Clinical Trials for Insulin Sensitivity

Find clinical trials for insulin sensitivity. Discover research opportunities and treatment options in your area.

34 Active Trials Found

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A Study to Evaluate the Effect of Retatrutide on Insulin Secretion and Insulin Sensitivity in Adult Participants With Type 2 Diabetes Mellitus

NCT ID: NCT06982859

This clinical trial is studying a medication called retatrutide to see how it affects insulin secretion and sensitivity in adults with Type 2 Diabetes Mellitus (T2DM). Insulin is a hormone that hel...

Recruiting

Phase: PHASE1 Type: interventional Locations: Neuss, Nordrhein Westfalen, Germany

Aging Resilience Through Microbiota Optimization and Regulation

NCT ID: NCT06649981

This clinical trial is investigating a new approach to improve muscle strength and overall health in older adults. Researchers believe that changes in the gut bacteria, or microbiota, as people age...

Recruiting

Phase: PHASE1 Type: interventional Locations: Santiago, Región Metropolitana, Chile, Santiago, Región Metropolitana, Chile +2 more

Lifestyle Intervention for Improving Insulin Resistance and Concern for Health

NCT ID: NCT05649176

This clinical trial is looking at how a special diet and exercise program can help older adults who have insulin resistance—a condition where the body doesn’t use insulin well—and a lack of motivat...

Recruiting

Phase: NA Type: interventional Locations: Baton Rouge, Louisiana, United States

MANATEE-T1D: Metformin ANd AutomaTEd Insulin Delivery System Effects on Renal Vascular Resistance, Insulin Sensitivity, and Cardiometabolic Function in Youth With Type 1 Diabetes

NCT ID: NCT05065372

The MANATEE-T1D trial is studying how a medication called metformin, when used with an automated insulin delivery system, affects kidney health and insulin use in young people with type 1 diabetes....

Recruiting

Phase: PHASE1 Type: interventional Locations: Aurora, Colorado, United States, Aurora, Colorado, United States +2 more

Pubertal Blockade and Estradiol Effects on Cardiometabolic Health for Transitioning Youth

NCT ID: NCT04596592

This clinical trial is studying how estradiol, a hormone often taken by transgender females, affects insulin sensitivity (how well the body uses sugar) and blood vessel function. The researchers wa...

Recruiting

Type: observational Locations: Aurora, Colorado, United States

Evaluation of Molecular Hydrogen Supplementation to Enhance the Efficacy of Weight Loss Retreat in Overweight and Obese Adolescents

NCT ID: NCT06961110

This clinical trial is studying whether adding molecular hydrogen supplements can help overweight and obese teenagers lose weight more effectively during a 4-week weight loss retreat. The researche...

Recruiting

Phase: NA Type: interventional Locations: Olomouc, , Czech Republic, Olomouc, Czech Republic, Czechia

Mechanisms of Ultrasound Neuromodulation Effects in Diabetes

NCT ID: NCT06042517

This clinical trial is studying how a special type of ultrasound treatment can improve insulin sensitivity in people with Type 2 diabetes. Insulin sensitivity is how well your body responds to insu...

Recruiting

Phase: NA Type: interventional Locations: New Haven, Connecticut, United States

Saccharin and Acesulfame Potassium Consumption and Glucose Homeostasis in Older Adults With Prediabetes

NCT ID: NCT05441982

This clinical trial is studying how two non-nutritive sweeteners, saccharin and acesulfame potassium, affect blood sugar control in older adults who have prediabetes. Previous research has hinted t...

Recruiting

Phase: NA Type: interventional Locations: Blacksburg, Virginia, United States

Non-Nutritive Sweetener Consumption and Glucose Homeostasis in Older Adults With Prediabetes

NCT ID: NCT05337098

This clinical trial is exploring how certain non-nutritive sweeteners, specifically sucralose and aspartame, affect blood sugar control in older adults who have prediabetes. Previous studies sugges...

Recruiting

Phase: NA Type: interventional Locations: Blacksburg, Virginia, United States

Physical Activity and Insulin Sensitivity Dynamics

NCT ID: NCT06776094

This clinical trial is exploring how a single session of exercise can improve the way muscles respond to insulin, which helps regulate blood sugar levels. Specifically, the study will look at how q...

Recruiting

Phase: NA Type: interventional Locations: Copenhagen, , Denmark

Evaluating the Efficacy of Topical Insulin for the Restoration of Ocular Surface Interface in Dry Eye Disease.

NCT ID: NCT06939959

This clinical trial is studying the effectiveness of insulin eye drops as a treatment for moderate to severe dry eye disease. Researchers want to see if these insulin drops can improve the health o...

Recruiting

Phase: PHASE4 Type: interventional Locations: Peshawar, Khyber Pukhtunkhwa, Pakistan

Metabolic Adaptations to Weight Loss With and Without Exercise

NCT ID: NCT05806801

This clinical trial is studying how adding exercise to a weight loss program affects health, especially focusing on fat tissue in the abdomen. Researchers want to understand how the combination of ...

Recruiting

Phase: NA Type: interventional Locations: Ann Arbor, Michigan, United States, Ann Arbor, Michigan, United States

The Acute T-Rex (Timing of Resistance Exercise) Study

NCT ID: NCT06366399

The Acute T-Rex Study is looking at how the timing of resistance exercise—either in the morning or evening—affects insulin sensitivity and sleep in adults who may be at risk for Type 2 diabetes. In...

Recruiting

Phase: NA Type: interventional Locations: Salt Lake City, Utah, United States

Effect of GLP1 Receptor Agonist on Brain Insulin Responsiveness

NCT ID: NCT06487832

This clinical trial is studying how a medication called semaglutide, which acts on a hormone known as GLP-1, affects the way the brain responds to insulin. Insulin is a hormone that helps control b...

Recruiting

Phase: NA Type: interventional Locations: Tübingen, , Germany

The Importance of Insulin Action in the Brain for the Immune System During Physical Activity

NCT ID: NCT06552130

This clinical trial is studying how insulin works in the brain and its effects on the immune system during physical activity. Researchers want to understand how insulin delivery, given as a nasal s...

Recruiting

Phase: NA Type: interventional Locations: Ulm, , Germany

Postprandial Metabolome and Metabolic Flexibility

NCT ID: NCT06878781

This clinical trial is studying how our bodies use different sources of energy after eating meals with varying amounts of carbohydrates, proteins, and fats. The researchers want to understand somet...

Recruiting

Phase: NA Type: interventional Locations: Mexico City, , Mexico

Low Dose Fat-Induced Insulin Resistance

NCT ID: NCT03479671

This clinical trial is studying how a low dose of fatty acids affects insulin resistance in healthy individuals. Insulin resistance is a condition where the body does not respond properly to insuli...

Recruiting

Phase: EARLY_PHASE1 Type: interventional Locations: Philadelphia, Pennsylvania, United States

Effect of Pulsatile Hormone Administration on Insulin Action

NCT ID: NCT06216665

This clinical trial is examining how insulin is delivered to the body and how that affects insulin sensitivity, which is how well the body responds to insulin. Insulin helps control blood sugar lev...

Recruiting

Phase: NA Type: interventional Locations: Baton Rouge, Louisiana, United States

Effect of Sleep Extension on Ceramides in People with Overweight and Obesity

NCT ID: NCT06180837

This clinical trial is studying how getting more sleep can affect certain fats in the blood called ceramides and how the body responds to insulin in people who are overweight or obese. The goal is ...

Recruiting

Phase: NA Type: interventional Locations: Salt Lake City, Utah, United States

Circadian Intervention to Improve Cardiometabolic Health

NCT ID: NCT05943626

This clinical trial is looking at how changing daily habits related to light exposure and eating can help improve health in people who are overweight or obese and don’t get enough sleep. The study ...

Recruiting

Phase: NA Type: interventional Locations: Salt Lake City, Utah, United States

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