Clinical Trials in Jonesboro, Arkansas

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-Small Cell Lung Cancer, ALCHEMIST Trial

NCT ID: NCT04267848

The ALCHEMIST trial is a clinical study looking at whether adding a drug called pembrolizumab, which is a type of immunotherapy, to standard chemotherapy can improve treatment outcomes for patients...

A Study of Imlunestrant Versus Standard Endocrine Therapy in Participants With Early Breast Cancer

NCT ID: NCT05514054

This clinical trial is studying a new treatment called imlunestrant to see how well it works compared to standard hormone therapy for patients with early breast cancer. The patients being considere...

Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial

NCT ID: NCT06498635

The INSIGHT Trial is a research study looking at whether an immunotherapy drug called durvalumab can help prevent lung cancer from returning after surgery. This trial includes patients who have had...

Repeat Ablation of Persistent Atrial Fibrillation, Including Mitral Isthmus Catheter Ablation, With the FARAPULSE Pulsed Field Ablation System

NCT ID: NCT06735534

The ReMATCH Study is a clinical trial that is looking at a new treatment method for patients with persistent atrial fibrillation (AF), a condition where the heart beats irregularly. This study aims...

Gedatolisib Plus Fulvestrant With or Without Palbociclib vs Standard-of-Care for the Treatment of Patients With Advanced or Metastatic HR+/HER2- Breast Cancer (VIKTORIA-1)

NCT ID: NCT05501886

The VIKTORIA-1 trial is studying a new treatment for people with advanced or metastatic HR+/HER2- breast cancer, specifically looking at how well a combination of gedatolisib and fulvestrant works,...

Program to Assess Adverse Events and Change in Disease Activity of Oral Upadacitinib in Adult Participants With Moderate to Severe Systemic Lupus Erythematosus

NCT ID: NCT05843643

This clinical trial is studying the safety and effectiveness of a medication called upadacitinib for adults with moderate to severe systemic lupus erythematosus (SLE), a disease that causes inflamm...

Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer

NCT ID: NCT04181060

This clinical trial is studying the effects of two treatments for patients with advanced non-small cell lung cancer that has a specific gene change called an EGFR mutation. Researchers want to find...

Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer

NCT ID: NCT06058377

This clinical trial is examining whether an immunotherapy drug called durvalumab can be added to standard chemotherapy treatments for patients with stage II-III hormone receptor positive, HER2 nega...

A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer

NCT ID: NCT06662786

This clinical trial is examining two different treatment options for adults with advanced left-sided colorectal cancer that cannot be surgically removed. The researchers want to find out which trea...

A Study to Evaluate the Efficacy and Safety of Icotrokinra (JNJ-77242113) in Biologic-experienced Participants With Active Psoriatic Arthritis

NCT ID: NCT06807424

This clinical trial is studying a new medication called icotrokinra to see how well it works and how safe it is for people with active psoriatic arthritis (PsA) who have already tried other biologi...

Testing the Addition of Radiation Therapy to the Usual Immune Therapy Treatment (Atezolizumab) for Extensive Stage Small Cell Lung Cancer, The RAPTOR Trial

NCT ID: NCT04402788

The RAPTOR Trial is a clinical study looking at whether adding radiation therapy to the usual treatment with atezolizumab can help patients with extensive stage small cell lung cancer. This type of...

APOLLO: A Randomized Phase II Double-Blind Study of Olaparib Versus Placebo Following Curative Intent Therapy in Patients With Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 Mutation

NCT ID: NCT04858334

The APOLLO trial is studying the effects of a medication called olaparib in patients who have had surgery for pancreatic cancer and have specific genetic mutations (in genes called BRCA1, BRCA2, or...

A Pivotal Investigational Device Exemption Study on Laminar Left Atrial Appendage Elimination

NCT ID: NCT06168942

This clinical trial is studying a new device called the Laminar Left Atrial Appendage Closure (LAAC) device. The goal is to see how safe and effective this device is compared to existing LAAC devic...

A Registry Based Collaborative to Measure Efficiency, Effectiveness, and Safety of Farapulse PFA Technology for AF

NCT ID: NCT06335082

Olanzapine Versus Megestrol Acetate for the Treatment of Loss of Appetite Among Advanced Cancer Patients

NCT ID: NCT04939090

This clinical trial is studying two medications, olanzapine and megestrol acetate, to see which one is more effective at helping cancer patients with advanced disease who are experiencing a loss of...

Study of Romiplostim for Chemotherapy-induced Thrombocytopenia in Adult Subjects With Non-small Cell Lung Cancer (NSCLC), Ovarian Cancer, or Breast Cancer

NCT ID: NCT03937154

This clinical trial is studying a medication called romiplostim to see how effective it is in helping patients with certain types of cancer—specifically non-small cell lung cancer, ovarian cancer, ...

Drug-Eluting Registry: Real-World Treatment of Lesions in the Peripheral Vasculature

NCT ID: NCT04674969

The ELEGANCE Registry is a clinical trial that aims to gather important information about the real-world use of drug-eluting devices made by Boston Scientific for treating peripheral vascular disea...

Study of Radiation Therapy Followed by Atezolizumab in Stage II or III Non-small Cell Lung Cancer Patients

NCT ID: NCT04310020

This clinical trial is investigating a new treatment approach for patients with stage II or III non-small cell lung cancer (NSCLC). The study will look at how effective and safe it is to use radiat...

Safety and Effectiveness of the Globe® Pulsed Field System for Treating Patients With Symptomatic Paroxysmal or Persistent Atrial Fibrillation

NCT ID: NCT05462145

This clinical trial is studying a new treatment called the Globe® Pulsed Field System for patients with symptomatic paroxysmal or persistent atrial fibrillation (AF). Atrial fibrillation is a commo...

SIMPLAAFY Clinical Trial

NCT ID: NCT06521463

The SIMPLAAFY Clinical Trial is studying the safety and effectiveness of two single-drug treatments compared to a combination of two antiplatelet drugs for patients who have received a WATCHMAN FLX...