Clinical Trials for Insulin Resistance

Trial of the Combination of Alpha-Lipoic Acid and Mirabegron in Women and in Men With Obesity

NCT ID: NCT05713799

This clinical trial is exploring whether a combination of two substances—mirabegron, which is a medication, and alpha-lipoic acid, a dietary supplement—can help people with obesity process food bet...

Human Models of Selective Insulin Resistance: Pancreatic Clamp

NCT ID: NCT06558422

This clinical trial, titled "Human Models of Selective Insulin Resistance: Pancreatic Clamp," is studying how lowering insulin levels affects the way the liver produces glucose and fat in people wh...

Everolimus Aging Study

NCT ID: NCT05835999

The Everolimus Aging Study is a research trial that aims to see if a medication called everolimus can help improve signs of aging in adults who are between 55 and 80 years old and have insulin resi...

Small Extracellular Vesicles and Insulin Action

NCT ID: NCT05933707

This clinical trial is exploring why some individuals with obesity do not develop related health problems, like type 2 diabetes and heart disease, while others do. The researchers are particularly ...

Acute Exercise on Brain Insulin Sensitivity

NCT ID: NCT05853913

This clinical trial is studying how a single session of exercise affects insulin sensitivity in the brain, particularly in middle-aged and older adults. Insulin sensitivity refers to how well your ...

Role of Aging and Individual Variation in Exercise Training Responsiveness

NCT ID: NCT06471569

This clinical trial is looking at how aging affects the body’s ability to respond to exercise, particularly in older adults who have previously completed a structured exercise program. The study ai...

Exercise Effects on Adipose Tissue Structure and Function

NCT ID: NCT04812314

This clinical trial is studying how exercise affects fat tissue and overall health in people who are overweight or have metabolic issues, like insulin resistance. Participants will be divided into ...

Modulating Energy Density in Time-Restricted Eating

NCT ID: NCT06259435

This clinical trial is looking to see how a specific eating pattern called time-restricted eating affects older adults with obesity and insulin resistance. In this study, participants will fast for...

Probiotics and Insulin Resistance in Obese Asthmatics

NCT ID: NCT05949255

Extracellular Vesicle Cargo in Obesity and Type 2 Diabetes

NCT ID: NCT06401876

This clinical trial, titled "Extracellular Vesicle Cargo in Obesity and Type 2 Diabetes," is studying how certain substances in the blood relate to diabetes and obesity. Researchers want to underst...

Mitigating the Pro-inflammatory Phenotype of Obesity

NCT ID: NCT04934228

This clinical trial is studying the effects of a medication called clonidine, which aims to reduce inflammation related to obesity over a period of four weeks. Researchers believe that by blocking ...

A Comparison of Neuromuscular Recruitment in Trained and Untrained Adults

NCT ID: NCT06820658

This clinical trial is studying how the nervous system controls muscle activity in older adults, specifically those aged 60 to 85. The researchers want to compare how well the nervous system works ...

The Effects of Fresh Mango Consumption on Cardiometabolic Outcomes in Free-living Individuals With Prediabetes

NCT ID: NCT06159543

This clinical trial is studying how eating fresh mango affects health in people with prediabetes. Specifically, researchers want to learn if eating 1.5 cups of mango each day for 12 weeks can impro...

Role of Insulin Action in Psoriasis Pathogenesis

NCT ID: NCT06242847

This clinical trial is focused on understanding the role of insulin in people with plaque psoriasis, a common skin condition characterized by red, scaly patches. Researchers want to find out if ins...

Therapeutic Strategies for Type 2 Diabetes Based on Lifestyle Changes: Plant-based Diet and Physical Exercise

NCT ID: NCT06959043

This clinical trial is exploring how a strict vegetarian diet, regular exercise, and probiotics can help people with type 2 diabetes improve their health. The researchers want to see if these lifes...

Hepatic Elastography-Enhanced Lifestyle Modification in MASLD

NCT ID: NCT06826807

Reversal of Lipid-Induced Insulin Resistance

NCT ID: NCT02193295

This clinical trial is exploring whether losing weight can help improve insulin sensitivity in individuals who are insulin resistant and have a family history of type 2 diabetes. Insulin resistance...

The Efficacy of Pedometer-motivated Physical Activity for the Management of Patients With MASLD.

NCT ID: NCT06334666

Metabolic Effects of Angiotensin-(1-7)

NCT ID: NCT02646475

This clinical trial is investigating the effects of a substance called angiotensin-(1-7) on people who are dealing with obesity and insulin resistance. Insulin resistance happens when the body does...

Sodium Bicarbonate and Mitochondrial Energetics in Persons With CKD

NCT ID: NCT04984226

This clinical trial is looking at how sodium bicarbonate, a common substance, may help improve muscle health in people with chronic kidney disease (CKD). CKD can lead to a condition called metaboli...