Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study

NCT ID: NCT05987241

The MODERN study is a clinical trial designed to explore how a blood test can help identify bladder cancer patients who may need additional treatment after having their bladder surgically removed. ...

Recruiting

Phase: PHASE2 Conditions: Stage III Bladder Urothelial Carcinoma AJCC v6 and v7, Stage IV Bladder Urothelial Carcinoma AJCC v7 +5 more

Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab

NCT ID: NCT05812807

This clinical trial is studying whether the immunotherapy drug pembrolizumab is more effective than simply observing patients after surgery for early-stage triple-negative breast cancer. The trial ...

Recruiting

Phase: PHASE3 Conditions: Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 +2 more

A Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-TNF Therapy

NCT ID: NCT05889182

This clinical trial is studying a medication called upadacitinib to see how effective and safe it is for treating moderate to severe hidradenitis suppurativa (HS) in adults and adolescents who have...

Recruiting

Phase: PHASE3 Conditions: Hidradenitis Suppurativa

Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial

NCT ID: NCT06096844

The ACHIEVE Trial is a clinical study designed to find out if combining chemotherapy with an immunotherapy drug called pembrolizumab is more effective than using immunotherapy alone for older adult...

Recruiting

Phase: PHASE3 Conditions: Stage IV Lung Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8 +2 more

A Study of Barzolvolimab in Patients With Prurigo Nodularis

NCT ID: NCT06366750

This clinical trial is studying a new treatment called barzolvolimab for adults with prurigo nodularis, a condition that causes itchy, raised nodules on the skin. The main goal is to see how effect...

Recruiting

Phase: PHASE2 Conditions: Prurigo Nodularis

Efficacy and Safety Study of BHV-7000 Monotherapy in Major Depression

NCT ID: NCT06419608

This clinical trial is studying a new treatment called BHV-7000 for people with Major Depressive Disorder (MDD). The goal is to see how well this treatment works and how safe it is for individuals ...

Recruiting

Phase: PHASE2 Conditions: Major Depressive Disorder

A Study of Sigvotatug Vedotin in Advanced Solid Tumors

NCT ID: NCT04389632

This clinical trial is studying a new drug called sigvotatug vedotin (SGN-B6A) to see how safe it is and if it can help treat various advanced solid tumors, such as lung cancer, breast cancer, and ...

Recruiting

Phase: PHASE1 Conditions: Ovarian Neoplasms, Esophageal Squamous Cell Carcinoma +10 more

Testing the Addition of the AKT Inhibitor, Ipatasertib, to Treatment With the Hormonal Agent Megestrol Acetate for Recurrent or Metastatic Endometrial Cancers

NCT ID: NCT05538897

This clinical trial is studying a new treatment approach for women with recurrent or metastatic endometrial cancer, which is a type of cancer that starts in the lining of the uterus. The trial is t...

Recruiting

Phase: PHASE1 Conditions: Recurrent Endometrial Endometrioid Adenocarcinoma, FIGO Grade 1 Endometrial Endometrioid Adenocarcinoma +2 more

A Study to Evaluate the Long-Term Safety and Efficacy of Povorcitinib in Participants With Moderate to Severe Hidradenitis Suppurativa

NCT ID: NCT06212999

This clinical trial is looking at the long-term safety and effectiveness of a medication called povorcitinib for people with moderate to severe hidradenitis suppurativa (HS), a skin condition that ...

Recruiting

Phase: PHASE3 Conditions: Hidradenitis Suppurativa (HS)

Rollover Study for Participants Previously Enrolled in Clinical Trials of Povorcitinib

NCT ID: NCT06855498

This clinical trial is a continuation study for people who have already participated in earlier studies involving a medication called povorcitinib, which is being tested for a skin condition known ...

Recruiting

Phase: PHASE3 Conditions: Hidradenitis Suppurativa (HS)

A Study to Assess the Long-term Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-3)

NCT ID: NCT06929273

The BALSAM-3 clinical trial is studying the long-term safety of a medication called KarXT for people with Bipolar-I Disorder who are experiencing manic episodes. This is an important study because ...

Not yet recruiting

Phase: PHASE3 Conditions: Bipolar Disorder Type I With Mania

A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer.

NCT ID: NCT06629779

This clinical trial is studying a new drug called PF-06821497 (also known as Mevrometostat) to see if it works better when combined with another medication called enzalutamide for men with metastat...

Recruiting

Phase: PHASE3 Conditions: Metastatic Castration-Resistant Prostate Cancer

A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder

NCT ID: NCT06775379

This clinical trial, called X-NOVA2, is studying a new medication called azetukalner to see how well it works for adults with Major Depressive Disorder (MDD). The trial is designed for adults aged ...

Recruiting

Phase: PHASE3 Conditions: Major Depressive Disorder

Study of PF-07220060 With Letrozole in Adults With HR-positive HER2-negative Breast Cancer Who Have Not Received Anticancer Treatment for Advanced/Metastatic Disease

NCT ID: NCT06760637

This clinical trial is studying a new treatment called PF-07220060, given alongside letrozole, for adults with a specific type of breast cancer known as HR-positive HER2-negative breast cancer. Thi...

Recruiting

Phase: PHASE3 Conditions: Breast Cancer

A Study to Determine if BHV-7000 is Effective and Safe in Adults With Idiopathic Generalized Epilepsy With Generalized Tonic-clonic Seizures

NCT ID: NCT06425159

This clinical trial is studying a new treatment called BHV-7000 to see if it is effective and safe for adults with idiopathic generalized epilepsy, specifically those who experience generalized ton...

Recruiting

Phase: PHASE2 Conditions: Generalized Epilepsy

A Study to Learn About the Study Medicine Called PF-07799544 in People With Advanced Solid Tumors

NCT ID: NCT05538130

This clinical trial is studying a new medicine called PF-07799544 to see how safe and effective it is for people with advanced solid tumors, such as melanoma, brain cancer, thyroid cancer, and lung...

Recruiting

Phase: PHASE1 Conditions: Colorectal Cancer, Melanoma +5 more

A Study to Learn About the Study Medicine PF-07934040 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Genetic Mutation.

NCT ID: NCT06447662

This clinical trial is studying a new medication called PF-07934040 to understand how safe it is and how well it works for people with advanced solid tumors that have a specific genetic change know...

Recruiting

Phase: PHASE1 Conditions: Carcinoma, Non-Small-Cell Lung, Colorectal Neoplasms +1 more

A Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced Solid Tumors With BRAF Alterations.

NCT ID: NCT05355701

This clinical trial is studying a new medicine called PF-07799933 to see how safe it is and how well it works for people with advanced solid tumors that have a specific gene change known as a "BRAF...

Recruiting

Phase: PHASE1 Conditions: Melanoma, Glioma +2 more

A Study to Learn About the Study Medicine PF-07985045 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Change in a Gene.

NCT ID: NCT06704724

This clinical trial is studying a new medicine called PF-07985045 to see how safe it is and how well it works in treating advanced solid tumors, which are lumps of abnormal cells in the body. The t...

Recruiting

Phase: PHASE1 Conditions: Carcinoma, Non-Small-Cell Lung, Colorectal Neoplasms +1 more

Study to Assess the Safety and Effectiveness of NMRA-335140-501

NCT ID: NCT06029439

This clinical trial, named NMRA-335140-501, is studying a new treatment called NMRA-335140 for people with Major Depressive Disorder (MDD). It is an extension of previous studies that looked at how...

Recruiting

Phase: PHASE3 Conditions: Major Depressive Disorder

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Clinical Trials in Rogers, Arkansas

50 Active Trials Found in Rogers

Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study

Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab

A Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-TNF Therapy

Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial

A Study of Barzolvolimab in Patients With Prurigo Nodularis

Efficacy and Safety Study of BHV-7000 Monotherapy in Major Depression

A Study of Sigvotatug Vedotin in Advanced Solid Tumors

Testing the Addition of the AKT Inhibitor, Ipatasertib, to Treatment With the Hormonal Agent Megestrol Acetate for Recurrent or Metastatic Endometrial Cancers

A Study to Evaluate the Long-Term Safety and Efficacy of Povorcitinib in Participants With Moderate to Severe Hidradenitis Suppurativa

Rollover Study for Participants Previously Enrolled in Clinical Trials of Povorcitinib

A Study to Assess the Long-term Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-3)

A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer.

A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder

Study of PF-07220060 With Letrozole in Adults With HR-positive HER2-negative Breast Cancer Who Have Not Received Anticancer Treatment for Advanced/Metastatic Disease

A Study to Determine if BHV-7000 is Effective and Safe in Adults With Idiopathic Generalized Epilepsy With Generalized Tonic-clonic Seizures

A Study to Learn About the Study Medicine Called PF-07799544 in People With Advanced Solid Tumors

A Study to Learn About the Study Medicine PF-07934040 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Genetic Mutation.

A Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced Solid Tumors With BRAF Alterations.

A Study to Learn About the Study Medicine PF-07985045 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Change in a Gene.

Study to Assess the Safety and Effectiveness of NMRA-335140-501