Clinical Trials for Autoimmune Diseases

Deciphering the Genetic Architecture of Autoimmune Diseases

NCT ID: NCT06948110

This clinical trial is focused on understanding the genetic factors that may lead to autoimmune diseases in people native to Peru. Autoimmune diseases occur when the body's immune system mistakenly...

The Role of Cytokines and Regulatory T Lymphocytes in Migraine Pathophysiology.

NCT ID: NCT06426316

This clinical trial is investigating the role of specific immune system cells and chemicals (called cytokines) in understanding migraines, a painful condition that affects many people, especially w...

CAR-T Cells Therapy for Patients With Autoimmune Diseases

NCT ID: NCT07052565

This clinical trial is studying a new treatment called CAR-T cell therapy for people with autoimmune diseases that have not responded well to other treatments. CAR-T therapy uses specially modified...

CAR-T Therapy for Refractory Autoimmune Diseases

NCT ID: NCT07059169

This clinical trial is exploring a new treatment called CAR-T therapy for people with autoimmune diseases that have not improved with standard treatments. Autoimmune diseases happen when the body’s...

Biomarkers in Autoimmune Diseases, Vasculitis and Auto Inflammatory Diseases

NCT ID: NCT05383339

This clinical trial is focused on understanding autoimmune diseases, which are conditions where the body's immune system mistakenly attacks its own tissues. The researchers aim to identify specific...

Antibiotic Prophylaxis in High-Risk Arthroplasty Patients

NCT ID: NCT04297592

A Phase 1 Study of ADI-001 in Autoimmune Disease

NCT ID: NCT06375993

This clinical trial is testing a new treatment called ADI-001 for patients with lupus nephritis, a kidney problem that can occur in people with lupus, an autoimmune disease. The goal of this study ...

Natural History of Type 1 Interferonopathies: Insights From a European Cohort

NCT ID: NCT07040774

This clinical trial is studying a group of rare genetic diseases called type I interferonopathies. These conditions cause the immune system to be overactive, leading to inflammation that mainly aff...

A Study of CAR-T Cells in Subjects With Autoimmune Diseases

NCT ID: NCT07040917

This clinical trial is studying a new treatment called CAR-T cell therapy for people with autoimmune diseases. Autoimmune diseases happen when the immune system, which normally protects the body, m...

Clonal Hematopoiesis of Immunological Significance

NCT ID: NCT05969821

This clinical trial, titled "Clonal Hematopoiesis of Immunological Significance," is focused on understanding certain immune system diseases and conditions, particularly those linked to a syndrome ...

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single- and Multiple-Ascending Doses and Food Effect of BGB-45035 in Healthy Participants and in Adults With Autoimmune Dermatological Diseases

NCT ID: NCT06342713

This clinical trial is studying a new drug called BGB-45035 to see how safe it is and how the body processes it. This is the first time BGB-45035 is being given to people, so researchers want to fi...

Network to Understand Reproductive Rheumatology Registry

NCT ID: NCT06940869

The NURTURE Registry is a clinical study aimed at understanding how rheumatic diseases, which are conditions that affect the immune system and joints, impact pregnancy and reproductive health. This...

Use of Acthar Gel Single-Dose Pre-Filled SelfJectTM Injector in Patients With Moderate-Severe Keratitis and Autoimmune Disease

NCT ID: NCT06964269

This clinical trial is studying the effects of Acthar Gel, a medication given by injection, on patients who have moderate to severe dry eye due to autoimmune diseases. The goal is to see if this tr...

Effect of Transcutaneous Electrical Acupoint Stimulation on Dysmenorrhea Among Autoimmune Disease Women

NCT ID: NCT06976151

This clinical trial is exploring a treatment called transcutaneous electrical acupoint stimulation to see if it can help reduce painful menstrual cramps (dysmenorrhea) in women who have autoimmune ...

A Clinical Study of CD19 CAR NK Cells for the Treatment of Relapsed/Refractory B-cell Related Autoimmune Diseases

NCT ID: NCT06318533

This clinical trial is exploring a new treatment option using a special type of immune cell called CD19 CAR NK cells (KN5501) for patients with certain autoimmune diseases that have not responded w...

Genotype-phenotype Characterization Study on Genetic Diseases With Immune and Neurological Dysfunctions

NCT ID: NCT06235580

This clinical trial, led by Prof. Yanick Crow and his team, is studying rare genetic diseases that affect both the immune system and the nervous system. These conditions can severely impact patient...

An Exploratory Clinical Study of CD19 CAR NK Cell Injection for the Treatment of Relapsed/Refractory Autoimmune Diseases

NCT ID: NCT06464679

This clinical trial is looking at a new treatment called CD19 CAR NK cell injection for people with autoimmune diseases that have not responded well to traditional therapies. The study aims to find...

X-linked Moesin Associated Immunodeficiency

NCT ID: NCT06278337

This clinical trial is studying a rare condition called X-linked Moesin Associated Immunodeficiency (X-MAID), which affects the immune system and can lead to frequent infections. The trial aims to ...

An Exploratory Clinical Study of SCAR02 Targeting BCMA and CD19 for the Treatment of Refractory Autoimmune Diseases

NCT ID: NCT06503224

This clinical trial is studying a new treatment called SCAR02, which targets specific proteins (BCMA and CD19) to help people with autoimmune diseases that have not responded to other treatments. T...

A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

NCT ID: NCT01351545

This clinical trial is looking at how to provide access to special cord blood units (CBUs) that have not yet been licensed for use. These CBUs are frozen and can be used to help treat various blood...