Clinical Trials for Cardiopulmonary Bypass

ARTEMIS: Ravulizumab to Protect Patients With CKD From CSA-AKI and MAKE

NCT ID: NCT05746559

The ARTEMIS clinical trial is studying whether a single dose of a medication called ravulizumab can help protect patients with chronic kidney disease (CKD) from acute kidney injury (AKI) after they...

Nitric Oxide for Reduced Intensive Support in Cardiac Surgery With Cardiopulmonary Bypass

NCT ID: NCT06702553

This clinical trial is studying the use of inhaled nitric oxide (iNO) during cardiac surgery to see if it can help reduce serious complications after surgery. These complications can include heart ...

Autologous Cold-stored Apheresis Platelets

NCT ID: NCT07064954

This clinical trial, called the Auto-PLTS Study, is looking at a new way to help patients who are having planned complex heart surgery. Normally, patients receive donated platelets from other peopl...

Ultrasound Guided Bilateral Pectoral Nerve Block Versus Bilateral Transverse Thoracic Plane Block In Pediatric Patients Undergoing Corrective Cardiac Surgeries Requiring Cardiopulmonary Bypass Via Median Sternotomy

NCT ID: NCT06984276

This clinical trial is investigating two different methods of pain control for young children undergoing heart surgery. Specifically, it compares the effectiveness of a technique called the pectora...

Intravenous Fish Oil Based Lipid Emulsion to Enhance Recovery in High-Risk Cardiac Surgery Patients

NCT ID: NCT06279793

The MODIFY CSX study is a clinical trial designed to see if giving high-risk cardiac surgery patients a special fish oil-based nutrient can help them recover better after surgery. The study will en...

Prophylactic Methylprednisolone for Renal Protection in Cardiac Surgeries With Cardiopulmonary Bypass

NCT ID: NCT06917859

This clinical trial is studying whether a single dose of a medication called methylprednisolone, given during heart surgery, can help protect the kidneys from damage that sometimes occurs after sur...

Effect of Low Tidal Volume Ventilation on Postoperative Delirium

NCT ID: NCT06752421

This clinical trial is investigating how a specific type of breathing support, called low tidal volume (LTV) ventilation, may help reduce the risk of postoperative delirium in patients undergoing h...

Influence of Oxygenator Selection on Platelet Function and Rotational Thromboelastometry Following Cardiopulmonary Bypass

NCT ID: NCT05588011

This clinical trial is studying how different types of oxygenators, which are used in heart surgeries, affect the function of platelets in the blood. Platelets are small cells that help stop bleedi...

Amobarbital and Cardiopulmonary Bypass

NCT ID: NCT06757868

This clinical trial is studying the effects of a medication called amobarbital during heart surgery that involves a procedure known as cardiopulmonary bypass. Researchers want to understand if amob...

Research on Circulation Management Strategy Based on Oxygen Metabolism Balance After CHD Surgery

NCT ID: NCT06747546

Cardiopulmonary Bypass Induced Red Blood Cell Lysis

NCT ID: NCT05189262

This clinical trial is looking at how a medical procedure called cardiopulmonary bypass (CPB) can affect red blood cells during heart surgery. Researchers want to understand how CPB might cause dam...

Protective Effect of RIPC Against Negative Inflammatory Response and Organ Dysfunction After Cardiovascular Surgery (Panda VII)

NCT ID: NCT06707350

The clinical trial titled "Protective Effect of RIPC Against Negative Inflammatory Response and Organ Dysfunction After Cardiovascular Surgery" aims to explore a technique called remote ischaemic p...

Protective Effect of Probacine Against Negative Gut Metabolism and Organ Dysfunction After Cardiovascular Surgery (PANDA IV)

NCT ID: NCT04444362

This clinical trial is studying the effects of a program called Inspiratory Muscle Training (IMT) on patients undergoing cardiac surgery. IMT consists of breathing exercises that help strengthen th...

Calcium Administration in Cardiac Surgery

NCT ID: NCT03772990

This clinical trial is studying the effects of calcium administration during cardiac surgery, specifically when patients are being taken off a machine called cardiopulmonary bypass (CPB). This mach...

Delayed Cold-Stored Platelets -PLTS-1

NCT ID: NCT06147531

The PLTS-1 clinical trial is looking at a new way to store platelets, which are important for helping blood to clot, especially during cardiac surgery. Researchers want to find out if using cold-st...

Heart Lung Machine Registry

NCT ID: NCT06159517

**Summary of the Heart Lung Machine Registry Trial** The Heart Lung Machine Registry is a clinical trial that is looking at the safety and effectiveness of specific medical devices used during hea...

Neutrophil Phenotypic Profiling and Acute Lung Injury in Patients After Cardiopulmonary Bypass (CPB)

NCT ID: NCT04296071

This clinical trial is studying how a procedure called cardiopulmonary bypass (CPB) can lead to a serious condition known as acute lung injury (ALI) in young children. After heart surgery that requ...

Effect of Methylprednisolone on Systemic Inflammatory Response During Pediatric Congenital Open-Heart Surgery

NCT ID: NCT05927233

This clinical trial is studying the effects of a steroid called methylprednisolone on inflammation in children who are having heart surgery. Specifically, it looks at how this steroid might help re...

The Effect of ACT and Tranexamic Acid on Bleeding in Cardiac Surgery

NCT ID: NCT06109155

This clinical trial is studying how different doses of a medication called tranexamic acid and the levels of a test known as Activated Clotting Time (ACT) affect bleeding during heart surgery. The ...

Restrictive Transfusion StratEgy Adjusted by SvO2 During Cardiac Surgery

NCT ID: NCT05740059

This clinical trial is studying a new approach to blood transfusions for patients undergoing heart surgery. The goal is to see if a method that adjusts transfusion needs based on a specific measure...