Clinical Trials for Critical Illness

Using sEMG of the Diaphragm to Assess Readiness for Extubation

NCT ID: NCT07110129

This clinical trial is studying a new way to help doctors decide when a patient in the Intensive Care Unit (ICU) is ready to have their breathing tube removed. When someone is very sick, they often...

Curriculum for Airway Skills in Critically Ill Adults: a Delphi Evaluation

NCT ID: NCT06689748

Microvascular Monitoring in Circulatory Shock and Sepsis (MiMICSS)

NCT ID: NCT05985525

The MiMICSS trial is studying a new way to monitor how well the tiny blood vessels are working in critically ill patients, specifically those who are experiencing severe conditions like sepsis and ...

Innate Immune Response Monitoring Via Monocyte HLA-DR in Severe Intra-abdominal Infections at Risk of Fungal Infection

NCT ID: NCT07130799

This clinical trial is studying a serious type of fungal infection called intra-abdominal candidiasis (IAC), which can happen in patients who are very sick with infections inside the belly, especia...

Clinical Effectiveness of the "PICU Up!" Multifaceted Early Mobility Intervention for Critically Ill Children

NCT ID: NCT04989790

This clinical trial is studying a new approach called the "PICU Up!" intervention, which aims to help critically ill children recover more effectively while they are in the Pediatric Intensive Care...

ICU Fluid Utilization Survey in Southeast Asia

NCT ID: NCT06034990

The ICU Fluid Utilization Survey in Southeast Asia is a clinical trial aimed at understanding how different types of fluids are used to treat critically ill patients in intensive care units (ICUs)....

COPM-Based Goal Setting Strategies in the PICU

NCT ID: NCT07128446

This clinical trial is exploring a new way to set personalized care goals for children in the Pediatric Intensive Care Unit (PICU) using a tool called the Canadian Occupational Performance Measure ...

Bone Loss Prevention With Zoledronic Acid or Denosumab in Critically Ill Adults

NCT ID: NCT04608630

The Bone Zone trial is studying how two medications, denosumab and zoledronic acid, can help prevent bone loss in critically ill adults. This trial is specifically looking at women aged 50 and olde...

Asia Pediatric Intensive Care Epidemiology and Outcomes Study

NCT ID: NCT06481644

The Asia Pediatric Intensive Care Epidemiology and Outcomes Study is a research project aimed at improving the care of children who are critically ill and need intensive medical support. The study ...

Optimised Nutritional Therapy and Early Physiotherapy in Long Term ICU Patients (NutriPhyT Trial)

NCT ID: NCT05865314

**Summary of the NutriPhyT Trial** The NutriPhyT Trial is a study looking at whether better nutrition and early physical activity can help patients who have been in the intensive care unit (ICU) f...

Post-Intensive Care Transitional Care, Rehabilitation, and Family-Support

NCT ID: NCT06501365

This clinical trial is studying a program called Post-Intensive Care Transitions, Rehabilitation, and Family Support (PIC-TRFS) to see if it can help patients and their families after a serious ill...

VoiceLove: An App-Based COMMunication Tool Designed to Address DeliriUm and Improve Family ENgagement and PatIent/Family SatisfaCtion in CriticAlly Ill PaTiEnts (COMMUNICATE)

NCT ID: NCT06923462

The VoiceLove trial is studying a new phone app designed to help families and patients communicate better while in the intensive care unit (ICU). The app allows families to share information secure...

The Intensive Care Platform Trial

NCT ID: NCT06667999

The Intensive Care Platform Trial (INCEPT) is a research study designed to improve the treatment of critically ill patients in intensive care units (ICUs). The trial aims to evaluate the effectiven...

Communication With Mechanically Ventilated Intensive Care Patients

NCT ID: NCT06977555

The Effect of the Timing of Supplemental Parenteral Nutrition on the Prognosis of Critically Ill Patients (T-SPN)

NCT ID: NCT07085455

This clinical trial is studying whether giving extra nutrition through an IV (called supplemental parenteral nutrition or SPN) earlier during a stay in the intensive care unit (ICU) helps criticall...

Surface Electrical Myography, Oxygen Consumption, Effort, and Weaning in the Mechanically Ventilated Patient in the Intensive Care Unit

NCT ID: NCT07109570

This study is looking at patients in the Intensive Care Unit (ICU) who are on mechanical ventilators—machines that help them breathe. The researchers want to understand how much effort these patien...

Near-Infrared Light Devices Versus Landmark Approach for Peripheral Venous Access in Intensive Care Unit

NCT ID: NCT06234293

This clinical trial is studying two different methods for placing a peripheral intravenous catheter (PIVC) in critically ill patients who have already had a central venous catheter (CVC) removed. T...

PK, Safety and Preliminary Efficacy Study of Montelukast in Critically Ill Infants With Developing Bronchopulmonary Dysplasia

NCT ID: NCT07101640

This clinical trial is studying the safety and how the medicine montelukast behaves in the bodies of very premature infants who are critically ill and at risk of developing a lung condition called ...

Lactoferrin Use in ICU Patients

NCT ID: NCT05936528

This clinical trial is studying the effects of lactoferrin, a natural substance known for its health benefits, on patients in the Intensive Care Unit (ICU). Researchers want to see if lactoferrin c...

Effect of Ventilation Mode in the Pupillary Light Reflex: A Crossover Study

NCT ID: NCT07082569

This clinical trial is studying how different types of mechanical breathing support, called ventilation modes, might affect the way the pupils in the eyes respond to light in critically ill patient...