Clinical Trials for Critical Limb Ischemia

Find clinical trials for critical limb ischemia. Discover research opportunities and treatment options in your area.

29 Active Trials Found

Showing 29 trials on this page

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Serrantor OCT Study

NCT ID: NCT06434194

The Serrantor OCT Study is a clinical trial designed to explore a new treatment called serration angioplasty for patients suffering from Critical Limb Ischemia (CLI), a serious condition that reduc...

Recruiting

Phase: NA Type: interventional Locations: New York, New York, United States, New York, New York, United States

Use of Thermal Imaging Camera to Assess Perfusion Before and After Vascular Intervention

NCT ID: NCT06544135

This clinical trial is studying how using a special camera, called a thermal imaging camera, can help doctors understand changes in temperature in the legs before and after a procedure to improve b...

Recruiting

Type: observational Locations: Parma, Ohio, United States, Cleveland, Ohio, United States +1 more

Effect of Environmental Temperature on Vascular Ultrasound Vein Scan Measurements

NCT ID: NCT06191237

This clinical trial is looking at how different room temperatures might affect the measurements taken during vascular ultrasound scans of veins in patients with critical limb ischemia, a condition ...

Not yet recruiting

Type: observational

miRNAs in Critical Limb Ischemia (miRNACLI)

NCT ID: NCT06066268

The miRNAs in Critical Limb Ischemia (miRNACLI) trial is studying a serious condition called critical limb ischemia (CLI), which causes severe pain and can lead to amputations in the legs due to po...

Recruiting

Type: observational Locations: San Donato Milanese, Milan, Italy

TP03HN106 in Patients With Critical Limb Ischemia

NCT ID: NCT06482892

This clinical trial, named TP03HN106, is studying a potential new treatment for patients suffering from Critical Limb Ischemia (CLI), a serious condition where blood flow to the legs is severely re...

Recruiting

Phase: PHASE2 Type: interventional Locations: Suzhou, Jiangsu, China

MOTIV BTK Randomized Controlled Trial

NCT ID: NCT05406622

The MOTIV BTK trial is studying a new treatment for people with Critical Limb Ischemia (CLI), a serious condition where blood flow to the legs is severely restricted, often causing pain and difficu...

Recruiting

Phase: NA Type: interventional Locations: Leipzig, , Germany, Saint Helena, California, United States +2 more

FAZA PET/MRI in CLI Patients Pre and Post Revascularization

NCT ID: NCT04054609

This clinical trial is studying a new imaging technique called FAZA PET/MRI to help better understand a condition known as Critical Limb Ischemia (CLI). CLI is a serious problem where blood flow to...

Recruiting

Phase: NA Type: interventional Locations: Toronto, Ontario, Canada

Additional Hyperbaric Oxygen After Lower Extremity Amputation

NCT ID: NCT03594344

This clinical trial is studying the effects of hyperbaric oxygen therapy on patients who have had a lower limb amputation due to complications related to diabetes, such as chronic wounds or infecti...

Recruiting

Phase: NA Type: interventional Locations: Oslo, , Norway, Oslo, , Norway

Temsirolimus Adventitial Delivery to Improve ANGioplasty And/or Atherectomy Revascularization Outcomes Below the Knee

NCT ID: NCT04433572

This clinical trial is studying a treatment called Temsirolimus, which is injected near blood vessels, to see if it helps improve outcomes for patients with severe leg circulation problems, specifi...

Not yet recruiting

Phase: PHASE3 Type: interventional

CRUSH PAD: Real-world Outcomes Following Use of Shockwave Intravascular Lithotripsy (IVL) Technology in Calcified Common Femoral Lesions

NCT ID: NCT05145478

The CRUSH PAD clinical trial is studying the use of a new treatment called Shockwave Intravascular Lithotripsy (IVL) for patients with hardening of the arteries in the thigh area, specifically in t...

Recruiting

Type: observational Locations: New Haven, Connecticut, United States

Safety, Tolerability, and Biodistribution of [89Zr]Zr-DFO-APAC in Subjects With PAOD/CLI and Healthy Volunteers (Acronyms: 89Zr = Zirconium-89, DFO = Desferrioxamine, APAC = AntiPlatelet AntiCoagulant, PET/CT = Positron Emission Tomography/Computed Tomography)

NCT ID: NCT06204237

This clinical trial is studying a new treatment called [89Zr]Zr-DFO-APAC to learn how safe it is and how it spreads in the body. It involves patients with a condition known as Peripheral Arterial O...

Recruiting

Phase: EARLY_PHASE1 Type: interventional Locations: Groningen, , Netherlands

Tolerance Study of Allogeneic of Adipose Tissue Derived Mesenchymal Stroma/Stem Cells (AdMSC) Transplantation in Patients With Critical Limb Ischemia.

NCT ID: NCT06795620

This clinical trial is investigating a new treatment for patients with Critical Limb Ischemia (CLI), a serious condition where blood flow to the legs is severely restricted, causing pain and potent...

Not yet recruiting

Phase: PHASE1 Type: interventional Locations: Toulouse, , France

Nutrition in Patient With Critical Limb Ischemia

NCT ID: NCT03529019

This clinical trial is looking at how nutritional supplements can help patients with Critical Limb Ischemia (CLI), a serious condition that affects blood flow to the legs and can lead to pain and e...

Recruiting

Phase: EARLY_PHASE1 Type: interventional Locations: Boston, Massachusetts, United States

Acceleration Time Assessment for Prediction of Critical Limb Ischemia

NCT ID: NCT06296576

This clinical trial is studying a new and easy way to diagnose Critical Limb Ischemia (CLI), a serious condition where blood flow to the legs is severely reduced, leading to pain or wounds. The goa...

Recruiting

Type: observational Locations: Cholet, , France, Poitiers, , France +1 more

Trial to Assess Chelation Therapy in Critical Limb Ischemia

NCT ID: NCT03982693

The TACT3a trial is a research study that aims to test a new treatment using chelation therapy, which is designed to remove harmful metals from the body. This study specifically looks at how effect...

Recruiting

Phase: PHASE3 Type: interventional Locations: Miami Beach, Florida, United States

PROMISE III: Percutaneous Deep Vein Arterialization for the Treatment of Late-Stage Chronic Limb-Threatening Ischemia

NCT ID: NCT05313165

The PROMISE III trial is looking at a new treatment option for patients with severe leg circulation problems known as chronic limb-threatening ischemia. This condition can cause painful sores or ev...

Recruiting

Phase: NA Type: interventional Locations: Boston, Massachusetts, United States, Philadelphia, Pennsylvania, United States +29 more

Drug Eluting Temporary Spur Stent System vs Percutaneous Balloon Angioplasty for the Treatment of Critical Limb Ischemia

NCT ID: NCT06122974

This clinical trial is studying a new treatment called the Drug Eluting Temporary Spur Stent System to see how safe and effective it is compared to a common procedure called balloon angioplasty for...

Not yet recruiting

Phase: NA Type: interventional

Evaluation of the MAGNITUDE® Bioresorbable Drug-Eluting Scaffold in the Treatment of Patients With Below the Knee Disease in Australia

NCT ID: NCT06075940

This clinical trial is studying a new treatment option called the MAGNITUDE Bioresorbable Drug-Eluting Scaffold (BRS) for patients suffering from serious circulation problems in their legs, specifi...

Recruiting

Phase: NA Type: interventional Locations: Randwick, New South Wales, Australia

Safety and Preliminary Efficacy of Allogeneic Endothelial Progenitor Cells (EPCs) in Patients With Critical Limb Ischemia

NCT ID: NCT06359912

This clinical trial is exploring the safety and early effectiveness of using a special type of cells called allogeneic Endothelial Progenitor Cells (EPCs) to treat patients suffering from critical ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Beijing, Beijing, China

Evaluation of Tissue Perfusion in Peripheral Arterial Disease (EVTI-PAD)

NCT ID: NCT05570019

The EVTI-PAD trial is studying how blood flow to the legs is affected in patients with a condition called Peripheral Arterial Disease (PAD), which can cause severe pain and problems with circulatio...

Recruiting

Type: observational Locations: Innsbruck, Tyrol, Austria

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