A Phase II/III Trial of Nivolumab, Ipilimumab, and GM-CSF in Patients With Advanced Melanoma

NCT ID: NCT02339571

This clinical trial is investigating the effectiveness and side effects of two immunotherapy drugs, nivolumab and ipilimumab, either alone or combined with another drug called sargramostim, for pat...

Recruiting

Phase: PHASE2 Conditions: Stage IV Cutaneous Melanoma AJCC v6 and v7, Stage III Cutaneous Melanoma AJCC v7

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

NCT ID: NCT03866382

This clinical trial is investigating how well three medications—cabozantinib, nivolumab, and ipilimumab—work together to treat patients with rare genitourinary tumors that have spread to other part...

Recruiting

Phase: PHASE2 Conditions: Stage IVB Prostate Cancer AJCC v8, Stage IV Renal Cell Cancer AJCC v8 +43 more

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-Small Cell Lung Cancer, ALCHEMIST Trial

NCT ID: NCT04267848

The ALCHEMIST trial is a clinical study looking at whether adding a drug called pembrolizumab, which is a type of immunotherapy, to standard chemotherapy can improve treatment outcomes for patients...

Recruiting

Phase: PHASE3 Conditions: Stage IIIB Lung Cancer AJCC v8, Stage IIIA Lung Cancer AJCC v8 +4 more

National Cancer Institute "Cancer Moonshot Biobank"

NCT ID: NCT04314401

The "Cancer Moonshot Biobank" is a clinical trial that aims to gather blood and tissue samples from patients diagnosed with various types of cancer, including advanced stages of breast cancer, lung...

Recruiting

Conditions: Multiple Myeloma, Melanoma +27 more

Testing the Use of the Combination of Selumetinib and Olaparib or Selumetinib Alone Targeted Treatment for RAS Pathway Mutant Recurrent or Persistent Ovarian and Endometrial Cancers, A ComboMATCH Treatment Trial

NCT ID: NCT05554328

This clinical trial, called the ComboMATCH treatment trial, is studying a new way to treat certain types of ovarian and endometrial cancers. Specifically, the trial is comparing two treatments: one...

Recruiting

Phase: PHASE2 Conditions: Recurrent Ovarian Carcinoma, Recurrent Primary Peritoneal Carcinoma +2 more

Study of Chemotherapy Plus Ipatasertib for People With Solid Tumors With PTEN/AKT Mutations, A ComboMATCH Treatment Trial

NCT ID: NCT05554380

This clinical trial is studying a combination of chemotherapy (specifically a drug called paclitaxel) and a targeted therapy called ipatasertib for patients with certain types of advanced solid tum...

Recruiting

Phase: PHASE2 Conditions: Metastatic Malignant Solid Neoplasm, Unresectable Malignant Solid Neoplasm +1 more

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

NCT ID: NCT05564377

The ComboMATCH Screening Trial is a study that aims to find effective treatments for patients with advanced solid tumors, such as certain types of breast cancer and other cancers that have spread e...

Recruiting

Phase: PHASE2 Conditions: Recurrent Ovarian Carcinoma, Metastatic Malignant Solid Neoplasm +13 more

Comparing the New Anti-cancer Drug Eribulin With Chemotherapy Against the Usual Chemotherapy Alone in Metastatic Urothelial Cancer

NCT ID: NCT04579224

This clinical trial is looking at a new treatment for patients with metastatic urothelial cancer, which is a type of cancer that affects the bladder and other parts of the urinary system. Specifica...

Recruiting

Phase: PHASE3 Conditions: Metastatic Urothelial Carcinoma, Stage IV Bladder Cancer AJCC v8 +3 more

Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps

NCT ID: NCT05080673

This clinical trial is studying how often people who have had 1 or 2 non-advanced adenomas (small growths that can develop in the colon) should have follow-up colonoscopies to check for colorectal ...

Recruiting

Phase: NA Conditions: Adenocarcinoma of the Rectum, Adenocarcinoma of the Colon

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

NCT ID: NCT06418204

This clinical trial is studying the effects of cannabis and cannabinoids—substances found in marijuana—on patients who have just been diagnosed with certain types of cancer, such as breast, colorec...

Recruiting

Conditions: Melanoma, Non-Hodgkin Lymphoma +3 more

Testing the Addition of Pembrolizumab, an Immunotherapy Cancer Drug to Olaparib Alone as Therapy for Patients With Pancreatic Cancer That Has Spread With Inherited BRCA Mutations

NCT ID: NCT04548752

This clinical trial is exploring whether combining an immunotherapy drug called pembrolizumab with a cancer treatment called olaparib can work better than olaparib alone for patients with metastati...

Recruiting

Phase: PHASE2 Conditions: Metastatic Pancreatic Adenocarcinoma, Stage IV Pancreatic Cancer AJCC v8

APOLLO: A Randomized Phase II Double-Blind Study of Olaparib Versus Placebo Following Curative Intent Therapy in Patients With Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 Mutation

NCT ID: NCT04858334

The APOLLO trial is studying the effects of a medication called olaparib in patients who have had surgery for pancreatic cancer and have specific genetic mutations (in genes called BRCA1, BRCA2, or...

Recruiting

Phase: PHASE2 Conditions: Resectable Pancreatic Adenocarcinoma, Pancreatic Acinar Cell Carcinoma +5 more

Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-small Cell Lung Cancer

NCT ID: NCT05624996

This clinical trial is investigating whether adding a special type of high-dose radiation therapy called stereotactic body radiation therapy (SBRT) can improve treatment outcomes for patients with ...

Recruiting

Phase: PHASE3 Conditions: Stage III Lung Cancer AJCC v8, Stage IIB Lung Cancer AJCC v8 +1 more

Testing the Addition of MEDI4736 (Durvalumab) to Chemotherapy Before Surgery for Patients With High-Grade Upper Urinary Tract Cancer

NCT ID: NCT04628767

This clinical trial is studying whether adding a medication called durvalumab to chemotherapy can help shrink tumors in patients with high-grade upper urinary tract cancer before they have surgery....

Recruiting

Phase: PHASE2 Conditions: Renal Pelvis and Ureter Urothelial Carcinoma

Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors

NCT ID: NCT03067181

This clinical trial is investigating how well doctors can monitor patients with low-risk germ cell tumors after surgery, to see if the tumors come back. It also looks at whether two chemotherapy dr...

Recruiting

Phase: PHASE3 Conditions: Germ Cell Tumor, Childhood Extracranial Germ Cell Tumor +28 more

Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

NCT ID: NCT05235165

This clinical trial is comparing two different surgical methods to treat patients with osteosarcoma, a type of bone cancer that has spread to the lungs. The two methods are open thoracic surgery, w...

Recruiting

Phase: PHASE3 Conditions: Osteosarcoma, Metastatic Osteosarcoma +1 more

Ramucirumab and Paclitaxel or FOLFIRI in Advanced Small Bowel Cancers

NCT ID: NCT04205968

This clinical trial is investigating whether a combination of two treatments—ramucirumab and either paclitaxel or a chemotherapy regimen called FOLFIRI—can help patients with advanced small bowel c...

Recruiting

Phase: PHASE2 Conditions: Metastatic Small Intestinal Adenocarcinoma, Stage IV Small Intestinal Adenocarcinoma AJCC v8 +3 more

A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)

NCT ID: NCT04546399

This clinical trial is studying a new way to treat children and young adults who have a type of blood cancer called B-cell acute lymphoblastic leukemia (B-ALL) that has come back after initial trea...

Recruiting

Phase: PHASE2 Conditions: Down Syndrome, Recurrent B Acute Lymphoblastic Leukemia

De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

NCT ID: NCT04852887

The DEBRA trial is a research study looking at a different approach to treating early-stage hormone-sensitive breast cancer. Specifically, it aims to find out if women who have had breast-conservin...

Recruiting

Phase: PHASE3 Conditions: Stage I Breast Cancer

Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease

NCT ID: NCT05174169

This clinical trial, titled "Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease," is looking at how to best choose chemotherapy treatments for patients with Stage III colon cancer ...

Recruiting

Phase: PHASE2 Conditions: Stage III Colon Cancer

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Clinical Trials in Kingman, Arizona

50 Active Trials Found in Kingman

A Phase II/III Trial of Nivolumab, Ipilimumab, and GM-CSF in Patients With Advanced Melanoma

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-Small Cell Lung Cancer, ALCHEMIST Trial

National Cancer Institute "Cancer Moonshot Biobank"

Testing the Use of the Combination of Selumetinib and Olaparib or Selumetinib Alone Targeted Treatment for RAS Pathway Mutant Recurrent or Persistent Ovarian and Endometrial Cancers, A ComboMATCH Treatment Trial

Study of Chemotherapy Plus Ipatasertib for People With Solid Tumors With PTEN/AKT Mutations, A ComboMATCH Treatment Trial

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

Comparing the New Anti-cancer Drug Eribulin With Chemotherapy Against the Usual Chemotherapy Alone in Metastatic Urothelial Cancer

Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

Testing the Addition of Pembrolizumab, an Immunotherapy Cancer Drug to Olaparib Alone as Therapy for Patients With Pancreatic Cancer That Has Spread With Inherited BRCA Mutations

APOLLO: A Randomized Phase II Double-Blind Study of Olaparib Versus Placebo Following Curative Intent Therapy in Patients With Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 Mutation

Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-small Cell Lung Cancer

Testing the Addition of MEDI4736 (Durvalumab) to Chemotherapy Before Surgery for Patients With High-Grade Upper Urinary Tract Cancer

Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors

Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

Ramucirumab and Paclitaxel or FOLFIRI in Advanced Small Bowel Cancers

A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)

De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease