Clinical Trials for Periodontitis

Evaluation of the Systemic Burden of Non-surgical Periodontal Therapy: A Randomized Clinical Trial on Five Different Treatment Protocols

NCT ID: NCT07077122

This clinical trial is looking at how different ways of cleaning teeth below the gumline—called non-surgical periodontal therapy—might affect the body’s overall inflammation and the presence of bac...

Effect of Photodynamic Therapy as an Adjunct to Non-Surgical Treatment of Periodontitis

NCT ID: NCT07070453

This clinical trial is studying a new way to help treat periodontitis, which is a serious gum disease caused by harmful bacteria around the teeth. The trial looks at using photodynamic therapy (PDT...

Hyaluronic Acid and Octenidine Gel as an Adjunct to Non-surgical Periodontal Treatment

NCT ID: NCT06522438

This clinical trial is investigating whether a special gel that contains Hyaluronic Acid and Octenidine can help improve healing when used alongside standard non-surgical treatment for gum disease ...

Investigation of the Relationship Between Periodontitis and Alzheimer's Disease in Terms of Blood Parameters

NCT ID: NCT07069244

This clinical trial is exploring whether there is a connection between gum disease (called periodontitis) and Alzheimer’s disease, focusing on how certain blood tests might help understand this rel...

Para-Probiotic Oral Care in Periodontal Patients With Type 2 Diabetes

NCT ID: NCT07069166

This clinical trial is studying whether using special oral care products containing “para-probiotics” can help improve gum health and blood sugar control in people with type 2 diabetes who also hav...

Therapeutic Effect of Manuka Honey Oral Rinse on Fibroblast Growth Factor-21 in Periodontitis Patients Undergoing Hemodialysis

NCT ID: NCT06726876

This clinical trial is looking at whether using a special mouth rinse made with Manuka honey can help people with periodontitis (a serious gum disease) who are also undergoing hemodialysis for kidn...

The Role of Toll-like Receptor-4 in Periodontitis Patients With End-stage Renal Disease in a Sample of Egyptian Population

NCT ID: NCT06755372

This clinical trial is looking at how a specific gene, called TLR4, might be linked to gum disease (periodontitis) in people who have severe kidney failure, known as end-stage renal disease (ESRD)....

Electromyographic Assessment of Sleep Bruxism in Patients With Stage III and IV Periodontitis

NCT ID: NCT07053865

This clinical trial is studying the connection between advanced gum disease (called Stage III and IV periodontitis) and sleep bruxism, which is when a person grinds or clenches their teeth during s...

Changes in Bruxism Activity After Periodontal Treatment in Patients With Periodontitis

NCT ID: NCT07053878

This clinical trial is studying whether treating gum disease (called periodontitis) can help reduce teeth grinding and clenching, known as bruxism, which can happen both during the day and while sl...

Periodontitis Treatment and Heart Failure

NCT ID: NCT07036289

PRF as Adjunct to Subgingival Instrumentation in Step 2 Periodontal Therapy

NCT ID: NCT07013682

This clinical trial is studying the effects of a treatment called platelet-rich fibrin (PRF) on patients with periodontitis, a serious gum disease that can lead to tooth loss if not treated. The re...

Targeting of Preventive Treatment for Adolescents at Risk of Oral Diseases

NCT ID: NCT06286501

This clinical trial is looking at ways to help prevent oral diseases, like tooth decay and gum disease, in young people aged 14 to 16 years old. The researchers want to find out if a special treatm...

Evaluation of Clinical and Radiological Outcomes Following the Treatment of Periodontal Intraosseous Defects Using Autogenous Tooth-derived Graft or Autogenous Bone Graft With Enamel Matrix Derivatives. A 12-month Randomized Controlled Clinical Trial.

NCT ID: NCT06991998

Assessment of Tooth Mobility After Non-surgical Periodontal Treatment Followed by Tooth Splinting

NCT ID: NCT06929676

This clinical trial is studying how non-surgical treatment for gum disease (periodontitis) affects the movement of front teeth that are wobbly. The researchers will enroll 20 patients with moderate...

Powered vs. Manual Toothbrushing in Stage 3-4 Periodontitis

NCT ID: NCT06980714

Comparative Effects of Two Oral Antiseptics Used as an Adjuvant in the Treatment of Periodontitis

NCT ID: NCT06967402

This clinical trial is studying two different mouthwashes used to help treat gum disease, specifically periodontitis. One mouthwash contains a higher concentration of chlorhexidine (0.2%), while th...

Endoscope-assisted Flapless Approach Versus Papillary Preservation Technique in Periodontal Regeneration.

NCT ID: NCT06978036

This clinical trial is studying two different surgical techniques for treating periodontal disease, which is a serious gum infection that damages the soft tissue and bone supporting your teeth. The...

Periodontitis and Inflammation in Children With Down Syndrome/Trisomy 21: Study on Biological Samples

NCT ID: NCT05970965

This clinical trial is studying how children with Down syndrome (also known as Trisomy 21) experience gum disease, called periodontitis. Researchers want to understand the different types of immune...

Evaluation of Salivary Biomarker Levels in Individuals With Different Periodontal Conditions

NCT ID: NCT06558136

This clinical trial is studying the levels of specific proteins in saliva that may help diagnose different types of gum disease, including healthy gums, gingivitis (inflammation of the gums), and p...

Periodontitis and Inflammation: Study on Biological Samples

NCT ID: NCT06012019

This clinical trial is investigating a common gum disease called periodontitis, which affects many adults and can lead to serious health issues. The researchers want to understand how certain immun...