Clinical Trials for Insulin Resistance

Find clinical trials for insulin resistance. Discover research opportunities and treatment options in your area.

103 Active Trials Found

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Trial of the Combination of Alpha-Lipoic Acid and Mirabegron in Women and in Men With Obesity

NCT ID: NCT05713799

This clinical trial is exploring whether a combination of two substances—mirabegron, which is a medication, and alpha-lipoic acid, a dietary supplement—can help people with obesity process food bet...

Not yet recruiting

Phase: PHASE2 Type: interventional Locations: Bethesda, Maryland, United States

Study of the Effect of Innate on the Inflammatory Response to Endotoxin

NCT ID: NCT01143480

This clinical trial is studying how certain genes and proteins in our blood cells react to environmental factors that might lead to inflammation. Inflammation is a natural response by our immune sy...

Type: observational Locations: Research Triangle Park, North Carolina, United States, Research Triangle Park, North Carolina, United States

Effects of Sourdough Fermentation Duration and Acid Development on Postprandial Blood Glucose in Prediabetic Adults

NCT ID: NCT06925451

This clinical trial is studying how the length of fermentation time for sourdough bread affects blood sugar levels after eating, specifically in adults who have prediabetes. Researchers want to fin...

Phase: NA Type: interventional Locations: Phoenix, Arizona, United States

Effect of Add-on SGLT2i, TZD, or Combination Therapy in Type 2 Diabetes Patients on DPP4 Inhibitors

NCT ID: NCT07108985

This clinical trial is studying how adding new diabetes medications might help people with type 2 diabetes who are already taking a certain kind of medicine called DPP4 inhibitors. The researchers ...

Not yet recruiting

Phase: PHASE4 Type: interventional Locations: Seoul, Korea, Republic Of

Effect of Endoscopic Sleeve Gastroplasty in Patients With Obesity and MASH: A Randomized Controlled Trial

NCT ID: NCT06138821

This clinical trial is studying the effects of a procedure called endoscopic sleeve gastroplasty (ESG) in patients with obesity and a liver condition known as metabolic dysfunction-associated steat...

Phase: NA Type: interventional Locations: Boston, Massachusetts, United States, Boston, Massachusetts, United States

ActiveGirls: Physical Activity, Hormone Health, and Diabetes Risk in Early Adolescence

NCT ID: NCT07102797

This study, called ActiveGirls, is looking at how a special physical activity program might help girls aged 8 to 12 who are at higher risk for a condition called Polycystic Ovary Syndrome (PCOS) an...

Not yet recruiting

Phase: NA Type: interventional

A Comparison of Neuromuscular Recruitment in Trained and Untrained Adults

NCT ID: NCT06820658

This clinical trial is studying how the nervous system controls muscle activity in older adults, specifically those aged 60 to 85. The researchers want to compare how well the nervous system works ...

Type: observational Locations: Rochester, Minnesota, United States

Human Models of Selective Insulin Resistance: Alpelisib, Part I

NCT ID: NCT06354088

This clinical trial, called "Human Models of Selective Insulin Resistance: Alpelisib, Part I," is designed to investigate how the hormone insulin works in healthy adults compared to those who are a...

Phase: PHASE1 Type: interventional Locations: New York, New York, United States

Role of Insulin Action in Psoriasis Pathogenesis

NCT ID: NCT06242847

This clinical trial is focused on understanding the role of insulin in people with plaque psoriasis, a common skin condition characterized by red, scaly patches. Researchers want to find out if ins...

Type: observational Locations: New York, New York, United States

Human Models of Selective Insulin Resistance: Pancreatic Clamp

NCT ID: NCT06558422

This clinical trial, titled "Human Models of Selective Insulin Resistance: Pancreatic Clamp," is studying how lowering insulin levels affects the way the liver produces glucose and fat in people wh...

Not yet recruiting

Phase: PHASE1 Type: interventional Locations: New York, New York, United States

Everolimus Aging Study

NCT ID: NCT05835999

The Everolimus Aging Study is a research trial that aims to see if a medication called everolimus can help improve signs of aging in adults who are between 55 and 80 years old and have insulin resi...

Phase: PHASE2 Type: interventional Locations: Madison, Wisconsin, United States

Small Extracellular Vesicles and Insulin Action

NCT ID: NCT05933707

This clinical trial is exploring why some individuals with obesity do not develop related health problems, like type 2 diabetes and heart disease, while others do. The researchers are particularly ...

Phase: NA Type: interventional Locations: Saint Louis, Missouri, United States

Acute Exercise on Brain Insulin Sensitivity

NCT ID: NCT05853913

This clinical trial is studying how a single session of exercise affects insulin sensitivity in the brain, particularly in middle-aged and older adults. Insulin sensitivity refers to how well your ...

Phase: PHASE2 Type: interventional Locations: New Brunswick, New Jersey, United States, New Brunswick, New Jersey, United States +2 more

Role of Aging and Individual Variation in Exercise Training Responsiveness

NCT ID: NCT06471569

This clinical trial is looking at how aging affects the body’s ability to respond to exercise, particularly in older adults who have previously completed a structured exercise program. The study ai...

Phase: NA Type: interventional Locations: Durham, North Carolina, United States

Exercise Effects on Adipose Tissue Structure and Function

NCT ID: NCT04812314

This clinical trial is studying how exercise affects fat tissue and overall health in people who are overweight or have metabolic issues, like insulin resistance. Participants will be divided into ...

Phase: NA Type: interventional Locations: Ann Arbor, Michigan, United States, Ann Arbor, Michigan, United States

Modulating Energy Density in Time-Restricted Eating

NCT ID: NCT06259435

This clinical trial is looking to see how a specific eating pattern called time-restricted eating affects older adults with obesity and insulin resistance. In this study, participants will fast for...

Phase: NA Type: interventional Locations: Baton Rouge, Louisiana, United States

Probiotics and Insulin Resistance in Obese Asthmatics

NCT ID: NCT05949255

This small, early-stage study at the University of Alabama at Birmingham is testing whether taking a daily probiotic capsule for 12 weeks can change the bacteria and chemicals in the airways and gu...

Enrolling by invitation

Phase: NA Type: interventional Locations: Birmingham, Alabama, United States

Mitigating the Pro-inflammatory Phenotype of Obesity

NCT ID: NCT04934228

This clinical trial is studying the effects of a medication called clonidine, which aims to reduce inflammation related to obesity over a period of four weeks. Researchers believe that by blocking ...

Phase: PHASE1 Type: interventional Locations: Kansas City, Kansas, United States

The Effects of Fresh Mango Consumption on Cardiometabolic Outcomes in Free-living Individuals With Prediabetes

NCT ID: NCT06159543

This clinical trial is studying how eating fresh mango affects health in people with prediabetes. Specifically, researchers want to learn if eating 1.5 cups of mango each day for 12 weeks can impro...

Phase: NA Type: interventional Locations: Loma Linda, California, United States

Therapeutic Strategies for Type 2 Diabetes Based on Lifestyle Changes: Plant-based Diet and Physical Exercise

NCT ID: NCT06959043

This clinical trial is exploring how a strict vegetarian diet, regular exercise, and probiotics can help people with type 2 diabetes improve their health. The researchers want to see if these lifes...

Phase: NA Type: interventional Locations: São Paulo, Brazil

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