis for Bladder Botox

A Study to Learn About the Study Medicine Elranatamab Alone and With Daratumumab in People With Multiple Myeloma Who Have Received Other Treatments

Oral Sildenafil for Exercise Capacity, Dyspnea and Cardiopulmonary Function in COPD

A Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced Solid Tumors With BRAF Alterations.

Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants

A Multicentre, Randomised, Double-blind, Parallel Group, Placebo-controlled, Time-to-first Asthma Exacerbation Phase III Efficacy and Safety Study of Benralizumab in Paediatric Patients With Severe Eosinophilic Asthma (DOMINICA)

A Study With Tovorafenib (DAY101) as a Treatment Option for Progressive, Relapsed, or Refractory Langerhans Cell Histiocytosis

Program to Assess Adverse Events and Change in Disease Activity of Oral Upadacitinib in Adult Participants With Moderate to Severe Systemic Lupus Erythematosus

A Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-TNF Therapy