Clinical Trials for Colorectal Cancer

Find clinical trials for colorectal cancer. Discover research opportunities and treatment options in your area.

623 Active Trials Found

Showing 623 trials on this page

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A Study to Learn About the Study Medicine Called PF-07799544 in People With Advanced Solid Tumors

NCT ID: NCT05538130

This clinical trial is studying a new medicine called PF-07799544 to see how safe and effective it is for people with advanced solid tumors, such as melanoma, brain cancer, thyroid cancer, and lung...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, Detroit, Michigan, United States +53 more

A Study to Assess Adverse Events and Change in Disease Activity in Adult Participants Receiving Intravenously Infused Telisotuzumab Adizutecan Alone or With Standard of Care in Participants With Post Adjuvant Circulating Tumor DNA Positive Colorectal Cancer and No Radiographic Evidence of Disease

NCT ID: NCT07023289

This clinical trial is studying a new treatment called telisotuzumab adizutecan for adults with colorectal cancer (CRC) who have no visible signs of the disease but have detectable cancer DNA in th...

Recruiting

Phase: PHASE2 Type: interventional Locations: Austin, Texas, United States, Taichung, , Taiwan +2 more

Ultrasound for the Detection of Oxaliplatin-Induced Peripheral Neuropathy

NCT ID: NCT03958747

This clinical trial is exploring how effective ultrasound is in detecting a condition called peripheral neuropathy, which can occur in patients with gastrointestinal cancers, particularly colorecta...

Recruiting

Phase: NA Type: interventional Locations: Winston Salem, North Carolina, United States

A Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-6036 Alone or in Combination in Participants With Advanced or Metastatic Solid Tumors With a KRAS G12C Mutation

NCT ID: NCT04449874

This clinical trial is investigating a new treatment called GDC-6036 for patients with advanced or metastatic solid tumors that have a specific mutation known as KRAS G12C. The trial aims to unders...

Recruiting

Phase: PHASE1 Type: interventional Locations: New York, New York, United States, Duarte, California, United States +116 more

Phase I Study of [177Lu]Lu-NNS309 in Patients With Pancreatic, Lung, Breast and Colorectal Cancers

NCT ID: NCT06562192

This clinical trial is studying a new treatment called [177Lu]Lu-NNS309 for patients with advanced stages of certain types of cancer, including pancreatic, lung, breast, and colorectal cancers. The...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, Stanford, California, United States +12 more

FOG-001 in Locally Advanced or Metastatic Solid Tumors

NCT ID: NCT05919264

This clinical trial, called FOG-001, is investigating a new treatment for people with advanced or metastatic solid tumors, which are types of cancer that have spread beyond their original site. The...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, New York, New York, United States +9 more

Collection of Information to Better Understand Young Onset Colorectal Cancer

NCT ID: NCT04489238

This clinical trial is focused on understanding young onset colorectal cancer, which refers to cases diagnosed in individuals under the age of 50. Researchers are creating a database to collect imp...

Recruiting

Type: observational Locations: New York, New York, United States, Montvale, New Jersey, United States +6 more

Encorafenib Plus Cetuximab in a Neoadjuvant Setting in Patients With BRAF Mutation Localised Colon or Upper Rectum Cancer

NCT ID: NCT05706779

This clinical trial is looking at a new treatment approach for patients with localized colorectal cancer that has a specific mutation called BRAF V600E. The study is testing a combination of two me...

Recruiting

Phase: PHASE2 Type: interventional Locations: Paris, , France

The Effects of Clostridium Butyricum on Adverse Events During Adjuvant Chemotherapy for Colorectal Cancer

NCT ID: NCT07152886

This clinical trial is studying whether a helpful type of bacteria called Clostridium butyricum can reduce side effects in people receiving extra chemotherapy treatment after surgery for colorectal...

Not yet recruiting

Phase: PHASE4 Type: interventional

Botensilimab + Balstilimab vs Best Supportive Care as Therapy in Chemo-refractory, Unresectable, Colorectal Adenocarcinoma

NCT ID: NCT07152821

This clinical trial is studying whether a new treatment using two immunotherapy drugs, botensilimab and balstilimab, can help people with colorectal cancer that cannot be removed by surgery and has...

Not yet recruiting

Phase: PHASE3 Type: interventional

LEgal Guidance and AdvocaCY for CAREgivers (LEGACY CARE): A Pilot Clinical Trial for Caregivers of Persons With Colorectal Cancer

NCT ID: NCT07153016

This clinical trial, called LEGACY CARE, is looking at how offering free legal help early on can support people who are caring for loved ones with colorectal cancer. Caregivers often face a lot of ...

Not yet recruiting

Phase: NA Type: interventional

Phase II RCT of LCRT vs SCRT + CAPOX/PD-1i/COX-2i in MSS Locally Advanced Rectal Cancer

NCT ID: NCT07154316

This clinical trial is studying two different treatment approaches for people with a type of rectal cancer called microsatellite stable (MSS) locally advanced rectal cancer. The goal is to see whic...

Recruiting

Phase: PHASE2 Type: interventional

A Retrospective Protocol Empowering Precision Research in Colorectal Cancer (ALFAOMEGA-RETRÒ)

NCT ID: NCT05101382

The ALFAOMEGA-RETRÒ trial is looking to gather important information about colorectal cancer, a type of cancer that affects the colon or rectum. Researchers will collect past medical records, imagi...

Recruiting

Type: observational Locations: Pisa, , Italy, Barcelona, , Spain +11 more

ALFAOMEGA Master Observational Trial

NCT ID: NCT04120935

The ALFAOMEGA Master Observational Trial is a study focused on understanding colorectal cancer (CRC) better. Researchers are looking at how cancer cells and the body’s healthy cells interact over t...

Recruiting

Type: observational Locations: Pisa, , Italy, Torino, , Italy +17 more

Autologous T-cells Genetically Engineered to Express Receptors Reactive Against KRAS Mutations in Conjunction With a Vaccine Directed Against These Antigens in Participants With Metastatic Cancer

NCT ID: NCT06253520

This clinical trial is exploring a new treatment for adults with advanced cancers that have spread, such as colorectal, breast, lung, gastrointestinal, ovarian, and genitourinary cancers. The goal ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Bethesda, Maryland, United States

BOLD-100 in Combination With FOLFOX for the Treatment of Advanced Solid Tumours

NCT ID: NCT04421820

The BOLD-100 trial is studying a new treatment for patients with advanced solid tumors, specifically colorectal, pancreatic, gastric cancers, and cholangiocarcinoma (bile duct cancer). This trial c...

Recruiting

Phase: PHASE1 Type: interventional Locations: Tampa, Florida, United States, Montreal, Quebec, Canada +18 more

Evaluation for NCI Surgery Branch Clinical Research Protocols

NCT ID: NCT00001823

This clinical trial, led by the National Cancer Institute Surgery Branch (NCI-SB), is exploring new experimental treatments for various types of cancer, including synovial cell cancer, melanoma, co...

Recruiting

Type: observational Locations: Bethesda, Maryland, United States

A Phase 2 Trial of Fruquintinib and Tislelizumab in ctDNA-defined Minimal Residual Disease in Colorectal Cancer After Completion of Adjuvant Chemotherapy

NCT ID: NCT07136077

This clinical trial is testing whether a combination of two medicines, fruquintinib and tislelizumab, can help control colorectal cancer in patients who have finished their initial chemotherapy but...

Not yet recruiting

Phase: PHASE2 Type: interventional Locations: Houston, Texas, United States

SIBYL: obServation of Therapy Response With lIquid BiopsY evaLuation

NCT ID: NCT05935384

The SIBYL trial is studying how well a new test called Guardant360 can help doctors understand how patients with advanced solid tumors, like certain types of lung, colorectal, and breast cancer, ar...

Recruiting

Type: observational Locations: Skokie, Illinois, United States

Immunotherapies in Combination With Stereotactic Body Radiation Radiotherapy in Microsatellite Stable (MSS) Metastatic Colorectal Cancer (mCRC)

NCT ID: NCT06603818

This clinical trial is exploring a new treatment approach for patients with microsatellite stable metastatic colorectal cancer (mCRC), which is a type of cancer that has spread beyond the colon and...

Recruiting

Phase: PHASE2 Type: interventional Locations: Bethesda, Maryland, United States

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