Clinical Trials for Bacterial Infections

Prospective Clinical Registry of Acute Treatment and Long-term Assessment of Children Meningitis

NCT ID: NCT07062445

This clinical trial is studying how children with meningitis—a serious infection of the lining around the brain and spinal cord—are treated and how they recover both during their hospital stay and ...

Dose-finding, Pharmacokinetics, and Safety of VABOMERE in Pediatric Subjects With Bacterial Infections

NCT ID: NCT02687906

This clinical trial is testing a medication called Vabomere (meropenem-vaborbactam) to find the right dose and check its safety in children and teenagers under 18 years old who have serious bacteri...

The AcCREDiT 2 Study

NCT ID: NCT07029672

The AcCREDiT 2 study is looking at people who come to the hospital with breathing problems caused by lung infections, like pneumonia, or flare-ups of long-term lung conditions such as chronic obstr...

Monotherapy vs Combination Therapy for Bone Infections Caused by Pseudomonas Aeruginosa

NCT ID: NCT07056881

This clinical trial is studying the best way to treat bone infections caused by a specific type of bacteria called Pseudomonas aeruginosa. The researchers want to find out if using just one antibio...

A Follow-up Trial of GBS-NN/NN2 Vaccine in Healthy Pregnant Women

NCT ID: NCT06592586

This clinical trial is studying a vaccine called GBS-NN/NN2, which is designed to help protect against infections caused by a type of bacteria known as Group B Streptococcus (GBS). This study will ...

A Study to Evaluate the Immunogenicity and Safety of 13-valent Pneumococcal Conjugate Vaccine (PCV13i) in Healthy Infants Aged 2 Months (Minimum 6 Weeks)

NCT ID: NCT07017777

This clinical trial is studying a new vaccine called the 13-valent Pneumococcal Conjugate Vaccine (PCV13i) to see how well it works and how safe it is for healthy infants aged 2 months. The trial w...

Application of Bacterial DNA Quantitative Detection in Diagnosis of SBP in Cirrhosis: A Multi Center Diagnostic Experiment

NCT ID: NCT06995846

Biodistribution and Pathophysiology Study of 11C-para-aminobenzoic Acid

NCT ID: NCT05611905

This clinical trial is studying a new imaging technique using a special substance called 11C-para-aminobenzoic Acid (11C-PABA) to help doctors see infections in the body. The goal is to find out if...

Diagnostic Evaluation Study of the BactInsight Blood Culture System in West-Africa

NCT ID: NCT05722184

This clinical trial is studying a new blood culture system called BactInsight, which aims to improve the diagnosis of bacterial infections in people living in West Africa. In many areas, it's hard ...

A Study to Evaluate Efficacy, Safety, and PK of XEMBIFY®+Standard Medical Treatment (SMT) Compared to Placebo+SMT to Prevent Infections in Participants With HGG and Recurrent or Severe Infections Associated With B-cell Chronic Lymphocytic Leukemia, Multiple Myeloma, and Non-Hodgkin Lymphoma

NCT ID: NCT05645107

This clinical trial is studying a treatment called XEMBIFY® to see if it can help prevent serious bacterial infections in patients with certain types of blood cancers, including B-cell Chronic Lymp...

Integrated Clinical Decision Support for Empiric Antibiotic Selection in Sepsis

NCT ID: NCT06103500

This clinical trial is looking at how to improve the choice of antibiotics for patients with sepsis, a serious condition caused by infections. As antibiotic resistance becomes more common, it’s ess...

P1, DDI & MAD PK and Safety Study of Xeruborbactam Oral Prodrug in Combo With Ceftibuten in Healthy Participants

NCT ID: NCT06079775

This clinical trial is studying a new medication called Xeruborbactam, taken as an oral prodrug, in combination with another antibiotic called Ceftibuten. The goal is to see how well these medicati...

A DDI Study to Investigate PK and Safety of Cefiderocol in Combination With Xeruborbactam in Healthy Adult Participants

NCT ID: NCT06547554

This clinical trial is studying the safety and effectiveness of two medications, cefiderocol and xeruborbactam, when taken together. Both of these drugs are designed to treat bacterial infections, ...

[18F]Fluoropropyl-Trimethoprim ([18F]F-TMP) PET/CT Imaging to Evaluate Biodistribution and Kinetics in Human Subjects

NCT ID: NCT04263792

This clinical trial is studying a special imaging drug called [18F]F-TMP, which is injected into the body to help doctors see areas where bacterial infections are active. The imaging test used in t...

LázBarát™ (FeverFriend™) Projekt: Attitude Toward Fever and Its Change in the Healthcare System

NCT ID: NCT04633603

Healthrelated Quality of Life and Experiences of a Heart Rehabilitation Programme After Care for Infective Endocarditis.

NCT ID: NCT06704048

This clinical trial is studying whether joining a heart rehabilitation program can help improve the health and quality of life for patients who have had infective endocarditis, a serious heart infe...

International Surveillance of Antimicrobial Resistance in Cirrhosis-Related Infections

NCT ID: NCT06634940

This clinical trial is focused on understanding how bacteria behave in patients with cirrhosis who develop bacterial infections. Cirrhosis is a serious liver condition that makes patients more vuln...

A Cluster Randomized Controlled Trial to Compare the Rate of Antibiotic Infusion

NCT ID: NCT06620341

This clinical trial is looking at how to reduce the use of intravenous antibiotics for patients with bacterial infections of the upper respiratory tract, like colds or sore throats, who come to the...

Fosfomycin I.v. for Treatment of Severely Infected Patients

NCT ID: NCT02979951

This clinical trial is studying the use of a medication called fosfomycin, given through an IV, to treat patients with severe bacterial infections. These infections can include serious conditions l...

Trial Comparing Conventional Antibiotic Strategies Versus Regimens Guided by Epidemiological Surveillance in Infected Patients With Cirrhosis (SURVIC_STUDY)

NCT ID: NCT05783661

The SURVIC_STUDY is a clinical trial designed to compare two different approaches to treating bacterial infections in patients with a serious liver condition called cirrhosis. The study aims to fin...