Clinical Trials for Colorectal Cancer

Find clinical trials for colorectal cancer. Discover research opportunities and treatment options in your area.

632 Active Trials Found

Showing 632 trials on this page

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A Trial to Evaluate the Safety and Activity of Fruquintinib in Minority Populations With Advanced, Previously Treated Colorectal Cancer

NCT ID: NCT06562543

This clinical trial is investigating the safety and effectiveness of a medication called fruquintinib in minority groups, specifically Black or African American and Hispanic or Latino adults, who h...

Recruiting

Phase: PHASE4 Type: interventional Locations: Los Angeles, California, United States, Houston, Texas, United States +48 more

A Study to Test Different Doses of BI 765049 Alone and in Combination With Ezabenlimab in Asian People With Advanced Cancer (Solid Tumours) Positive for B7-H6

NCT ID: NCT06091930

This clinical trial is investigating a new treatment approach for adults in Asia who have advanced solid tumors, such as gastrointestinal, lung, pancreatic, colorectal, head and neck, or liver canc...

Recruiting

Phase: PHASE1 Type: interventional Locations: Taipei, , Taiwan, Shanghai, , China +6 more

A Phase II Study of Adjuvant Immunotherapy Targeting KRAS G12D, KRAS G12V, or TP53 R175H for Participants With Advanced Gastrointestinal Malignancies

NCT ID: NCT06690281

This clinical trial is studying a new type of treatment called T-cell therapy for patients with advanced gastrointestinal (GI) cancers, such as pancreatic, liver, and colorectal cancers. The goal i...

Recruiting

Phase: PHASE2 Type: interventional Locations: Bethesda, Maryland, United States

Immunotherapies in Combination With Stereotactic Body Radiation Radiotherapy in Microsatellite Stable (MSS) Metastatic Colorectal Cancer (mCRC)

NCT ID: NCT06603818

This clinical trial is exploring a new treatment approach for patients with microsatellite stable metastatic colorectal cancer (mCRC), which is a type of cancer that has spread beyond the colon and...

Not yet recruiting

Phase: PHASE2 Type: interventional Locations: Bethesda, Maryland, United States

A Phase II Study Evaluating an Organ Preservation Strategy Using Immune Checkpoint Blockade for Participants With Primary Colorectal or Gastroesophageal Cancer

NCT ID: NCT06410534

This clinical trial is studying the effects of two approved medications, nivolumab and ipilimumab, to see if they can help people with colorectal or gastroesophageal cancer avoid or delay major sur...

Recruiting

Phase: PHASE2 Type: interventional Locations: Bethesda, Maryland, United States

Study in mCRC Patients RAS/BRAF wt Tissue and RAS Mutated LIquid BIopsy to Compare FOLFIRI Plus CetuxiMAb or BevacizumaB

NCT ID: NCT04776655

This clinical trial is studying a new way to treat a type of advanced colorectal cancer (cancer of the colon or rectum that has spread to other parts of the body) in patients whose cancer has speci...

Recruiting

Phase: PHASE3 Type: interventional Locations: Reggio Emilia, , Italy, Coppito, L'aquila, Italy +2 more

A Study to Assess IPN01194 When Administered Alone in Adults With Advanced Solid Tumours

NCT ID: NCT06305247

This clinical trial is studying a new medication called IPN01194 to see how safe and effective it is for adults with advanced solid tumors. These tumors can come from various cancers, including mel...

Recruiting

Phase: PHASE1 Type: interventional Locations: Fairfax, Virginia, United States, Nashville, Tennessee, United States +10 more

Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

NCT ID: NCT04981119

This clinical trial is exploring how often certain solid tumors, like colorectal cancer and lung cancer, lose a specific gene marker called Human Leukocyte Antigen (HLA) and how this loss might aff...

Recruiting

Type: observational Locations: Palo Alto, California, United States, Rochester, Minnesota, United States +12 more

A Study to Evaluate the Safety, Pharmacokinetics, and Activity of RO7502175 as a Single Agent and in Combination With Checkpoint Inhibitor in Participants With Locally Advanced or Metastatic Solid Tumors

NCT ID: NCT05581004

This clinical trial is testing a new treatment called RO7502175, both on its own and in combination with another medication called atezolizumab. The study is designed for adults who have locally ad...

Recruiting

Phase: PHASE1 Type: interventional Locations: Detroit, Michigan, United States, Atlanta, Georgia, United States +41 more

In Vivo Lung Perfusion (IVLP) for Colorectal Cancer Metastatic to Lung

NCT ID: NCT05611034

This clinical trial is studying a new method called In Vivo Lung Perfusion (IVLP) to deliver chemotherapy directly into the lungs of patients with colorectal cancer that has spread to the lungs. Th...

Recruiting

Phase: PHASE1 Type: interventional Locations: Toronto, Ontario, Canada

A Study of the Pan-KRAS Inhibitor LY4066434 in Participants With KRAS Mutant Solid Tumors

NCT ID: NCT06607185

This clinical trial is studying a new medication called LY4066434, which is designed to target specific mutations in a gene called KRAS found in certain types of cancer. The trial focuses on patien...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, Durham, North Carolina, United States +73 more

SMARTER: Using Blood Samples to iMprove FIT-bAsed coloRecTal cancEr scReening

NCT ID: NCT06714318

The SMARTER trial is looking into a new way to improve colorectal cancer screening by using blood tests. Currently, people aged 50 to 74 in Denmark are invited to take a stool test every two years ...

Recruiting

Type: observational Locations: Vejle, , Denmark, Aabenraa, , Denmark

MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors

NCT ID: NCT06586515

This clinical trial is studying a new treatment called LY3962673 for patients with certain types of advanced cancer, specifically those with a KRAS G12D mutation. The main goal of the study is to e...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, Durham, North Carolina, United States +91 more

Developing Risk Prediction Model and Testing the Effect of Dual Task Walking on Improving Cognitive Function in Patients With Colorectal Cancer

NCT ID: NCT04490733

This clinical trial is studying how colorectal cancer affects thinking and memory skills at different stages of the disease. The researchers want to understand how cancer-related thinking problems ...

Recruiting

Phase: NA Type: interventional Locations: Taipei, , Taiwan

The PharmFIT Study

NCT ID: NCT06656936

The PharmFIT Study is a clinical trial designed to find out if a new approach, called Pharmacy-based FIT (PharmFIT), can help increase the number of people getting screened for colorectal cancer. C...

Not yet recruiting

Phase: NA Type: interventional

mPATH-Cloud for Colorectal Cancer Screening

NCT ID: NCT06441487

The mPATH-Cloud for Colorectal Cancer Screening trial is studying a new way to encourage people to get screened for colorectal cancer (CRC). This study aims to see if using a mobile health tool cal...

Not yet recruiting

Phase: NA Type: interventional Locations: Winston Salem, North Carolina, United States, Chapel Hill, North Carolina, United States

An Evaluation of NGM120 in a Randomized, Double-blind, Placebo-controlled Study in Participants With Colorectal Cancer Who Have Cancer Cachexia.

NCT ID: NCT07033026

This clinical trial is testing a medicine called NGM120 to see if it can help people with colorectal cancer who are also experiencing cancer cachexia. Cancer cachexia is a condition where someone l...

Not yet recruiting

Phase: PHASE2 Type: interventional

A Phase 1/2a Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors

NCT ID: NCT07020221

This clinical trial is studying a new treatment called VS-7375 for patients with certain types of advanced solid tumors that have a specific genetic change known as the KRAS G12D mutation. The goal...

Recruiting

Phase: PHASE1 Type: interventional Locations: Seattle, Washington, United States, Houston, Texas, United States +1 more

Early Detection of Advanced Adenomas and Colorectal Cancer

NCT ID: NCT06342440

This clinical trial is looking to create a new blood test that can help find colorectal adenomas (precancerous growths) and colorectal cancer early. The goal is to make this test highly sensitive a...

Recruiting

Type: observational Locations: San Diego, California, United States, Milan, , Italy +4 more

A Study of HFB200603 as a Single Agent and in Combination With Tislelizumab in Adult Patients With Advanced Solid Tumors

NCT ID: NCT05789069

This clinical trial is studying a new treatment called HFB200603, both on its own and in combination with another medication called tislelizumab, for adult patients with advanced cancers such as re...

Recruiting

Phase: PHASE1 Type: interventional Locations: Philadelphia, Pennsylvania, United States, Valencia, , Spain +9 more

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