Clinical Trials for Hematopoietic Stem Cell Transplantation

Long-Term Follow-up of People Undergoing Hematopoietic Stem Cell Transplantation

NCT ID: NCT03000244

This clinical trial is looking at the long-term effects of hematopoietic stem cell transplantation (HCT), a treatment used for people with damaged bone marrow or immune systems. The study focuses o...

The Lowest Effective Dose of Post-Transplantation Cyclophosphamide in Combination With Sirolimus and Mycophenolate Mofetil as Graft-Versus-Host Disease Prophylaxis After Reduced Intensity Conditioning and Peripheral Blood Stem Cell Transplantation

NCT ID: NCT05436418

This clinical trial is exploring whether a lower dose of a medication called cyclophosphamide, given after a blood stem cell transplant, can help prevent a condition known as graft-versus-host dise...

Longitudinal Early Advance Care Planning Discussions and Documentation (LEADD) Program: An Exploratory Study in Adolescents and Young Adults (AYAs) Receiving Hematopoietic Stem Cell Transplant

NCT ID: NCT05605574

The LEADD Program is a clinical trial designed to help young adults and adolescents (ages 18 to 39) who are about to undergo a life-saving treatment called hematopoietic stem cell transplant (HSCT)...

A Phase II Study of Allogeneic Hematopoietic Stem Cell Transplant for Subjects With VEXAS (Vacuoles, E1 Enzyme, X-linked, Autoinflammatory, Somatic) Syndrome

NCT ID: NCT05027945

This clinical trial is studying whether a specific type of treatment called allogeneic hematopoietic stem cell transplant can help people with VEXAS Syndrome. VEXAS Syndrome is a rare condition tha...

Remotely Monitored, Mobile Health-supported, High Intensity Interval Training Before Hematopoietic Stem Cell Transplant

NCT ID: NCT06953648

This clinical trial is looking at how a special exercise program called REMM-HIIT, which is monitored remotely, can improve fitness and physical abilities in patients who are about to undergo stem ...

TBI/Flu/Bu/Mel Combined With Secondary UCBT in Patients With Hematological Malignancies Who Relapsed After Allo-HSCT

NCT ID: NCT06125483

This clinical trial is investigating a new treatment approach for patients with certain blood cancers, like leukemia, who have experienced a relapse after receiving a prior stem cell transplant. Th...

Metagenomics Next-generation Sequencing Approach to Detect Microbial DNA/RNA Overtime in Individuals Undergoing Hematopoietic Stem Cell Transplant

NCT ID: NCT06904053

This clinical trial is studying how a new technique called metagenomic next-generation sequencing (mNGS) can help identify germs (like bacteria, viruses, fungi, and parasites) in the blood of patie...

αβT Cell/CD19+ B Cell Depletion for Alternative Donor Allogeneic Hematopoietic Cell Transplantation (HSCT)

NCT ID: NCT06082947

This clinical trial is studying a new approach for children and young adults with blood cancers who need a stem cell transplant but don't have a matched sibling donor. The researchers are using a s...

Brain Neuronal Networks, Chemosensory and Trigeminal Functions in Allo-HSCT

NCT ID: NCT06003660

This clinical trial is looking at how taste, smell, and certain sensations in the mouth and face are affected in patients who are undergoing a specific type of treatment called allogeneic hematopoi...

Efficacy and Safety Study of Narsoplimab in Pediatric Patients With High-Risk Hematopoietic Stem Cell Transplant TMA

NCT ID: NCT05855083

This clinical trial is looking at a new treatment called narsoplimab for children who have a serious condition called thrombotic microangiopathy (TMA) after undergoing a hematopoietic stem cell tra...

Cultural Tailoring and Pilot Testing of an Inpatient Yoga Therapy Program for Cancer Patients Undergoing Hematopoietic Stem Cell Transplantation in India, Tanzania, and the United States

NCT ID: NCT05681026

This clinical trial is exploring a new yoga therapy program designed specifically for cancer patients who are about to undergo a special treatment called hematopoietic stem cell transplantation (HS...

Moxibustion for the Prevention of Hemorrhagic Cystitis After Allo-HSCT

NCT ID: NCT06198517

This clinical trial is studying how a traditional treatment called moxibustion might help prevent a condition known as hemorrhagic cystitis in patients receiving a type of stem cell transplant call...

Tissue-resident Immune Cell Subsets in aGVHD

NCT ID: NCT06708507

This clinical trial is studying how certain immune cells in the body may affect the development and severity of a condition called acute graft-versus-host disease (aGVHD). This condition can occur ...

Posaconazole Tablet As Primary Prophylaxis of HSCT Patients with Gastrointestinal GVHD

NCT ID: NCT06698211

Employment Support After Hematopoietic Stem Cell Transplantation

NCT ID: NCT06494423

This clinical trial is looking at a program called Work Support (WorkS) that helps people who have recently received a specific type of treatment called allogeneic stem cell transplantation (HSCT) ...

Dietary Manipulation of the Microbiome-metabolomic Axis for Mitigating GVHD in Allo HCT Patients

NCT ID: NCT02763033

This clinical trial is studying a dietary supplement made from potato-based resistant starch to see if it can help reduce a condition called acute Graft-Versus-Host Disease (GVHD) in patients under...

HCMV Breakthrough Infections During Letermovir Prophylaxis

NCT ID: NCT06339892

This clinical trial is studying how to better monitor infections caused by the cytomegalovirus (HCMV) in patients who have received a stem cell transplant and are taking a medication called letermo...

Respiratory Microbioma and Respiratory Complications After Hematopoietic Stem Cell Transplantion

NCT ID: NCT06639750

This clinical trial is looking to understand the relationship between the respiratory microbiome (the community of viruses and bacteria in our lungs) and respiratory complications that can occur af...

A Study to Assess CSF1R-related Leukoencephalopathy After Stem Cell Transplantation

NCT ID: NCT04503213

Inotuzumab Ozogamicin in the Treatment of MRD+ After HSCT of ALL

NCT ID: NCT05940961

This clinical trial is looking at a new treatment option called Inotuzumab Ozogamicin for patients with a type of blood cancer known as Acute Lymphoblastic Leukemia (ALL) who have Minimal Residual ...