Clinical Trials for Respiratory Failure

Patients Comfort During Highflow Oxygen Therapy With Asymmetrical Prongs

NCT ID: NCT06778291

This clinical trial is studying how comfortable patients feel while using a high-flow nasal cannula (HFNC) for oxygen therapy. HFNC is a device that provides heated and humidified oxygen to help pe...

Low and High Flow Suctioning in Intubated Infants

NCT ID: NCT06443970

This clinical trial is looking at two different methods of suctioning the airways of intubated infants who are having trouble breathing. The researchers want to compare a new suction device called ...

The Family Perspectives Project Pilot Trial

NCT ID: NCT06039501

The Family Perspectives Project Pilot Trial is a research study aimed at improving communication and emotional support for families of critically ill patients, particularly those experiencing respi...

Early Speaking Valve in Ventilator Weaning: Effects on Communication, Depression, and Quality of Life

NCT ID: NCT07005596

This clinical trial is studying how using a special speaking valve can help patients who are on ventilators communicate better and improve their emotional well-being during the process of getting o...

Improving Psychological Outcomes for Acute Respiratory Failure Survivors Using a Self-Management Intervention

NCT ID: NCT06341972

This clinical trial is exploring a new way to help patients who have survived severe breathing problems and spent time in the intensive care unit (ICU). Many of these patients may experience anxiet...

Diaphragmatic Speckle Tracking to Guide Diaphragm-Protective Ventilatory Support: A Study of Feasibility and Efficacy.

NCT ID: NCT06996665

This clinical trial is investigating a new method called diaphragmatic speckle tracking ultrasound to help improve breathing support for patients who are on mechanical ventilation due to respirator...

A Post Market Surveillance Study of the Hemovent Extracorporeal Cardiopulmonary Support System:The MOBYBOX Trial

NCT ID: NCT04183660

The MOBYBOX Trial is a study designed to evaluate the safety and effectiveness of a new medical device called the Hemovent Extracorporeal Cardiopulmonary Support System. This device helps support p...

Combining Chest X-Ray and Arterial Blood Gas Findings to Predict Need for Mechanical Ventilation in Critically Ill Patients

NCT ID: NCT07001696

This clinical trial is studying how well a new machine learning model can predict whether critically ill patients will need mechanical ventilation, which is a machine that helps patients breathe wh...

Precision Ventilation vs Standard Care for Acute Respiratory Distress Syndrome

NCT ID: NCT06066502

This clinical trial is studying two different ways of helping patients with Acute Respiratory Distress Syndrome (ARDS), a serious condition that affects breathing. The trial aims to find out if a p...

The Efficacy of P0.1-guided Sedation Protocol in Critically Ill Patients Receiving Invasive Mechanical Ventilation: A Randomized Controlled Trial

NCT ID: NCT06203405

This clinical trial is investigating a new approach to sedation for patients who are critically ill and require mechanical ventilation, which is a machine that helps them breathe. The study is comp...

Respiratory Knowledge Portal Computer and Phone Application to Improve Quality of Mechanical Ventilation by Reducing the Number of Ventilator Associated Events, Injury Created by the Ventilator and Unsafe Setting of Alarms.

NCT ID: NCT06737432

This clinical trial is studying a new tool designed to improve the care of patients on mechanical ventilation in intensive care units (ICUs). It focuses on reducing complications known as ventilato...

Optimizing Care in Critically Ill at UCHealth by Liberalizing the Target O2 in Mechanically-ventilated ICU Patients

NCT ID: NCT06501118

This clinical trial is looking at how adjusting oxygen levels can improve care for patients who are critically ill and on a ventilator in the ICU. The study aims to see if keeping oxygen levels bet...

Investigating the Impact of Sepsis Phenotypes on Antibiotic Treatment in Patients With Severe Pneumonia and Sepsis

NCT ID: NCT06977165

The SIPRES Study is a research trial aimed at understanding why antibiotics work differently for patients with severe pneumonia and sepsis, which is a serious condition that can occur when pneumoni...

A Trial Comparing High-Flow Nasal Cannula Versus Noninvasive Ventilation on Reintubation and Post-Extubation Respiratory Failure in High-Risk Patients With Systolic Heart Failure

NCT ID: NCT06671015

This clinical trial is looking to compare two types of breathing support methods for patients with systolic heart failure, which is a condition that affects the heart's ability to pump blood effect...

Quantification of Inspiratory Effort Through Nasal Pressure in Patients Undergoing Weaning From Invasive Mechanical Ventilation and Correlation With Clinical Outcomes

NCT ID: NCT05282238

This clinical trial is studying how to better measure breathing effort in patients who are being taken off invasive mechanical ventilation (a machine that helps them breathe). The goal is to find a...

Perioperative Risk Factors Related to the Prognosis of Lung Transplantation: A Retrospective Study

NCT ID: NCT06922916

This clinical trial is looking into how factors related to anesthesia during lung transplantation can affect patients' recovery and outcomes. The study will analyze data from patients aged 18 and o...

High-flow Nasal Oxygenation for Apnoeic Oxygenation During Intubation of the Critically Ill

NCT ID: NCT05883137

This clinical trial is studying a new device called Optiflow Switch, which is designed to improve the safety of a procedure called intubation in critically ill patients. Intubation is when a tube i...

Drainage Of Pleural Effusions in the Intensive Care Unit (DOPE-ICU) - Feasibility Trial

NCT ID: NCT06709456

The DOPE-ICU trial is studying whether using ultrasound to guide the drainage of fluid around the lungs, known as pleural effusions, is effective for patients in the intensive care unit (ICU) who a...

Distribution of Ventilation, Respiratory Drive and Gas Exchange: Measurements and Monitoring

NCT ID: NCT05462600

Preventing Cardiovascular Collapse With Vasopressors During Tracheal Intubation

NCT ID: NCT05014581

The PREVENTION trial is studying how to prevent heart problems during a medical procedure called tracheal intubation, which is often needed for critically ill patients who have trouble breathing. S...